{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T18:14:52Z","timestamp":1759601692352,"version":"3.38.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T00:00:00Z","timestamp":1525737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Purpose:<\/jats:title><jats:p> The aim of this work was to investigate the predictive factors for bladder cancer recurrence survival (BCRS) in patients with upper-tract urothelial carcinoma (UTUC). <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> We selected patients with UTUC who underwent segmental ureterectomy (Su) or nephroureterectomy (Nu) from 2004 to 2013 from the Surveillance, Epidemiology, and End Results (SEER) database. Patients with a history of intravesical therapy for bladder cancer and bladder cancer prior to the diagnosis of UTUC were excluded. We used Kaplan-Meier analysis, log-rank tests, and Cox proportional hazards model to compare overall survival, cancer-specific survival, and BCRS. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> In a cohort of 1,454 patients, 169 (11.6%) had low-grade tumors and 1,285 (88.4%) had high-grade tumors; 239 (16.4%) underwent Su and 1,215 (83.6%) underwent Nu. We found that T4 grade (hazard ratio [HR] = 6.216; 95% confidence interval [CI], 3.197-12.087) and ureteral tumors (HR = 1.764; 95% CI, 1.173-2.652) were predictors of shorter BCRS, whereas Nu (HR = 0.608; 95% CI, 0.388-0.953) predicted longer BCRS. Five-year BCRS rates were low-grade tumors: 94.1%, high-grade tumors: 85.4% (p = 0.038); plus Su: 82.9%, and Nu: 87.6% (p = 0.016). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Use of Su should be more selective for high-grade tumors, as it correlates with shorter BCRS. Tumors located in the ureter are associated with shorter BCRS than those located in the renal pelvis. <\/jats:p><\/jats:sec>","DOI":"10.5301\/tj.5000705","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T16:25:05Z","timestamp":1535127905000},"page":"451-458","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Risk factors for bladder cancer recurrence survival in patients with upper-tract urothelial carcinoma"],"prefix":"10.1177","volume":"104","author":[{"given":"Yu-Peng","family":"Wu","sequence":"first","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-Zhi","family":"Lin","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Yi","family":"Lin","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting-Ting","family":"Lin","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Wei","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Shui","family":"Zheng","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Yi","family":"Xue","sequence":"additional","affiliation":[{"name":"Departments of Urology, First Affiliated Hospital of Fujian Medical University, Fuzhou - 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