{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:53:00Z","timestamp":1790603580265,"version":"4.1.0"},"reference-count":21,"publisher":"American Animal Hospital Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Animal Hospital Association"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:p>\n                    This report examines the effectiveness of clindamycin for the treatment of babesiosis in dogs (n=10) experimentally infected with\n                    <jats:italic>Babesia gibsoni<\/jats:italic>\n                    (\n                    <jats:italic>B. gibsoni<\/jats:italic>\n                    ). Clindamycin (25 mg\/kg body weight, per os,\n                    <jats:italic>q<\/jats:italic>\n                    12 hours for 14 days) gradually reduced parasitemia levels and induced morphological changes that indicated degeneration of parasites (e.g., segmentation; size reduction; localization in the cell limbic and\/or torn state of the nucleus; and swelling, decrease, or disappearance of the cytoplasm) in the majority of dogs. Clindamycin treatment reduced the clinical symptoms characteristic of\n                    <jats:italic>Babesia<\/jats:italic>\n                    infection, including anemia, anorexia, and listlessness. Clindamycin might be useful as a medicine for treatment of\n                    <jats:italic>B. gibsoni<\/jats:italic>\n                    infection.\n                  <\/jats:p>","DOI":"10.5326\/0390558","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T12:22:28Z","timestamp":1410783748000},"page":"558-562","source":"Crossref","is-referenced-by-count":39,"title":["Clindamycin in the Treatment of Babesia gibsoni Infections in Dogs"],"prefix":"10.5326","volume":"39","author":[{"given":"Retno","family":"Wulansari","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agus","family":"Wijaya","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Ano","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichiro","family":"Horii","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Nasu","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-ichi","family":"Yamane","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Makimura","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine (Wulansari, Wijaya, Ano, Horii, Makimura); the Laboratory of Veterinary Anatomy (Nasu); Division of Fisheries (Yamane), Faculty of Agriculture; Miyazaki University, Miyazaki-shi, 889-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"key":"R1","series-title":"J Vet Med Sci","first-page":"1081","volume":"54","year":"1992","unstructured":"Adachi K, Yoshimoto A, Hasegawa T, Shimizu T, Goto Y, Makimura S. 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