{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:49:02Z","timestamp":1770220142448,"version":"3.49.0"},"reference-count":28,"publisher":"American Animal Hospital Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Animal Hospital Association"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>This report describes the diagnostic evaluation of a 7-month-old, female Maltese dog with elevated liver enzymes. Marked elevations of alanine transferase were the significant clinical findings. A diagnosis of gallbladder agenesis was made, based on lack of a gallbladder on ultrasonography and on surgical exploration. Gallbladder agenesis is a rare condition described in humans but not previously reported in dogs.<\/jats:p>","DOI":"10.5326\/0420308","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T12:17:10Z","timestamp":1410783430000},"page":"308-311","source":"Crossref","is-referenced-by-count":17,"title":["Gallbladder Agenesis in a Maltese Dog"],"prefix":"10.5326","volume":"42","author":[{"given":"Brenda","family":"Austin","sequence":"first","affiliation":[{"name":"Departments of Clinical Sciences (Austin, Tillson) and Pathobiology (Kuhnt), College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Michael","family":"Tillson","sequence":"additional","affiliation":[{"name":"Departments of Clinical Sciences (Austin, Tillson) and Pathobiology (Kuhnt), College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leah Ann","family":"Kuhnt","sequence":"additional","affiliation":[{"name":"Departments of Clinical Sciences (Austin, Tillson) and Pathobiology (Kuhnt), College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"R1","series-title":"South Med J","first-page":"914","volume":"93","year":"2000","unstructured":"Baltazar U, Dunn J, Gonzalez-Diaz S, et al. Agenesis of the gallbladder.\n          South Med J\n          2000;93:914\u2013915."},{"key":"R2","year":"1999","unstructured":"Willard MD, Twedt D. Gastrointestinal, pancreatic, and hepatic disorders. In: Willard MD, Tvedten H, Turnwald GH, eds. Small Animal Clinical Diagnosis by Laboratory Methods. 3rd ed. Philadelphia: WB Saunders,\n          1999:172\u2013207."},{"key":"R3","year":"2000","unstructured":"Leveille-Webster CR. Laboratory diagnosis of hepatobiliary disease. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine. 5th ed. Philadelphia: WB Saunders,\n          2000:1277\u20131293."},{"key":"R4","series-title":"Acta Chir Belg","first-page":"347","volume":"104","year":"2004","unstructured":"Trompetas V, Panagopoulos E, Ramantanis G. Gall-bladder agenesis presenting with obstructive jaundice and elevated CA 19-9.\n          Acta Chir Belg\n          2004;104:347\u2013349."},{"key":"R5","series-title":"Swiss Surg","first-page":"315","volume":"9","year":"2003","unstructured":"Peloponissios N, Gillet M, Halkic N. Age\u0301ne\u0301sie de la ve\u0301sicule biliaire [Agenesis of the gallbladder].\n          Swiss Surg\n          2003;9:315\u2013319."},{"key":"R6","series-title":"Acta Gastroenterol Latinoam","first-page":"99","volume":"33","year":"2003","unstructured":"Usandivaras JR, Noguera MA. Agenesia de la vesi\u0301cula biliar [Agenesis of the gallbladder].\n          Acta Gastroenterol Latinoam\n          2003;33:99\u2013102."},{"key":"R7","series-title":"Tidsskr Nor Laegeforen","first-page":"2774","volume":"122","year":"2002","unstructured":"Aspevik RK, Hjelseth B, Irtun O. Gallebl\u00e6reagenesi [Agenesis of the gallbladder].\n          Tidsskr Nor Laegeforen\n          2002;122:2774\u20132776."},{"key":"R8","series-title":"Rev Esp Enferm Dig","first-page":"286","volume":"94","year":"2002","unstructured":"Fernandez Garcia LF, Blanco Fernandez G, Parraga del Moral J, et al. Agenesis of the gallbladder confirmed by nuclear magnetic resonance cholangiogram.\n          Rev Esp Enferm Dig\n          2002;94:286\u2013289."},{"key":"R9","series-title":"Clin Anat","first-page":"167","volume":"14","year":"2001","unstructured":"Lamah M, Karanjia ND, Dickson GH. Anatomical variations of the extrahepatic biliary tree: review of the world literature.\n          Clin Anat\n          2001;14:167\u2013172."},{"key":"R10","series-title":"J Pediatr Surg","first-page":"107","volume":"39","year":"2004","unstructured":"Bittmann S, Ulus H, Springer A. Combined pentalogy of Cantrell with tetralogy of Fallot, gallbladder agenesis, and polysplenia: a case report.\n          J Pediatr Surg\n          2004;39:107\u2013109."},{"key":"R11","series-title":"J Pediatr Surg","first-page":"1","volume":"39","year":"2004","unstructured":"Demircan M, Uguralp S, Mutus M, et al. Teratoma arising from anomalous common bile ducts: a case report.\n          J Pediatr Surg\n          2004;39:1\u20132."},{"key":"R12","series-title":"Arch Surg","first-page":"1257","volume":"123","year":"1988","unstructured":"Bennion R, Thompson JJ, Tompkins R. Agenesis of the gallbladder without extrahepatic biliary atresia.\n          Arch Surg\n          1988;123:1257\u20131260."},{"key":"R13","series-title":"J Clin Gastroenterol","first-page":"231","volume":"16","year":"1993","unstructured":"Richards RJ, Taubin H, Wasson D. Agenesis of the gallbladder in symptomatic adults. A case and review of the literature.\n          J Clin Gastroenterol\n          1993;16:231\u2013233."},{"key":"R14","series-title":"Trop Gastroenterol","first-page":"80","volume":"22","year":"2001","unstructured":"Jain BK, Das DN, Singh RK, et al. Agenesis of gallbladder in symptomatic patients.\n          Trop Gastroenterol\n          2001;22:80\u201382."},{"key":"R15","series-title":"Surg Endosc","first-page":"757","volume":"15","year":"2001","unstructured":"Orlando R, Candiani F, Lirussi F. Agenesis of the gallbladder associated with Gilbert\u2019s syndrome.\n          Surg Endosc\n          2001;15:757."},{"key":"R16","series-title":"J Small Anim Pract","first-page":"27","volume":"41","year":"2000","unstructured":"Schulze C, Rothuizen J, van Sluijs FJ, et al. Extrahepatic biliary atresia in a border collie.\n          J Small Anim Pract\n          2000;41:27\u201330."},{"key":"R17","series-title":"J Small Anim Pract","first-page":"39","volume":"28","year":"1987","unstructured":"Hampson EC, Williams JF. 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