{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:44:12Z","timestamp":1787031852676,"version":"build-2736575974"},"reference-count":22,"publisher":"American Animal Hospital Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>The objective of this retrospective study was to evaluate the presence of concurrent splenic and cardiac hemangiosarcoma (HSA). Dogs were divided into two groups: group 1 included 23 dogs with splenic HSA, and group 2 included 31 dogs with a cardiac HSA. All dogs were fully assessed for metastasis with thoracic radiography, abdominal and\/or cardiac ultrasound, and\/or postmortem examination. Two dogs (8.7%) in group 1 had a concurrent cardiac mass. Neither of these dogs had pericardial effusion, and both were golden retrievers. Thirteen of the dogs in group 1 presented with a hemoabdomen. Concurrent intra-abdominal metastasis was noted in seven dogs. In group 2, 9\/31 (29%) of the dogs had a concurrent splenic HSA, and 13\/31 (42%) of the dogs had evidence of metastasis to another site. There was a significant association between age and the presence of nonsplenic metastasis (odds ratio, 0.457). The rate of concurrent right atrial mass detected by cardiac ultrasound in dogs with splenic HSA was 8.7%, which is less than previously reported. For dogs with right atrial HSA, the risk of metastasis to nonsplenic sites decreases with age.<\/jats:p>","DOI":"10.5326\/jaaha-ms-5603","type":"journal-article","created":{"date-parts":[[2011,8,19]],"date-time":"2011-08-19T00:31:55Z","timestamp":1313713915000},"page":"336-341","source":"Crossref","is-referenced-by-count":47,"title":["Concurrent Splenic and Right Atrial Mass at Presentation in Dogs with HSA: A Retrospective Study"],"prefix":"10.5326","volume":"47","author":[{"given":"Sarah E.","family":"Boston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Higginson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Monteith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"7","key":"bib1","series-title":"Exp Hematol","first-page":"870","article-title":"Canine HSA originates from hematopoietic precursors with potential for endothelial differentiation","volume":"34","author":"Lamerato-Kozicki","year":"2006","unstructured":"Lamerato-Kozicki\n              AR\n            , HelmKM, JubalaCM. Canine HSA originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol2006;34(7):870\u20138."},{"issue":"5","key":"bib2","series-title":"J Am Anim Hosp Assoc","first-page":"417","article-title":"Prognosis for dogs with stage I or II splenic HSA treated by splenectomy alone: 32 cases (1991\u20131993)","volume":"34","author":"Wood","year":"1998","unstructured":"Wood\n              CA\n            , MooreAS, GliattoJM. Prognosis for dogs with stage I or II splenic HSA treated by splenectomy alone: 32 cases (1991\u20131993). J Am Anim Hosp Assoc1998;34(5):417\u201321."},{"key":"bib3","series-title":"Small animal clinical oncology","first-page":"785","article-title":"Miscellaneous tumors","author":"Thamm","year":"2007","unstructured":"Thamm\n              DH\n            \n          . Miscellaneous tumors. In: WithrowSJ, VailDM, eds. Small animal clinical oncology. 4th ed. St. Louis (MO): Saunders; 2007:785\u201395."},{"key":"bib4","series-title":"J Small Anim Pract","first-page":"805","article-title":"Metastatic pattern in dogs with splenic haemangiosarcoma: clinical implications","volume":"29","author":"Waters","year":"1988","unstructured":"Waters\n              DJ\n            , CaywoodDD, HaydenDW. Metastatic pattern in dogs with splenic haemangiosarcoma: clinical implications. J Small Anim Pract1988;29:805\u201314."},{"issue":"5","key":"bib5","series-title":"J Vet Intern Med","first-page":"479","article-title":"Treatment of canine HSA: 2000 and beyond","volume":"14","author":"Clifford","year":"2000","unstructured":"Clifford\n              CA\n            , MackinAJ, HenryCJ. Treatment of canine HSA: 2000 and beyond. J Vet Intern Med2000;14(5):479\u201385."},{"key":"bib6","series-title":"Compend Contin Educ Pract Vet","first-page":"1065","volume":"13","author":"Hosgood","year":"1991","unstructured":"Hosgood\n              G\n            , CanineHSA. Compend Contin Educ Pract Vet1991;13:1065\u201375."},{"key":"bib7","series-title":"Vet Med","first-page":"188","article-title":"Diagnosing and treating canine HSA","volume":"87","author":"Hammer","year":"1992","unstructured":"Hammer\n              AS\n            , CoutoCG. Diagnosing and treating canine HSA. Vet Med1992;87:188\u2013201."},{"issue":"4","key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"575","article-title":"Survival times in dogs with right atrial HSA treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986\u20132000)","volume":"226","author":"Weisse","year":"2005","unstructured":"Weisse\n              C\n            , SoaresN, BealMW. Survival times in dogs with right atrial HSA treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986\u20132000). J Am Vet Med Assoc2005;226(4):575\u20139."},{"issue":"3","key":"bib9","series-title":"J Vet Intern Med","first-page":"160","article-title":"Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy","volume":"3","author":"Johnson","year":"1989","unstructured":"Johnson\n              KA\n            , PowersBE, WithrowSJ. Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy. J Vet Intern Med1989;3(3):160\u20136."},{"issue":"10","key":"bib10","series-title":"J Am Vet Med Assoc","first-page":"1550","article-title":"Epirubicin in the adjuvant treatment of splenic HSA in dogs: 59 cases (1997\u20132004)","volume":"231","author":"Kim","year":"2007","unstructured":"Kim\n              SE\n            , LiptakJM, GallTT. Epirubicin in the adjuvant treatment of splenic HSA in dogs: 59 cases (1997\u20132004). J Am Vet Med Assoc2007;231(10):1550\u20137."},{"key":"bib11","series-title":"Small animal clinical oncology","first-page":"31","article-title":"Tumor biology and metastasis","author":"Argyle","year":"2007","unstructured":"Argyle\n              DJ\n            , KhannaC. Tumor biology and metastasis. In: WithrowSJ, VailDM, eds. Small animal clinical oncology. 4th ed. St. Louis (MO): Saunders; 2007:31\u201353."},{"issue":"7","key":"bib1","series-title":"Exp Hematol","first-page":"870","article-title":"Canine HSA originates from hematopoietic precursors with potential for endothelial differentiation","volume":"34","author":"Lamerato-Kozicki","year":"2006","unstructured":"Lamerato-Kozicki\n              AR\n            , HelmKM, JubalaCM. Canine HSA originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol2006;34(7):870\u20138."},{"issue":"5","key":"bib2","series-title":"J Am Anim Hosp Assoc","first-page":"417","article-title":"Prognosis for dogs with stage I or II splenic HSA treated by splenectomy alone: 32 cases (1991\u20131993)","volume":"34","author":"Wood","year":"1998","unstructured":"Wood\n              CA\n            , MooreAS, GliattoJM. Prognosis for dogs with stage I or II splenic HSA treated by splenectomy alone: 32 cases (1991\u20131993). J Am Anim Hosp Assoc1998;34(5):417\u201321."},{"key":"bib3","series-title":"Small animal clinical oncology","first-page":"785","article-title":"Miscellaneous tumors","author":"Thamm","year":"2007","unstructured":"Thamm\n              DH\n            \n          . Miscellaneous tumors. In: WithrowSJ, VailDM, eds. Small animal clinical oncology. 4th ed. St. Louis (MO): Saunders; 2007:785\u201395."},{"key":"bib4","series-title":"J Small Anim Pract","first-page":"805","article-title":"Metastatic pattern in dogs with splenic haemangiosarcoma: clinical implications","volume":"29","author":"Waters","year":"1988","unstructured":"Waters\n              DJ\n            , CaywoodDD, HaydenDW. Metastatic pattern in dogs with splenic haemangiosarcoma: clinical implications. J Small Anim Pract1988;29:805\u201314."},{"issue":"5","key":"bib5","series-title":"J Vet Intern Med","first-page":"479","article-title":"Treatment of canine HSA: 2000 and beyond","volume":"14","author":"Clifford","year":"2000","unstructured":"Clifford\n              CA\n            , MackinAJ, HenryCJ. Treatment of canine HSA: 2000 and beyond. J Vet Intern Med2000;14(5):479\u201385."},{"key":"bib6","series-title":"Compend Contin Educ Pract Vet","first-page":"1065","volume":"13","author":"Hosgood","year":"1991","unstructured":"Hosgood\n              G\n            , CanineHSA. Compend Contin Educ Pract Vet1991;13:1065\u201375."},{"key":"bib7","series-title":"Vet Med","first-page":"188","article-title":"Diagnosing and treating canine HSA","volume":"87","author":"Hammer","year":"1992","unstructured":"Hammer\n              AS\n            , CoutoCG. Diagnosing and treating canine HSA. Vet Med1992;87:188\u2013201."},{"issue":"4","key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"575","article-title":"Survival times in dogs with right atrial HSA treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986\u20132000)","volume":"226","author":"Weisse","year":"2005","unstructured":"Weisse\n              C\n            , SoaresN, BealMW. Survival times in dogs with right atrial HSA treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986\u20132000). J Am Vet Med Assoc2005;226(4):575\u20139."},{"issue":"3","key":"bib9","series-title":"J Vet Intern Med","first-page":"160","article-title":"Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy","volume":"3","author":"Johnson","year":"1989","unstructured":"Johnson\n              KA\n            , PowersBE, WithrowSJ. Splenomegaly in dogs. Predictors of neoplasia and survival after splenectomy. J Vet Intern Med1989;3(3):160\u20136."},{"issue":"10","key":"bib10","series-title":"J Am Vet Med Assoc","first-page":"1550","article-title":"Epirubicin in the adjuvant treatment of splenic HSA in dogs: 59 cases (1997\u20132004)","volume":"231","author":"Kim","year":"2007","unstructured":"Kim\n              SE\n            , LiptakJM, GallTT. Epirubicin in the adjuvant treatment of splenic HSA in dogs: 59 cases (1997\u20132004). J Am Vet Med Assoc2007;231(10):1550\u20137."},{"key":"bib11","series-title":"Small animal clinical oncology","first-page":"31","article-title":"Tumor biology and metastasis","author":"Argyle","year":"2007","unstructured":"Argyle\n              DJ\n            , KhannaC. Tumor biology and metastasis. In: WithrowSJ, VailDM, eds. Small animal clinical oncology. 4th ed. St. Louis (MO): Saunders; 2007:31\u201353."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/47\/5\/article-p336.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/47\/5\/336\/1742651\/jaaha-ms-5603.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/47\/5\/article-p336.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/47\/5\/article-p336.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:30:55Z","timestamp":1772325055000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/47\/5\/article-p336.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"references-count":22,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-5603","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}