{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:06:23Z","timestamp":1785197183287,"version":"3.55.0"},"reference-count":71,"publisher":"Baishideng Publishing Group Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJCO"],"published-print":{"date-parts":[[2022,5,24]]},"DOI":"10.5306\/wjco.v13.i5.323","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T05:43:58Z","timestamp":1653371038000},"page":"323-338","source":"Crossref","is-referenced-by-count":8,"title":["Tumor specifically internalizing peptide \u2018HN-1\u2019: Targeting the putative receptor retinoblastoma-regulated discoidin domain receptor 1 involved in metastasis"],"prefix":"10.5306","volume":"13","author":[{"given":"Frank-Un","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Linse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301213280306"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0696-682"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1126\/science.3823889"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1101\/gad.282145.116"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-018-0008-5"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-00224-3"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.11.031"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1186\/bcr432"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-18-0554"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-018-0185-6"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2009.10.032"},{"key":"B12","unstructured":"Hong FD, Clayman GL. Isolation of a peptide for targeted drug delivery into human head and neck solid tumors. Cancer Res 2000; 60: 6551-6556"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.243824"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1021\/ct500592m"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks419"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v11.i11.854"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.14.5502"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.19.7762"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/329642a0"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1007\/BF01182484"},{"key":"B21","doi-asserted-by":"crossref","unstructured":"Hensey CE, Hong F, Durfee T, Qian YW, Lee EY, Lee WH. Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization. J Biol Chem 1994; 269: 1380-1387","DOI":"10.1016\/S0021-9258(17)42269-1"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1101\/sqb.1991.056.01.026"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1101\/sqb.1994.059.01.013"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/20.7.1161"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0b013e32801429ed"},{"key":"B26","unstructured":"Un F, Qi C, Prosser M, Wang N, Zhou B, Bronner C, Yen Y. Modulating ICBP90 to suppress human ribonucleotide reductase M2 induction restores sensitivity to hydroxyurea cytotoxicity. Anticancer Res 2006; 26: 2761-2767"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1126\/science.3201247"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1126\/science.2300823"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1126\/science.2274789"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/nm0996-985"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.6.2221"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5340.1073"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1021\/cr400525m"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-019-2058-1"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201102147"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00125"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.21.8.2906-2917.2001"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2133"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-1686"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.06.009"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-17-0710"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201707918"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1080\/19336918.2018.1520556"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12040841"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201404079"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2010.07.004"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200708137"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2019.04.003"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2017.4165"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdg129"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0626fje"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-53176-4"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200106070"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(02)00906-6"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.5402\/2011\/140316"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.10.067"},{"key":"B57","unstructured":"Zheng X.   Specificity and feasibility of HN-5 peptide for diagnosis and targeted therapy of head and neck squamous cell carcinomas. Thesis, The University of Texas Health Science Center at San Antonio, 2007. Available from: https:\/\/www.proquest.com\/products-services\/dissertations\/Milestone-Editions-for-Authors.html"},{"key":"B58","unstructured":"Un F, Zhou B, Yen Y. The utility of tumor-specifically internalizing peptides for targeted siRNA delivery into human solid tumors. Anticancer Res 2012; 32: 4685-4690"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3465"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-010-0242-8"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.wjorl.2016.05.006"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2017.04.027"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-81218-3"},{"key":"B64","unstructured":"Henri JT, McChesney JD, Lamb R, Venkataraman SK.   Molecular construct suitable for targeted conjugates. United States Patent Application 20090246211. Available from: https:\/\/www.freepatentsonline.com\/20090246211.pdf"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24173070"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-00573"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-2258"},{"key":"B68","unstructured":"Un F.   Finding the genetic solution for cancer in the mechanism of Taxol cytotoxicity. In: Meszaros A, Balogh G. Multiple Drug Resistance. New York: Nova Science Publishers, 2010: 219-223"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-2218"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1038\/nature08956"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2021.1876182"}],"container-title":["World Journal of Clinical Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2218-4333\/full\/v13\/i5\/323.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T05:44:09Z","timestamp":1653371049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2218-4333\/full\/v13\/i5\/323.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,24]]},"references-count":71,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.5306\/wjco.v13.i5.323","relation":{},"ISSN":["2218-4333"],"issn-type":[{"value":"2218-4333","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5,24]]}}}