{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T03:50:38Z","timestamp":1777607438711,"version":"3.51.4"},"reference-count":28,"publisher":"Baishideng Publishing Group Inc.","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Clin Oncol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Cervical myeloid sarcoma (MS) is a rare hematological malignancy characterized by the formation of extramedullary soft tissue masses in the cervical region. Due to its uncommon presentation in the female reproductive system, cervical MS poses significant diagnostic and therapeutic challenges. Consequently, there is a pressing need for more research and clinical experience to better understand, diagnose, and manage this condition effectively.<\/jats:p>\n          <jats:p>CASE SUMMARY<\/jats:p>\n          <jats:p>This report details four cases, the diagnostic process, treatment strategy, and outcomes, discussing cervical MS as an initial clinical manifestation. The disease exhibits varied clinical presentations, such as irregular vaginal bleeding and palpation of cervical masses. The treatment approaches discussed include neoadjuvant chemotherapy, surgery, and postoperative chemotherapy, though managing the disease remains challenging. The report also features a comprehensive literature review that underscores the importance of immunohistochemistry for accurate diagnosis, identifying key markers, including myeloperoxidase, cluster of differentiation (CD) 68, and CD43, stressing the need for further research to improve treatment strategies and prognosis.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Immunohistochemical diagnosis and tailored therapeutic strategies are essential. Further research is crucial in improving outcomes and developing effective treatment protocols.<\/jats:p>","DOI":"10.5306\/wjco.v15.i10.1324","type":"journal-article","created":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T01:40:42Z","timestamp":1727574042000},"page":"1324-1332","source":"Crossref","is-referenced-by-count":2,"title":["Cervical myeloid sarcoma as an initial clinical manifestation: Four case reports"],"prefix":"10.5306","volume":"15","author":[{"given":"Jin-Ke","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Xue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-Jun","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan-Dan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1159\/000497210"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2017.02.027"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2020.100773"},{"key":"B4","unstructured":"Jiang QM, Lu P, Zhou WW, Ye XZ, Li J. [Clinicopathologic study of 6 patients with myeloid sarcoma]. Linchuang Zhongliuxue Zazhi 2015; 20: 351-356"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1006-1959.2014.39.038"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1673-5412.2.13.06.004"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.14188\/j.1671-8852.2014.04.022"},{"key":"B8","unstructured":"Peng JF, Wang HR, Wang JT, Jiang HL. [MRI diagnosis and literature review of primary granulocytic sarcoma of cervix]. Guoji Yixue Fangshexue Zazhi 2019; 42: 470-473"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.11877\/j.issn.1672-1535.2016.14.05.12"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1672-7185.2013.08.028"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.7534\/j.issn.1009-2137.2017.03.052"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2095-6959.2017.10.017"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1007-8096.2017.04.008"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.13315\/j.cnki.cjcep.2013.01.013"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2454-8"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-207395"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.4274\/balkanmedj.2017.0941"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/501342"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2019.10652"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-021-01328-y"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000031559"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1177\/2040620711410774"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-6357-y"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000727"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1080\/10245332.2017.1333275"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2023.04.009"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2021.01.004"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-023-05288-1"}],"container-title":["World Journal of Clinical Oncology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/2218-4333\/full\/v15\/i10\/1324.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/2218-4333\/full\/v15\/i10\/1324.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,29]],"date-time":"2024-09-29T01:41:14Z","timestamp":1727574074000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/2218-4333\/full\/v15\/i10\/1324.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,24]]},"references-count":28,"journal-issue":{"issue":"10"},"URL":"https:\/\/doi.org\/10.5306\/wjco.v15.i10.1324","relation":{},"ISSN":["2218-4333"],"issn-type":[{"value":"2218-4333","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10,24]]}}}