{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T01:02:54Z","timestamp":1772326974949,"version":"3.50.1"},"reference-count":24,"publisher":"American Animal Hospital Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"abstract":"<jats:p>Granulomatous sebaceous adenitis (GSA) is uncommon in dogs; however, certain breed predilections exist. In this report, three cases of GSA in unrelated vizslas have been described. All cases initially presented with episodes of otitis externa followed by severe inner pinnal lesions. In one case, multifocal coalescing inner pinnal ulceration appeared 4 wk prior to the occurrence of the skin lesions. The other two cases presented with simultaneous pinnal and skin lesions following episodes of bilateral otitis. The pinnae were diffusely erythematous and had multiple coalescing erosions and ulcers. The body lesions consisted of multifocal alopecia, papules, and fine scales. Biopsies of the skin and pinnae confirmed GSA. Two dogs responded to treatment with synthetic retinoids and cyclosporin A, respectively. One dog was not treated, and the owners preferred euthanasia when the ear lesions recurred and did not respond to glucocorticoids. To the best of the authors\u2019 knowledge, GSA with multifocal coalescing ulcerative pinnal lesions has not previously been reported.<\/jats:p>","DOI":"10.5326\/jaaha-ms-5705","type":"journal-article","created":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T12:29:53Z","timestamp":1320409793000},"page":"455-460","source":"Crossref","is-referenced-by-count":4,"title":["Severe Ulcerative and Granulomatous Pinnal Lesions with Granulomatous Sebaceous Adenitis in Unrelated Vizslas"],"prefix":"10.5326","volume":"47","author":[{"given":"Gila","family":"Zur","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana-Maria","family":"Botero-Anug","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"Muller and Kirk's small animal dermatology","first-page":"1125","article-title":"Miscellaneous skin diseases","author":"Scott","year":"2001","unstructured":"Scott\n              DW\n            , MillerWH, GriffinCE. Miscellaneous skin diseases. In; Muller and Kirk's small animal dermatology. 6th ed.Philadelphia (PA): WB Saunders; 2001:1125\u201383."},{"issue":"1","key":"bib2","series-title":"Vet Clin North Am Small Anim Pract","first-page":"243","article-title":"Sebaceous adenitis","volume":"36","author":"Sousa","year":"2006","unstructured":"Sousa\n              CA\n            \n          . Sebaceous adenitis. Vet Clin North Am Small Anim Pract2006;36(1):243\u20139, ix."},{"issue":"6","key":"bib3","series-title":"Vet Clin North Am Small Anim Pract","first-page":"1603","article-title":"Newly reported skin disease syndromes in the dog","volume":"20","author":"Stewart","year":"1990","unstructured":"Stewart\n              LJ\n            \n          . Newly reported skin disease syndromes in the dog. Vet Clin North Am Small Anim Pract1990;20(6):1603\u201313."},{"issue":"5","key":"bib4","series-title":"Vet Dermatol","first-page":"243","article-title":"Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity","volume":"12","author":"Reichler","year":"2001","unstructured":"Reichler\n              IM\n            , HauserB, SchillerI. Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity. Vet Dermatol2001;12(5):243\u201353."},{"key":"bib5","series-title":"Skin diseases of the dog and cat: clinical and histopathologic diagnosis","first-page":"453","author":"Gross","year":"2005","unstructured":"Gross\n              TL\n            , IhrkePJ, WalderEJ. Skin diseases of the dog and cat: clinical and histopathologic diagnosis. 2nd ed.Oxford (UK): Blackwell Publishing; 2005:453\u20137."},{"issue":"1","key":"bib6","series-title":"Am J Dermatopathol","first-page":"40","article-title":"Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells","volume":"22","author":"Affolter","year":"2000","unstructured":"Affolter\n              VK\n            , MoorePF. Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells. Am J Dermatopathol2000;22(1):40\u20138."},{"issue":"4","key":"bib7","series-title":"Compend Contin Educ Vet","first-page":"202","article-title":"Canine histiocytic diseases","volume":"30","author":"Coomer","year":"2008","unstructured":"Coomer\n              AR\n            , LiptakJM. Canine histiocytic diseases. Compend Contin Educ Vet2008;30(4):202\u20134, 208\u201316 [quiz 216\u20137]."},{"issue":"4","key":"bib8","series-title":"Vet Clin North Am Small Anim Pract","first-page":"731","article-title":"Otitis externa. A disease of multifactorial etiology","volume":"18","author":"August","year":"1988","unstructured":"August\n              JR\n            \n          . Otitis externa. A disease of multifactorial etiology. Vet Clin North Am Small Anim Pract1988;18(4):731\u201342."},{"issue":"2","key":"bib9","series-title":"J Am Vet Med Assoc","first-page":"197","article-title":"Sebaceous adenitis in dogs and results of treatment with isotretinoin and etretinate: 30 cases (1990\u20131994)","volume":"207","author":"White","year":"1995","unstructured":"White\n              SD\n            , RosychukRA, ScottKV. Sebaceous adenitis in dogs and results of treatment with isotretinoin and etretinate: 30 cases (1990\u20131994). J Am Vet Med Assoc1995;207(2):197\u2013200."},{"key":"bib10","series-title":"Muller and Kirk's small animal dermatology","first-page":"667","article-title":"Immune-mediated disorders","author":"Scott","year":"2001","unstructured":"Scott\n              DW\n            , MillerWH, GriffinCE. Immune-mediated disorders. In: Muller and Kirk's small animal dermatology. 6th ed.Philadelphia (PA): WB Saunders; 2001:667\u2013779."},{"key":"bib11","series-title":"Muller and Kirk's small animal dermatology","first-page":"1185","article-title":"Diseases of the eyelids, claws, anal sacs and ears","author":"Scott","year":"2001","unstructured":"Scott\n              DW\n            , MillerWH, GriffinCE. Diseases of the eyelids, claws, anal sacs and ears. In: Muller and Kirk's small animal dermatology. 6th ed.Philadelphia (PA): WB Saunders; 2001:1185\u2013235."},{"issue":"8","key":"bib12","series-title":"J Small Anim Pract","first-page":"350","article-title":"Ulcerative otitis externa responsive to immunosuppressive therapy in two dogs","volume":"43","author":"Hendricks","year":"2002","unstructured":"Hendricks\n              A\n            , BrooksH, PocknellA. Ulcerative otitis externa responsive to immunosuppressive therapy in two dogs. J Small Anim Pract2002;43(8):350\u20134."},{"key":"bib1","series-title":"Muller and Kirk's small animal dermatology","first-page":"1125","article-title":"Miscellaneous skin diseases","author":"Scott","year":"2001","unstructured":"Scott\n              DW\n            , MillerWH, GriffinCE. Miscellaneous skin diseases. In; Muller and Kirk's small animal dermatology. 6th ed.Philadelphia (PA): WB Saunders; 2001:1125\u201383."},{"issue":"1","key":"bib2","series-title":"Vet Clin North Am Small Anim Pract","first-page":"243","article-title":"Sebaceous adenitis","volume":"36","author":"Sousa","year":"2006","unstructured":"Sousa\n              CA\n            \n          . Sebaceous adenitis. Vet Clin North Am Small Anim Pract2006;36(1):243\u20139, ix."},{"issue":"6","key":"bib3","series-title":"Vet Clin North Am Small Anim Pract","first-page":"1603","article-title":"Newly reported skin disease syndromes in the dog","volume":"20","author":"Stewart","year":"1990","unstructured":"Stewart\n              LJ\n            \n          . Newly reported skin disease syndromes in the dog. Vet Clin North Am Small Anim Pract1990;20(6):1603\u201313."},{"issue":"5","key":"bib4","series-title":"Vet Dermatol","first-page":"243","article-title":"Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity","volume":"12","author":"Reichler","year":"2001","unstructured":"Reichler\n              IM\n            , HauserB, SchillerI. Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity. Vet Dermatol2001;12(5):243\u201353."},{"key":"bib5","series-title":"Skin diseases of the dog and cat: clinical and histopathologic diagnosis","first-page":"453","author":"Gross","year":"2005","unstructured":"Gross\n              TL\n            , IhrkePJ, WalderEJ. Skin diseases of the dog and cat: clinical and histopathologic diagnosis. 2nd ed.Oxford (UK): Blackwell Publishing; 2005:453\u20137."},{"issue":"1","key":"bib6","series-title":"Am J Dermatopathol","first-page":"40","article-title":"Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells","volume":"22","author":"Affolter","year":"2000","unstructured":"Affolter\n              VK\n            , MoorePF. Canine cutaneous and systemic histiocytosis: reactive histiocytosis of dermal dendritic cells. Am J Dermatopathol2000;22(1):40\u20138."},{"issue":"4","key":"bib7","series-title":"Compend Contin Educ Vet","first-page":"202","article-title":"Canine histiocytic diseases","volume":"30","author":"Coomer","year":"2008","unstructured":"Coomer\n              AR\n            , LiptakJM. Canine histiocytic diseases. Compend Contin Educ Vet2008;30(4):202\u20134, 208\u201316 [quiz 216\u20137]."},{"issue":"4","key":"bib8","series-title":"Vet Clin North Am Small Anim Pract","first-page":"731","article-title":"Otitis externa. A disease of multifactorial etiology","volume":"18","author":"August","year":"1988","unstructured":"August\n              JR\n            \n          . Otitis externa. A disease of multifactorial etiology. Vet Clin North Am Small Anim Pract1988;18(4):731\u201342."},{"issue":"2","key":"bib9","series-title":"J Am Vet Med Assoc","first-page":"197","article-title":"Sebaceous adenitis in dogs and results of treatment with isotretinoin and etretinate: 30 cases (1990\u20131994)","volume":"207","author":"White","year":"1995","unstructured":"White\n              SD\n            , RosychukRA, ScottKV. Sebaceous adenitis in dogs and results of treatment with isotretinoin and etretinate: 30 cases (1990\u20131994). 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