{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T23:21:23Z","timestamp":1773184883231,"version":"3.50.1"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Urologia"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Dilation of the renal pelvis is a problem Urologists have often to deal with. One of the key aspects is to clear if the dilation is the consequence of an obstruction to the outflow or a simple anatomic variant. Aim of this study was to compare two diuretic renographic procedures, F-15 vs the new procedure F+10SP (Seated Position) in a group of hydronephrotic patients, in order to increase the accuracy in the differential diagnosis between non-obstructive and obstructive dilation. <\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p> 34 Patients (14 male, 20 female, 18\u201371 yrs range), 27 pts having an unilateral hydronephrosis and 7 pts a bilateral hydronephrosis diagnosed by ultrasound, were enclosed in the study. They were subjected to two 99mTc-MAG3 diuretic renography with furosemide consecutively, with different modalities: 1) 40 mg of furosemide were administered IV to patient in supine position 15 minutes before tracer injection (Test F-15, by English); 2) the new procedure: 20 mg of furosemide were administered IV to patient in Seated Position (SP), 10 minutes after tracer injection during dynamic acquisition (Test F+10 SP). The average interval between the two tests was 7 days. Two different physicians analyzed all the tests. The results were classified as: non-obstruction (only F+10SP can distinguish between normal and dilated without obstruction), obstruction, equivocal and not applicable. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Among the 68 renal units (RU) included in the analysis, the F+10SP test showed normal findings in 21 RU (30,8%), dilation without obstruction in 21 RU (30,8%), obstruction in 25 RU (36.8%) and equivocal result in 1 RU. The F-15 renography showed non-obstructive results in 35 RU (51.5%), obstruction in 20 RU (29.4%) and equivocal findings in 11 RU (16.1%); the test was not applicable in 2 RU (2.9%) due to insufficient renal function. Side effects reported for the F-15 renogram were hypotension in 1 patient, renal colic in 3 patients, bladder filling in 13 patients, disruption because of voiding in 4 patients. No complications were observed during or after the F+10SP renography. The 20 RU diagnosed with obstruction at the F-15 test were considered obstructed also at the F+10SP test. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> The \u201cequivocal\u201d test rate lowered from 16% for the F-15 test to less than 1.5% for the new F+10 SP test. The F+10SP procedure is easy, well tolerated, time saving and seems to be a more reliable tool in assessment of obstructive uropathy in adults. <\/jats:p><\/jats:sec>","DOI":"10.5301\/ru.2011.8633","type":"journal-article","created":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T02:13:08Z","timestamp":1316139188000},"page":"221-226","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["<sup>99M<\/sup>Tc-MAG3 Diuretic Renography in Assessment of Obstructive Uropathy. The new test F+10SP: a Step Ahead in the Differential Diagnosis"],"prefix":"10.1177","volume":"78","author":[{"given":"Matteo","family":"Vittori","sequence":"first","affiliation":[{"name":"Department of Urology, Catholic University of Sacred Heart, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"D'addessi","sequence":"additional","affiliation":[{"name":"Department of Urology, Catholic University of Sacred Heart, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Urology, Catholic University of Sacred Heart, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girolamo","family":"Tartaglione","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Unit, Cristo Re Hospital, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierfrancesco","family":"Bassi","sequence":"additional","affiliation":[{"name":"Department of Urology, Catholic University of Sacred Heart, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,9,15]]},"reference":[{"key":"bibr1-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)43157-0"},{"issue":"11","key":"bibr2-RU.2011.8633","first-page":"1872","volume":"37","author":"O'Reilly P.","year":"1996","journal-title":"J Nucl Med"},{"key":"bibr3-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1978.tb03030.x"},{"key":"bibr4-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-199419120-00002"},{"key":"bibr5-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.2967\/jnmt.108.056622"},{"key":"bibr6-RU.2011.8633","first-page":"1587","volume-title":"Nuclear medicine in clinical diagnosis and treatment.","author":"Brown S.C.W.","year":"2004","edition":"3"},{"key":"bibr7-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1987.tb04570.x"},{"issue":"11","key":"bibr8-RU.2011.8633","first-page":"1805","volume":"40","author":"Wong D.C.","year":"1999","journal-title":"J Nucl Med"},{"key":"bibr9-RU.2011.8633","first-page":"1317","volume":"46","author":"Liu Y.","year":"2005","journal-title":"J Nucl Med"},{"key":"bibr10-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1992.tb15479.x"},{"key":"bibr11-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1007\/s002470000270"},{"key":"bibr12-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-009-1538-5"},{"key":"bibr13-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1097\/01.mnm.0000080242.50447.68"},{"issue":"3","key":"bibr14-RU.2011.8633","first-page":"21","volume":"28","author":"Gordon I.","year":"2001","journal-title":"Eur J Nucl Med"},{"issue":"6","key":"bibr15-RU.2011.8633","first-page":"1030","volume":"41","author":"Wong D.C.","year":"2000","journal-title":"J Nucl Med"},{"key":"bibr16-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1053\/j.semnuclmed.2010.07.008"},{"key":"bibr17-RU.2011.8633","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-007-0641-9"}],"container-title":["Urologia Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/RU.2011.8633","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/RU.2011.8633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,2]],"date-time":"2025-03-02T12:11:02Z","timestamp":1740917462000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/RU.2011.8633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.5301\/RU.2011.8633"],"URL":"https:\/\/doi.org\/10.5301\/ru.2011.8633","relation":{},"ISSN":["0391-5603","1724-6075"],"issn-type":[{"value":"0391-5603","type":"print"},{"value":"1724-6075","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}