{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T05:43:06Z","timestamp":1738129386914,"version":"3.33.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2015,10,31]],"date-time":"2015-10-31T00:00:00Z","timestamp":1446249600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> Daily image-guided radiation therapy significantly reduces setup errors, but it does not minimize intrafractional target mobility; respiratory-induced target motion is one of the reasons for this. Therefore, the main aim of this study was to evaluate the impact of respiratory-induced prostate motion on the clinical target volume (CTV) margins. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> The analysis comprised 50 videos stored in digital format and recorded in a group of 50 patients during image-guided radiation therapy for prostate cancer. Fluoroscopy time was 10 seconds. Respiratory motion of the prostate in the anterior-posterior and lateral direction was assessed on the basis of a fiducial marker (GoldAnchor) implanted into the prostate before the treatment planning procedure. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> The average values and standard deviations of respiratory-induced prostate motion in the superior-inferior and left-right (lateral) directions were 2.6 \u00b1 2.1 mm and 0.7 \u00b1 0.7 mm, respectively. The CTV margins calculated according to the van Herk formula based on respiratory prostate motion were 8 mm in the superior-inferior direction and 2 mm in the lateral direction. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> Respiratory-induced prostate mobility during radiotherapy is significant especially in the superior-inferior direction, and can thus induce a geographical error. This confirms the need for determining CTV margins for this type of respiratory-induced mobility. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000446","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T11:29:38Z","timestamp":1446809378000},"page":"330-334","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Intrafractional Respiratory-Induced Prostate Mobility on PTV Size"],"prefix":"10.1177","volume":"102","author":[{"given":"Dawid","family":"Bodusz","sequence":"first","affiliation":[{"name":"Radiotherapy Department, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice - Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leszek","family":"Miszczyk","sequence":"additional","affiliation":[{"name":"Radiotherapy Department, Maria Sk\u0142odowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice - Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,10,31]]},"reference":[{"key":"bibr1-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2008.08.002"},{"key":"bibr2-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(91)90244-X"},{"key":"bibr3-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)03008-0"},{"key":"bibr4-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00225-1"},{"key":"bibr5-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00116-6"},{"key":"bibr6-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2006.05.012"},{"key":"bibr7-tj.5000446","first-page":"7","volume":"65","author":"Miszczyk L","year":"2008","journal-title":"Przegl Lek"},{"key":"bibr8-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2010.01.004"},{"key":"bibr9-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.06.1195"},{"key":"bibr10-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1053\/j.semradonc.2003.10.003"},{"key":"bibr11-tj.5000446","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(02)00140-8"},{"volume-title":"Prescribing, recording and reporting photon beam therapy (Supplement to ICRU Report 50). 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