{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:24:34Z","timestamp":1791285874510,"version":"4.1.0"},"reference-count":84,"publisher":"American Animal Hospital Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"abstract":"\n Eighteen clinically ill dogs, naturally infected with\n Anaplasma phagocytophilum,<\/jats:italic>\n were examined at a veterinary practice in Baxter, Minnesota. A clinical examination, complete blood cell count, enzyme- linked immunosorbent assay (ELISA) for\n A phagocytophilum, Borrelia burgdorferi,<\/jats:italic>\n and\n Ehrlichia canis<\/jats:italic>\n antibodies and\n Dirofilaria immitis<\/jats:italic>\n antigen, and a polymerase chain reaction test for\n A phagocytophilum<\/jats:italic>\n DNA were obtained for all dogs. Physical examination findings included fever, arthropathy, lymphadenopathy, epistaxis, acute gastritis, cervical hyperpathia, and central nervous system dysfunction. Complete blood cell count abnormalities included thrombocytopenia, morulae in neutrophils, anemia, leukopenia, eosinopenia, lymphopenia, and monocytosis. Seroreactivity to\n A phagocytophilum<\/jats:italic>\n was found in 61%,\n B burgdorfer<\/jats:italic>\n i antibodies in 17%, and\n D immitis<\/jats:italic>\n antigen in 5% of the dogs. Fever, arthropathy, neurologic dysfunction, and epistaxis are clinical syndromes that can be associated with\n A phagocytophilum<\/jats:italic>\n infection. Treatment with doxycycline resulted in rapid resolution of clinical signs in all dogs.\n <\/jats:p>","DOI":"10.5326\/jaaha-ms-5578","type":"journal-article","created":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T12:29:53Z","timestamp":1320409793000},"page":"e86-e94","source":"Crossref","is-referenced-by-count":42,"title":["Typical and Atypical Manifestations of Anaplasma phagocytophilum Infection in Dogs"],"prefix":"10.5326","volume":"47","author":[{"given":"Matthew D.","family":"Eberts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Paulo","family":"Vissotto de Paiva Diniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa J.","family":"Beall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett A.","family":"Stillman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramaswamy","family":"Chandrashekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward B.","family":"Breitschwerdt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"12","key":"bib1","series-title":"J Am Vet Med Assoc","first-page":"1750","article-title":"Ehrlichiosis and related infections","volume":"223","author":"McQuiston","year":"2003","unstructured":"McQuiston\n JH\n , McCallCL, NicholsonWL. 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