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Clinical studies have demonstrated the efficacy of PRP in managing conditions such as knee osteoarthritis, rotator cuff tendinopathy, and lateral epicondylitis, often showing superior long-term benefits compared with conventional treatments. Emerging therapies that combine PRP with mesenchymal stem cells and peptide-based treatments have shown synergistic effects, further enhancing tissue regeneration and functional recovery. Despite these promising developments, variability in PRP preparation methods and application protocols underscores the need for standardized guidelines and large-scale clinical trials to fully establish the role of PRP in orthopedic practice.<\/jats:p>","DOI":"10.5312\/wjo.v16.i12.110377","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T01:10:30Z","timestamp":1765933830000},"source":"Crossref","is-referenced-by-count":3,"title":["Platelet rich plasma applications in orthopedics: A review of recent advances"],"prefix":"10.5312","volume":"16","author":[{"given":"Arnav Pankaj","family":"Rathod","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Rathod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendra","family":"Baitule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh","family":"Pundkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hrishikesh","family":"Saodekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2025,12,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14062061"},{"key":"B2","unstructured":"Stokes DJ, Frank RM, Platelet-Rich Plasma for Osteoarthritis in 2024\u2013More Hype-AOSSM.   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