{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T05:46:15Z","timestamp":1738129575981,"version":"3.33.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"2_suppl","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> The role of surgery in recurrent ovarian cancer (ROC) is debated. Multiple prospective and retrospective series reported improved survival with optimal secondary surgical cytoreduction, but definitive results from randomized trials are needed. Up to the fourth cytoreductive surgery for recurrent disease in an attempt to improve patients\u2019 prognosis has been reported. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p> We report the first case of multiple ROC in an Italian woman, 50 years old at diagnosis, who underwent 9 cytoreductive surgeries during her 17 years of disease with no serious postoperative complications. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> Multiple surgeries should not be considered as the standard treatment for ROC. In carefully selected patients, optimal cytoreductive surgery performed by highly specialized gynecologic oncologists might represent a useful tool in adjunction to chemotherapy for the management of ROC. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000427","type":"journal-article","created":{"date-parts":[[2015,10,2]],"date-time":"2015-10-02T11:31:50Z","timestamp":1443785510000},"page":"S78-S81","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Beyond the Beyond: First Case of 9 Cytoreductive Surgeries in a Long-Surviving Ovarian Cancer Patient: Case Report"],"prefix":"10.1177","volume":"102","author":[{"given":"Laura","family":"Salerno","sequence":"first","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Marchetti","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Bevilacqua","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Musella","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Riganelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilary","family":"Ruscito","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgia","family":"Perniola","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovico","family":"Muzii","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierluigi","family":"Benedetti Panici","sequence":"additional","affiliation":[{"name":"Department of Obstetrico-Gynecological and Urologic Sciences, \u201cSapienza\u201d University of Rome, Rome - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,11,11]]},"reference":[{"key":"bibr1-tj.5000427","first-page":"CD008765","volume":"2","author":"Al Rawahi T","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr2-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0b013e31820aaafd"},{"key":"bibr3-tj.5000427","first-page":"613980","volume":"2012","author":"Lorusso D","year":"2012","journal-title":"Int J Surg Oncol"},{"key":"bibr4-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.09.017"},{"key":"bibr5-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2673-z"},{"key":"bibr6-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2013.02.006"},{"key":"bibr7-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-8-367"},{"issue":"10","key":"bibr8-tj.5000427","first-page":"2605","volume":"23","author":"Hanker LC","year":"2012","journal-title":"The impact of second to sixth line therapy on survival of relapsed ovarian cancer after primary taxane\/platinum-based therapy. Ann Oncol"},{"key":"bibr9-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908806"},{"key":"bibr10-tj.5000427","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2010.06.006"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000427","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/tj.5000427","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T16:27:15Z","timestamp":1738081635000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/tj.5000427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":10,"journal-issue":{"issue":"2_suppl","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.5301\/tj.5000427"],"URL":"https:\/\/doi.org\/10.5301\/tj.5000427","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"type":"print","value":"0300-8916"},{"type":"electronic","value":"2038-2529"}],"subject":[],"published":{"date-parts":[[2016,11]]}}}