{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T07:40:18Z","timestamp":1736754018129,"version":"3.32.0"},"reference-count":39,"publisher":"Baishideng Publishing Group Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Orthop"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Fracture nonunion represents a challenging complication during fracture repair, often necessitating surgical intervention. Teriparatide, a recombinant human parathyroid hormone, has demonstrated promise in enhancing fracture healing, although its efficacy in treating established nonunion remains under investigation.<\/jats:p>\n          <jats:p>CASE SUMMARY<\/jats:p>\n          <jats:p>We report a case of a 27-year-old male who presented with a right humerus fracture following a traffic accident. Despite undergoing open reduction and internal fixation, the fracture resulted in a delayed union and subsequent nonunion. After 4 years of conservative management, teriparatide treatment was initiated due to persistent nonunion. Teriparatide injections were administered daily for 6 months, resulting in complete fracture healing and resolution of pain.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Our case demonstrates the successful use of teriparatide in treating a prolonged nonunion of a humerus fracture. Teriparatide may provide a valuable therapeutic option for established bone nonunion, even in cases that have not responded to conservative treatments.<\/jats:p>","DOI":"10.5312\/wjo.v16.i1.101656","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T06:31:56Z","timestamp":1736749916000},"source":"Crossref","is-referenced-by-count":0,"title":["Teriparatide as a non-surgical salvage therapy for prolonged humerus fracture nonunion: A case report and literature review"],"prefix":"10.5312","volume":"16","author":[{"given":"Shao-Han","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Jun","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2025,1,18]]},"reference":[{"key":"B1","unstructured":"Qu Z, Fang G, Cui Z, Liu Y. 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