{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:28:09Z","timestamp":1787498889553,"version":"build-2736575974"},"reference-count":38,"publisher":"American Animal Hospital Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of the American Animal Hospital Association"],"published-print":{"date-parts":[[2009]]},"abstract":"<jats:p>A 4-year-old, spayed female, mixed-breed dog was presented for evaluation of chronic left hind-limb lameness. Lytic lesions were observed in the left patella on radiographs of the stifle. A biopsy of the patella led to a histopathological diagnosis of blastomycosis. Surgical debridement followed by a 90-day course of itraconazole and physical rehabilitation resolved the clinical signs and stopped the progression of radiographic lesions. Blastomycosis should be considered as a differential diagnosis for stifle joint lameness with lytic lesions in the patella.<\/jats:p>","DOI":"10.5326\/0450239","type":"journal-article","created":{"date-parts":[[2014,9,15]],"date-time":"2014-09-15T12:08:03Z","timestamp":1410782883000},"page":"239-244","source":"Crossref","is-referenced-by-count":4,"title":["Patellar Blastomycosis in a Dog"],"prefix":"10.5326","volume":"45","author":[{"given":"Abimbola","family":"Oshin","sequence":"first","affiliation":[{"name":"Department of Small Animal Surgery (Oshin), Affiliated Veterinary Specialists, 1668 Mallory Lane, Brentwood, Tennessee 37027; the"},{"name":"Department of Veterinary Clinical Medicine (Griffon) and the Veterinary Diagnostic Laboratory (Barger), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 1008 West Hazelwood Drive, Urbana, Illinois 61802"},{"name":"Laboratoire Vet Diagnostics (Lemberger), 60 Avenue Rockefeller, Lyon, 69008 France; and the"},{"name":"Department of Veterinary Clinical Sciences (Naughton), School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47906"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Griffon","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery (Oshin), Affiliated Veterinary Specialists, 1668 Mallory Lane, Brentwood, Tennessee 37027; the"},{"name":"Department of Veterinary Clinical Medicine (Griffon) and the Veterinary Diagnostic Laboratory (Barger), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 1008 West Hazelwood Drive, Urbana, Illinois 61802"},{"name":"Laboratoire Vet Diagnostics (Lemberger), 60 Avenue Rockefeller, Lyon, 69008 France; and the"},{"name":"Department of Veterinary Clinical Sciences (Naughton), School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47906"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Lemberger","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery (Oshin), Affiliated Veterinary Specialists, 1668 Mallory Lane, Brentwood, Tennessee 37027; the"},{"name":"Department of Veterinary Clinical Medicine (Griffon) and the Veterinary Diagnostic Laboratory (Barger), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 1008 West Hazelwood Drive, Urbana, Illinois 61802"},{"name":"Laboratoire Vet Diagnostics (Lemberger), 60 Avenue Rockefeller, Lyon, 69008 France; and the"},{"name":"Department of Veterinary Clinical Sciences (Naughton), School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47906"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Naughton","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery (Oshin), Affiliated Veterinary Specialists, 1668 Mallory Lane, Brentwood, Tennessee 37027; the"},{"name":"Department of Veterinary Clinical Medicine (Griffon) and the Veterinary Diagnostic Laboratory (Barger), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 1008 West Hazelwood Drive, Urbana, Illinois 61802"},{"name":"Laboratoire Vet Diagnostics (Lemberger), 60 Avenue Rockefeller, Lyon, 69008 France; and the"},{"name":"Department of Veterinary Clinical Sciences (Naughton), School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47906"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Barger","sequence":"additional","affiliation":[{"name":"Department of Small Animal Surgery (Oshin), Affiliated Veterinary Specialists, 1668 Mallory Lane, Brentwood, Tennessee 37027; the"},{"name":"Department of Veterinary Clinical Medicine (Griffon) and the Veterinary Diagnostic Laboratory (Barger), College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 1008 West Hazelwood Drive, Urbana, Illinois 61802"},{"name":"Laboratoire Vet Diagnostics (Lemberger), 60 Avenue Rockefeller, Lyon, 69008 France; and the"},{"name":"Department of Veterinary Clinical Sciences (Naughton), School of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, Indiana 47906"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"key":"R1","series-title":"Vet Clin North Am Small Anim Pract","first-page":"855","volume":"23","year":"1993","unstructured":"Roush JK. Canine patellar luxation.\n          Vet Clin North Am Small Anim Pract\n          1993;23:855\u2013868."},{"key":"R2","series-title":"Vet Clin North Am Small Anim Pract","first-page":"877","volume":"23","year":"1993","unstructured":"McLaughlin R Jr. Intra-articular stifle fractures and arthrodesis.\n          Vet Clin North Am Small Anim Pract\n          1993;23:877\u2013895."},{"key":"R3","series-title":"J Am Vet Med Assoc","first-page":"2082","volume":"209","year":"1996","unstructured":"Gee M, Lenehan TM, Tarvin GB. Rotatory intra-articular dislocation of the patella in two dogs.\n          J Am Vet Med Assoc\n          1996;209: 2082\u20132084."},{"key":"R4","series-title":"J Am Vet Med Assoc","first-page":"165","volume":"187","year":"1985","unstructured":"Thacher C, Schrader SC, Liu SK. Osteosarcoma of the patella in a dog.\n          J Am Vet Med Assoc\n          1985;187:165\u2013167."},{"key":"R5","series-title":"Vet Radiol Ultrasound","first-page":"218","volume":"42","year":"2001","unstructured":"Lucroy MD, Peck JN, Berry CR. Osteosarcoma of the patella with pulmonary metastases in a dog.\n          Vet Radiol Ultrasound\n          2001;42: 218\u2013220."},{"key":"R6","series-title":"J Am Anim Hosp Assoc","first-page":"165","volume":"38","year":"2002","unstructured":"Lahmers SM, Mealey KL, Martinez SA, Haldorson GJ, Sellon RK, Cambridge AJ. Synovial T-cell lymphoma of the stifle in a dog.\n          J Am Anim Hosp Assoc\n          2002;38:165\u2013168."},{"key":"R7","year":"1985","unstructured":"Nunamaker D. Osteomyelitis. In: Newton C, Nunamker D, eds. Textbook of Small Animal Orthopedics. Philadelphia: JB Lippincott,\n          1985:499."},{"key":"R8","year":"1985","unstructured":"Daly W. Orthopedic infections. In: Slatter D, ed. Textbook of Small Animal Surgery. Philadelphia: WB Saunders,\n          1985:2020."},{"key":"R9","series-title":"J Am Vet Med Assoc","first-page":"1292","volume":"190","year":"1987","unstructured":"Archer JR, Trainer DO, Schell RF. Epidemiologic study of canine blastomycosis in Wisconsin.\n          J Am Vet Med Assoc\n          1987;190: 1292\u20131295."},{"key":"R10","series-title":"J Am Vet Med Assoc","first-page":"1754","volume":"201","year":"1992","unstructured":"Rudmann DG, Coolman BR, Perez CM, Glickman LT. Evaluation of risk factors for blastomycosis in dogs: 857 cases (1980\u20131990).\n          J Am Vet Med Assoc\n          1992;201:1754\u20131759."},{"key":"R11","series-title":"Semin Respir Infect","first-page":"29","volume":"1","year":"1986","unstructured":"Klein BS, Vergeront JM, Davis JP. Epidemiologic aspects of blastomycosis, the enigmatic systemic mycosis.\n          Semin Respir Infect\n          1986;1:29\u201339."},{"key":"R12","series-title":"Sabouraudia","first-page":"188","volume":"12","year":"1974","unstructured":"Turner C, Furcolow ML, Smith CD. Experimental histoplasmosis and blastomycosis in young pups.\n          Sabouraudia\n          1974;12:188\u2013192."},{"key":"R13","series-title":"J Am Vet Med Assoc","first-page":"1163","volume":"178","year":"1981","unstructured":"Legendre AM, Walker M, Buyukmihci N, Stevens R. Canine blastomycosis: a review of 47 clinical cases.\n          J Am Vet Med Assoc\n          1981;178:1163\u20131168."},{"key":"R14","series-title":"Northwest Med","first-page":"255","volume":"54","year":"1955","unstructured":"Scott MJ. Cutaneous blastomycosis; report of case following dog bite.\n          Northwest Med\n          1955;54:255\u2013257."},{"key":"R15","series-title":"Am J Clin Pathol","first-page":"253","volume":"79","year":"1983","unstructured":"Larson DM, Eckman MR, Alber RL, Goldschmidt VG. Primary cutaneous (inoculation) blastomycosis: an occupational hazard to pathologists.\n          Am J Clin Pathol\n          1983;79:253\u2013255."},{"key":"R16","series-title":"Ann Intern Med","first-page":"48","volume":"98","year":"1983","unstructured":"Gnann JW Jr., Bressler GS, Bodet CA 3rd, Avent CK. Human blastomycosis after a dog bite.\n          Ann Intern Med\n          1983;98:48\u201349."},{"key":"R17","series-title":"Clin Infect Dis","first-page":"E44","volume":"34","year":"2002","unstructured":"Gray NA, Baddour LM. Cutaneous inoculation blastomycosis.\n          Clin Infect Dis\n          2002;34:E44\u201349."},{"key":"R18","series-title":"J Am Vet Med Assoc","first-page":"1877","volume":"209","year":"1996","unstructured":"Marcellin-Little DJ, Sellon RK, Kyles AE, Lemons CL, Kaufman L. Chronic localized osteomyelitis caused by atypical infection with Blastomyces dermatitidis in a dog.\n          J Am Vet Med Assoc\n          1996;209:1877\u20131879."},{"key":"R19","series-title":"Vet Radiol","first-page":"124","volume":"20","year":"1979","unstructured":"Roberts RE. Osteomyelitis associated with disseminated blastomycosis in nine dogs.\n          Vet Radiol\n          1979;20:124\u2013134."},{"key":"R20","year":"2004","unstructured":"Taboada J, Grooters AM. Systemic mycosis. In: Ettinger SJ, Feldman EC, eds. Textbook of Veterinary Internal Medicine. 6th ed. Philadelphia: WB Saunders,\n          2004:671\u2013690."},{"key":"R21","year":"1998","unstructured":"Legendre AM. Blastomycosis. In: Green CE, ed. Clinical microbiology and infectious diseases of the dog and cat. Philadelphia: WB Saunders,\n          1998:371\u2013377."},{"key":"R22","series-title":"J Am Vet Med Assoc","first-page":"479","volume":"210","year":"1997","unstructured":"Cote E, Barr SC, Allen C. Possible transmission of blastomycosis dermatitidis via culture specimen.\n          J Am Vet Med Assoc\n          1997;210:479\u2013480."},{"key":"R23","series-title":"J Am Vet Med Assoc","first-page":"222","volume":"232","year":"2008","unstructured":"Crews LJ, Feeney DA, Jessen CR, Newman AB, Sharkey LC. Utility of diagnostic tests for and medical treatment of pulmonary blastomycosis in dogs: 125 cases (1989\u20132006).\n          J Am Vet Med Assoc\n          2008;232:222\u2013227."},{"key":"R24","series-title":"Am J Vet Res","first-page":"554","volume":"61","year":"2000","unstructured":"Klein BS, Squires RA, Lloyd JK, Ruge DR, Legendre AM. Canine antibody response to Blastomyces dermatitidis WI-1 antigen.\n          Am J Vet Res\n          2000;61:554\u2013558."},{"key":"R25","series-title":"J Am Vet Med Assoc","first-page":"658","volume":"213","year":"1998","unstructured":"Arceneaux KA, Taboada J, Hosgood G. Blastomycosis in dogs: 115 cases (1980\u20131995).\n          J Am Vet Med Assoc\n          1998;213:658\u2013664."},{"key":"R26","series-title":"Am J Vet Res","first-page":"2109","volume":"41","year":"1980","unstructured":"Legendre AM, Becker PU. Evaluation of the agar-gel immunodiffusion test in the diagnosis of canine blastomycosis.\n          Am J Vet Res\n          1980;41:2109\u20132111."},{"key":"R27","series-title":"J Vet Intern Med","first-page":"839","volume":"22","year":"2008","unstructured":"Spector D, Legendre AM, Wheat J, et al. Antigen and antibody testing for the diagnosis of blastomycosis in dogs.\n          J Vet Intern Med\n          2008;22:839\u2013843."},{"key":"R28","series-title":"J Am Vet Med Assoc","first-page":"2073","volume":"209","year":"1996","unstructured":"Krawiec DR, McKiernan BC, Twardock AR, et al. Use of an amphotericin B lipid complex for treatment of blastomycosis in dogs.\n          J Am Vet Med Assoc\n          1996;209:2073\u20132075."},{"key":"R29","series-title":"J Am Vet Med Assoc","first-page":"1249","volume":"184","year":"1984","unstructured":"Legendre AM, Selcer BA, Edwards DF, Stevens R. Treatment of canine blastomycosis with amphotericin B and ketoconazole.\n          J Am Vet Med Assoc\n          1984;184:1249\u20131254."},{"key":"R30","series-title":"J Am Vet Med Assoc","first-page":"156","volume":"182","year":"1983","unstructured":"Dunbar M Jr., Pyle RL, Boring JG, McCoy CP. Treatment of canine blastomycosis with ketoconazole.\n          J Am Vet Med Assoc\n          1983;182:156\u2013157."},{"key":"R31","series-title":"Res Vet Sci","first-page":"372","volume":"57","year":"1994","unstructured":"Craig AJ, Ramzan I, Malik R. Pharmacokinetics of fluconazole in cats after intravenous and oral administration.\n          Res Vet Sci\n          1994;57:372\u2013376."},{"key":"R32","series-title":"Vet Clin North Am Small Anim Pract","first-page":"749","volume":"33","year":"2003","unstructured":"Grooters AM, Taboada J. Update on antifungal therapy.\n          Vet Clin North Am Small Anim Pract\n          2003;33:749\u2013758, vi."},{"key":"R33","series-title":"Vet Ophthalmol","first-page":"299","volume":"10","year":"2007","unstructured":"Finn MJ, Stiles J, Krohne SG. Visual outcome in a group of dogs with ocular blastomycosis treated with systemic antifungals and systemic corticosteroids.\n          Vet Ophthalmol\n          2007;10:299\u2013303."},{"key":"R34","series-title":"J Am Vet Med Assoc","first-page":"1210","volume":"231","year":"2007","unstructured":"Smith JR, Legendre AM, Thomas WB, et al. Cerebral Blastomyces dermatitidis infection in a cat.\n          J Am Vet Med Assoc\n          2007;231; 1210\u20131214."},{"key":"R35","series-title":"Clin Tech Small Anim Pract","first-page":"240","volume":"20","year":"2005","unstructured":"Hector RF. An overview of antifungal drugs and their use for treatment of deep and superficial mycoses in animals.\n          Clin Tech Small Anim Pract\n          2005;20:240\u2013249."},{"key":"R36","series-title":"J Vet Intern Med","first-page":"365","volume":"10","year":"1996","unstructured":"Legendre AM, Rohrbach BW, Toal RL, Rinaldi MG, Grace LL, Jones JB. Treatment of blastomycosis with itraconazole in 112 dogs.\n          J Vet Intern Med\n          1996;10:365\u2013371."},{"key":"R37","series-title":"Prog Vet Compar Ophthalmol","first-page":"263","volume":"4","year":"1991","unstructured":"Brooks DE, Legendre AM, Gum GC, et al. The treatment of ocular blastomycosis with systemically administered itraconazole.\n          Prog Vet Compar Ophthalmol\n          1991;4:263\u2013268."},{"key":"R38","series-title":"Antimicrob Agents Chemother","first-page":"978","volume":"42","year":"1998","unstructured":"Chapman SW, Rogers PD, Rinaldi MG, Sullivan DC. Susceptibilities of clinical and laboratory isolates of Blastomyces dermatitidis to ketoconazole, itraconazole, and fluconazole.\n          Antimicrob Agents Chemother\n          1998;42:978\u2013980."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/45\/5\/article-p239.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/45\/5\/239\/1333611\/0450239.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/45\/5\/article-p239.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/45\/5\/article-p239.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T15:55:47Z","timestamp":1763740547000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/45\/5\/article-p239.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":38,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.5326\/0450239","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}