{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T05:50:43Z","timestamp":1740981043769,"version":"3.38.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:p> Patients with advanced and incurable colorectal cancer have a very poor prognosis. Curative-intent resection was performed in 70%\u201390% of cases in reported series of colorectal cancer, sometimes after neoadjuvant chemotherapy and radiotherapy. The remaining 10%-30% of patients are treated with palliative intent, where treatment is aimed at relieving disease-related symptoms and improving quality of life. The provision of palliative care for these patients is complicated and outcomes are often disappointing. Although there are many available options including a variety of surgical and nonsurgical interventions, the best management remains controversial. Transarterial chemoembolization with irinotecan-loaded drug-eluting beads (DEBIRI) is an effective, minimally invasive procedure performed by interventional radiologists that allows intra-arterial drug delivery to stop vascular feeding and exert local cytotoxic effects. We here report on a patient treated with DEBIRI followed by systemic chemotherapy with the FOLFOX regimen for locally advanced, inoperable colorectal cancer. <\/jats:p>","DOI":"10.5301\/tj.5000270","type":"journal-article","created":{"date-parts":[[2015,4,24]],"date-time":"2015-04-24T11:49:41Z","timestamp":1429876181000},"page":"e82-e84","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Inferior Mesenteric Artery Chemoembolization and Chemotherapy for Advanced Rectal Cancer: Report of a Clinical Case"],"prefix":"10.1177","volume":"101","author":[{"given":"Roberto","family":"Bini","sequence":"first","affiliation":[{"name":"General Surgery Department, SG Bosco Hospital ASL To2, Turin - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Comelli","sequence":"additional","affiliation":[{"name":"Interventional Radiology\/Neuroradiology, SG Bosco Hospital ASL To2, Turin - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Addeo","sequence":"additional","affiliation":[{"name":"Lincoln County Hospital, Lincoln - 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