{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:53:55Z","timestamp":1791266035484,"version":"4.1.0"},"reference-count":18,"publisher":"American Animal Hospital Association","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>\n                    A 4 yr old, spayed female domestic shorthair was referred with a 2 mo history of weight loss, anorexia, and diarrhea. Skin fragility was noted on presentation and a large skin tear measuring 5 cm \u00d7 5 cm was obvious over the dorsal cervical region. The patient was previously treated with short-term prednisone that was discontinued 6 wk before presentation. Initial diagnostics (complete blood count and biochemistry) did not indicate an endocrine disorder, the most common cause of acquired feline skin fragility. Necropsy revealed diffuse histoplasmosis (most significantly affecting the skin), epidermal atrophy, dermal collagen separation, and infiltration in the dermis and subcutis by inflammatory cells containing yeast organisms consistent with\n                    <jats:italic>Histoplasma<\/jats:italic>\n                    spp. Infiltrative fungal infection should be considered as a potential cause of acquired feline skin fragility.\n                  <\/jats:p>","DOI":"10.5326\/jaaha-ms-5517","type":"journal-article","created":{"date-parts":[[2011,4,16]],"date-time":"2011-04-16T03:30:13Z","timestamp":1302924613000},"page":"e36-e41","source":"Crossref","is-referenced-by-count":18,"title":["Disseminated Histoplasmosis Accompanied by Cutaneous Fragility in a Cat"],"prefix":"10.5326","volume":"47","author":[{"given":"Amy M.","family":"Tamulevicus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Harkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyathanahalli","family":"Janardhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad M.","family":"Debey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"6","key":"bib1","series-title":"Vet Pathol","first-page":"603","article-title":"Collagen dysplasia (cutaneous asthenia) in a cat","volume":"36","author":"Sequeira","year":"1999","unstructured":"Sequeira\n              JL\n            , RochaNS, BandarraEP. Collagen dysplasia (cutaneous asthenia) in a cat. Vet Pathol1999;36(6):603\u20136."},{"issue":"5","key":"bib2","series-title":"J Am Vet Med Assoc","first-page":"698, 706","article-title":"Diaphragmatic and perineal hernias associated with cutaneous asthenia in a cat","volume":"224","author":"Benitah","year":"2004","unstructured":"Benitah\n              N\n            , MatousekJL, BarnesRF. Diaphragmatic and perineal hernias associated with cutaneous asthenia in a cat. J Am Vet Med Assoc2004;224(5):698, 706\u20139."},{"issue":"6","key":"bib3","series-title":"Vet Pathol","first-page":"616","article-title":"Reduced anchoring fibril formation and collagen VII immunoreactivity in feline dystrophic epidermolysis bullosa","volume":"36","author":"Olivry","year":"1999","unstructured":"Olivry\n              T\n            , DunstonSM, MarinkovichMP. Reduced anchoring fibril formation and collagen VII immunoreactivity in feline dystrophic epidermolysis bullosa. 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