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Recently, a new class of drugs, vasopressin V2-receptor antagonists (vaptans), emerged as a promising treatment for SIADH, but efficacy and safety data in cancer patients are lacking. We present a case of SIADH, heralding small cell lung cancer and persisting after apparent complete remission of primary tumor following chemotherapy\/radiotherapy, in a patient who underwent long-term treatment with tolvaptan without any serious adverse effects. <\/jats:p>","DOI":"10.5301\/tj.5000249","type":"journal-article","created":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T10:50:43Z","timestamp":1424688643000},"page":"e51-e53","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy and Safety of Long-term Tolvaptan Treatment in a Patient with SCLC and SIADH"],"prefix":"10.1177","volume":"101","author":[{"given":"Paola","family":"Bordi","sequence":"first","affiliation":[{"name":"Medical Oncology Unit, University Hospital of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Tiseo","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University Hospital of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiano","family":"Buti","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University Hospital of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Regolisti","sequence":"additional","affiliation":[{"name":"Pathophysiology of Acute and Chronic Renal Failure Unit, Department of Clinical and Experimental Medicine, University of Parma, University Hospital of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ardizzoni","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University Hospital of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4,28]]},"reference":[{"key":"bibr1-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2011-0400"},{"key":"bibr2-tj.5000249","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0099"},{"key":"bibr3-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1986.4.8.1191"},{"key":"bibr4-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1995.tb00907.x"},{"key":"bibr5-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1990.133"},{"key":"bibr6-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2009.05.015"},{"key":"bibr7-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065181"},{"key":"bibr8-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009080857"},{"key":"bibr9-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008369932384"},{"key":"bibr10-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-13-55"},{"key":"bibr11-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28468"},{"key":"bibr12-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr431"},{"key":"bibr13-tj.5000249","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.43.5545"},{"key":"bibr14-tj.5000249","author":"Makin A.","year":"2013","journal-title":"Small cell lung cancer and hyponatremia: interim results from a prospective, observational, global registry."},{"key":"bibr15-tj.5000249","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2009.03.1991"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/tj.5000249","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T19:53:17Z","timestamp":1741031597000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/tj.5000249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.5301\/tj.5000249"],"URL":"https:\/\/doi.org\/10.5301\/tj.5000249","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3]]}}}