{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T07:05:37Z","timestamp":1776755137384,"version":"3.51.2"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T00:00:00Z","timestamp":1493337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> To evaluate the diagnostic yield and complication rate of 2 different biopsy techniques (fine-needle aspiration, FNA, and core-needle biopsy, CNB) in the diagnosis of pulmonary lesions in 2 distinct periods, 2010-2012 and 2013-2015. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We retrospectively analyzed the results of 691 CT-guided lung biopsies in 665 patients who were divided into 2 groups: cohort 1 (January 2010 to December 2012) was composed of 271 consecutive patients with 284 procedures either by FNA or CNB; cohort 2 (January 2013 to December 2015) was composed of 394 patients with 407 CNBs. Univariate and multivariate logistic regression modeling was used for selected outcomes including diagnostic yield, bleeding and pneumothorax. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Cohort 1 comprised 165 men and 106 women (mean age 68.5 years) with 180 FNAs and 104 CNBs; cohort 2 comprised 229 men and 165 women (mean age 66.4 years) with 407 CNBs. The diagnostic yield increased in cohort 2 with respect to cohort 1. There was a slight increase in CT procedure complications (pneumothorax and bleeding) from cohort 1 to cohort 2. The overall risk of complications was greater for lesions &lt;20 mm and for lesions at &gt;20 mm distance from the pleura. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> CT-guided CNB had a higher diagnostic yield than discretional use of either FNA or CNB; there was a slight but acceptable increase in complication rates. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000633","type":"journal-article","created":{"date-parts":[[2017,5,7]],"date-time":"2017-05-07T10:48:46Z","timestamp":1494154126000},"page":"360-366","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["FNA and CNB in the Diagnosis of Pulmonary Lesions: A Single-center Experience on 665 Patients, Comparison between Two Periods"],"prefix":"10.1177","volume":"103","author":[{"given":"Alfonso Vittorio","family":"Marchian\u00f2","sequence":"first","affiliation":[{"name":"Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Cosentino","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"},{"name":"School of Specialization of Diagnostic and Interventional Radiology, University of Milan, San Donato Milanese (Milan) - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Di Tolla","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca Gabriella","family":"Greco","sequence":"additional","affiliation":[{"name":"Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Section of Radiology, University of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Sverzellati","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Section of Radiology, University of Parma, Parma - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Fabbri","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Tamborini","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Lo","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Mariani","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Trial Organization, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Lalli","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Trial Organization, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugo","family":"Pastorino","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,4,28]]},"reference":[{"key":"bibr1-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2000.0964"},{"key":"bibr2-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1177\/0284185113481595"},{"key":"bibr3-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(03)00221-6"},{"key":"bibr4-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20258"},{"key":"bibr5-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.58.11.920"},{"key":"bibr6-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099314"},{"key":"bibr7-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2010.06.007"},{"key":"bibr8-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2004.09.006"},{"issue":"5","key":"bibr9-tj.5000633","doi-asserted-by":"crossref","first-page":"622","DOI":"10.5858\/2010-0625-RAIR.1","volume":"135","author":"Dacic S.","year":"2011","journal-title":"Arch Pathol Lab Med."},{"key":"bibr10-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1080\/02841850802294410"},{"key":"bibr11-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2013.07.010"},{"key":"bibr12-tj.5000633","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2858"},{"key":"bibr13-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2006.02.001"},{"key":"bibr14-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.5.1521"},{"key":"bibr15-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.212.1.r99jl33165"},{"key":"bibr16-tj.5000633","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-0443(07)61556-5"},{"key":"bibr17-tj.5000633","doi-asserted-by":"publisher","DOI":"10.3109\/02841851003691979"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000633","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.5301\/tj.5000633","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.5301\/tj.5000633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T19:19:52Z","timestamp":1738005592000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.5301\/tj.5000633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,28]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.5301\/tj.5000633"],"URL":"https:\/\/doi.org\/10.5301\/tj.5000633","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,28]]}}}