{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:57:34Z","timestamp":1784134654835,"version":"3.55.0"},"reference-count":26,"publisher":"American Animal Hospital Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012]]},"abstract":"\n The role of\n Corynebacterium<\/jats:italic>\n spp. in the pathogenesis of canine and feline otitis externa\/media and their appropriate antimicrobial therapy are unclear. The objectives of this study were to (1) better establish the pathogenicity of\n Corynebacterium<\/jats:italic>\n spp. in otitis utilizing reported criteria and by assessing clinical response to antibiotic therapy and (2) to determine the antimicrobial susceptibility patterns of\n Corynebacterium<\/jats:italic>\n spp. associated with otitis. The study was retrospective, targeting cultures positive for\n Corynebacterium<\/jats:italic>\n spp.\n Corynebacterium<\/jats:italic>\n spp\n .<\/jats:italic>\n were part of mixed microbial populations in 79\/81 cultures.\n Corynebacterium<\/jats:italic>\n spp. pathogenicity was highly questionable because of their almost invariable presence with other microbes and the observation that\n Corynebacterium<\/jats:italic>\n spp. usually disappear from the ear with resolution of other infections, even when the\n Corynebacterium<\/jats:italic>\n spp. are resistant to the prescribed antibiotic(s). However, 2\/81 cultures came from two canine ears wherein\n Corynebacterium<\/jats:italic>\n spp. may have been pathogenic. Antimicrobial sensitivities for\n Corynebacterium<\/jats:italic>\n spp. were available for 54 isolates. Most isolates were susceptible to chloramphenicol (53\/54), amikacin (50\/54), tetracycline (50\/54), gentamicin (46\/54), and enrofloxacin (32\/54). Among those antibiotics available in otic products, gentamicin and enrofloxacin would be rational choices for the empirical, topical therapy of\n Corynebacterium<\/jats:italic>\n spp.\n <\/jats:p>","DOI":"10.5326\/jaaha-ms-5791","type":"journal-article","created":{"date-parts":[[2012,7,28]],"date-time":"2012-07-28T20:52:47Z","timestamp":1343508767000},"page":"320-326","source":"Crossref","is-referenced-by-count":26,"title":["Corynebacterium spp. in Dogs and Cats with Otitis Externa and\/or Media: A Retrospective Study"],"prefix":"10.5326","volume":"48","author":[{"given":"Kerstin","family":"Henneveld","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney A.W.","family":"Rosychuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Olea-Popelka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreene R.","family":"Hyatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Zabel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"1","key":"bib1","series-title":"Clin Microbiol Rev","first-page":"125","article-title":"Clinical microbiology of coryneform bacteria","volume":"10","author":"Funke","year":"1997","unstructured":"Funke\n G\n , von GraevenitzA, ClarridgeJEIII. 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