{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T19:40:25Z","timestamp":1740685225110,"version":"3.38.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T00:00:00Z","timestamp":1479686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Ophthalmology"],"published-print":{"date-parts":[[2017,6,26]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p> To assess the impact of metabolic syndrome (MetS) on the peripapillary choroidal thickness (PPCT) and to characterize the PPCT in a Portuguese population. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> This prospective study included 104 eyes. Detailed medical and ophthalmic examinations were performed; the PPCT was measured by spectral-domain optical coherence tomography (SD-OCT) using enhanced depth imaging (EDI) modality. The PPCT changes with MetS, as well as with other clinical and demographic factors, were investigated. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> The mean PPCT was 142.4 \u00b1 54.0 \u00b5m (58-303 \u00b5m); it was thickest superiorly, followed by the temporal, nasal, and inferior sectors. The PPCT was significantly associated with axial length (p&lt;0.001), age (p = 0.001), intraocular pressure (IOP) (p = 0.041), weight (p = 0.015), and arterial hypertension (p = 0.044). The presence of MetS was associated with thinner PPCT in all sectors, being statistically significant in the temporal (p = 0.032) and inferotemporal (p = 0.034) sectors. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> The choroidal thickness was significantly less in temporal and inferotemporal sectors in patients with MetS than in controls. This may suggest vascular insufficiency around the optic nerve head. <\/jats:p><\/jats:sec>","DOI":"10.5301\/ejo.5000911","type":"journal-article","created":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T17:26:35Z","timestamp":1480094795000},"page":"428-432","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Peripapillary Choroidal Thickness by Enhanced Depth Imaging Optical Coherence Tomography: The Impact of Metabolic Syndrome"],"prefix":"10.1177","volume":"27","author":[{"given":"M\u00f3nica","family":"Loureiro","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de V. N. Gaia\/Espinho, Vila Nova de Gaia - Portugal"},{"name":"Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto - Portugal"}]},{"given":"Ana Cristina","family":"Braga","sequence":"additional","affiliation":[{"name":"ALGORITMI Centre, University of Minho, Braga - Portugal"}]},{"given":"D\u00e1lia","family":"Meira","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de V. N. Gaia\/Espinho, Vila Nova de Gaia - Portugal"}]},{"given":"Paula","family":"Sep\u00falveda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de V. N. Gaia\/Espinho, Vila Nova de Gaia - Portugal"}]},{"given":"Lu\u00eds","family":"Agrelos","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Centro Hospitalar de V. N. Gaia\/Espinho, Vila Nova de Gaia - Portugal"}]},{"given":"Paulo","family":"Torres","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto - Portugal"},{"name":"Department of Ophthalmology, Centro Hospitalar do Porto, Porto - Portugal"}]}],"member":"179","published-online":{"date-parts":[[2016,11,21]]},"reference":[{"key":"bibr1-ejo.5000911","unstructured":"KaufmanPL AlmA Anatomy of the ocular circulation. Adler's physiology of the eye. 10th ed. 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