{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T05:20:55Z","timestamp":1738041655494,"version":"3.33.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Peripheral T-cell lymphomas (PTCL) represent a heterogeneous group of hematologic malignancies frequently presenting at advanced stage of diagnosis. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We report a case of PTCL with an uncommon and aggressive onset with disseminated intravascular coagulation (DIC). <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Laboratory findings revealed an aberrant expression of \u03b2 subunit of human chorionic gonadotropin (\u03b2-HCG). Other than for determination of pregnancy, \u03b2-HCG is regularly found as a tumor marker in germ cell tumors with trophoblastic differentiation and its aberrant expression has been reported in the literature in other neoplastic conditions only in the context of case reports. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> In hematologic malignancies, \u03b2-HCG expression has been described only in sporadic cases. Awareness of this feature could avoid diagnostic delay in such an aggressive disease. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000373","type":"journal-article","created":{"date-parts":[[2015,6,25]],"date-time":"2015-06-25T10:32:07Z","timestamp":1435228327000},"page":"e160-e162","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Hepatosplenic T-cell Lymphoma with Aberrant Expression of Serum \u03b2-HCG: A Case Report"],"prefix":"10.1177","volume":"101","author":[{"given":"Andrea","family":"Bellodi","sequence":"first","affiliation":[{"name":"Clinic of Internal Medicine 3, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Rivoli","sequence":"additional","affiliation":[{"name":"Clinic of Hematology, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Arboscello","sequence":"additional","affiliation":[{"name":"Clinic of Internal Medicine 3, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Fornarini","sequence":"additional","affiliation":[{"name":"Medical Oncology, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulio Fraternali","family":"Orcioni","sequence":"additional","affiliation":[{"name":"Clinic of Hematology, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Avenoso","sequence":"additional","affiliation":[{"name":"Clinic of Hematology, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Miglino","sequence":"additional","affiliation":[{"name":"Clinic of Hematology, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Ghio","sequence":"additional","affiliation":[{"name":"Clinic of Internal Medicine 3, Department of Internal Medicine, Istituto di Ricerca a Carattere Clinico e Scientifico (IRCCS), Azienda Ospedaliera Universitaria (AOU) San Martino, Istituto Nazionale Tumori (IST), Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,11,14]]},"reference":[{"key":"bibr1-tj.5000373","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-013-0232-x"},{"key":"bibr2-tj.5000373","unstructured":"SwerdlowSH CampoE HarrisNL  WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. Lyon, France: IARC Press 2008."},{"key":"bibr3-tj.5000373","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2011.10.001"},{"key":"bibr4-tj.5000373","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdn751"},{"key":"bibr5-tj.5000373","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199906000-00012"},{"issue":"9","key":"bibr6-tj.5000373","first-page":"3611","volume":"33","author":"Burczynska BI","year":"2013","journal-title":"Anticancer Res"},{"key":"bibr7-tj.5000373","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054592"},{"key":"bibr8-tj.5000373","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2013.805810"},{"issue":"5","key":"bibr9-tj.5000373","first-page":"402","volume":"137","author":"Senba M","year":"1991","journal-title":"Zentralbl Pathology"},{"key":"bibr10-tj.5000373","doi-asserted-by":"publisher","DOI":"10.2350\/07-03-0251.1"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000373","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/tj.5000373","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000373","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T15:43:59Z","timestamp":1728488639000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/tj.5000373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.5301\/tj.5000373"],"URL":"https:\/\/doi.org\/10.5301\/tj.5000373","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"type":"print","value":"0300-8916"},{"type":"electronic","value":"2038-2529"}],"subject":[],"published":{"date-parts":[[2015,11]]}}}