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The diagnosis of malignancy is challenging because there are no available histopathologic criteria. In these cases, the prognosis is usually poor. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We report a case of a woman with malignant paranasal sinus paragangliomas. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> The patient was treated with several surgical approaches, radiotherapy, and medical therapy for different recurrences. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> Despite the malignant behavior of the disease, this patient is still alive many years after first diagnosis. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000443","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T17:51:06Z","timestamp":1445363466000},"page":"S9-S11","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Long-Term Survival in a Patient with Head and Neck Paraganglioma Treated with Tailored Modalities for 20 Years: A Case Report"],"prefix":"10.1177","volume":"102","author":[{"given":"Liliana","family":"Belgioia","sequence":"first","affiliation":[{"name":"Division of Radiation Oncology, AOU IRCCS San Martino-IST National Cancer Research Institute and University, Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pupillo","sequence":"additional","affiliation":[{"name":"Division of Medical Physics, AOU IRCCS San Martino-IST National Cancer Research Institute and University, Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almalina","family":"Bacigalupo","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, AOU IRCCS San Martino-IST National Cancer Research Institute and University, Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renzo","family":"Corv\u00f2","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, AOU IRCCS San Martino-IST National Cancer Research Institute and University, Genoa - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,11,11]]},"reference":[{"key":"bibr1-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23985"},{"key":"bibr2-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2320"},{"key":"bibr3-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-13-0223"},{"key":"bibr4-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-14-0396"},{"key":"bibr5-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1177\/019459988910100117"},{"key":"bibr6-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2003.09.004"},{"key":"bibr7-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1836"},{"key":"bibr8-tj.5000443","first-page":"4006","volume":"98","author":"Hescot S","year":"2013","journal-title":"One-year progression-free survival of therapy-naive patients with malignant pheochromocytoma and paraganglioma."},{"key":"bibr9-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-1544"},{"key":"bibr10-tj.5000443","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.2002.1413"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/tj.5000443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T23:05:05Z","timestamp":1728083105000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/tj.5000443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":10,"journal-issue":{"issue":"2_suppl","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.5301\/tj.5000443"],"URL":"https:\/\/doi.org\/10.5301\/tj.5000443","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"type":"print","value":"0300-8916"},{"type":"electronic","value":"2038-2529"}],"subject":[],"published":{"date-parts":[[2016,11]]}}}