{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:56:24Z","timestamp":1783742184445,"version":"3.55.0"},"reference-count":17,"publisher":"American Animal Hospital Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>This retrospective study describes a technique and evaluates outcome associated with laparoscopic splenic biopsy in dogs and cats. Medical records of dogs (n = 10) and cats (n = 5) that had a laparoscopic splenic biopsy performed as part of their diagnostic evaluation for systemic disease were evaluated. Splenic biopsies were performed with the patient in dorsal recumbency using a two-portal approach. In some cases, concurrent organ biopsy was also performed. A pair of 5 mm cup biopsy forceps was used for biopsy collection, and an absorbable gelatin hemostatic sponge was placed at the biopsy site to aid in hemostasis. All patients recovered without major complications. Conversion to an open surgical approach was not required. Median survival time was 180 days, and nine patients were alive at the time of manuscript preparation. Four patients were diagnosed with neoplasia; however, only one had neoplasia involving the spleen. Median survival time for the nonneoplasia group (n = 11) was 300 days. Eight of those patients were alive at time of manuscript preparation. Minimal morbidity was observed in this cohort of clinical patients. Histopathology may be preferred over cytology in some clinical situations, and laparoscopic splenic biopsy provides a minimally invasive diagnostic option.<\/jats:p>","DOI":"10.5326\/jaaha-ms-5823","type":"journal-article","created":{"date-parts":[[2012,11,13]],"date-time":"2012-11-13T07:27:21Z","timestamp":1352791641000},"page":"41-45","source":"Crossref","is-referenced-by-count":14,"title":["Laparoscopic Splenic Biopsy in Dogs and Cats: 15 Cases (2006\u20132008)"],"prefix":"10.5326","volume":"49","author":[{"given":"Anant","family":"Radhakrishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp D.","family":"Mayhew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"3","key":"bib1","series-title":"Vet Surg","first-page":"243","article-title":"Comparison of biopsy samples obtained using standard endoscopic instruments and the harmonic scalpel during laparoscopic and laparoscopic-assisted surgery in normal dogs","volume":"35","author":"Barnes","year":"2006","unstructured":"Barnes\n              RF\n            , GreenfieldCL, SchaefferDJ. Comparison of biopsy samples obtained using standard endoscopic instruments and the harmonic scalpel during laparoscopic and laparoscopic-assisted surgery in normal dogs. Vet Surg2006;35(3):243\u201351."},{"issue":"1","key":"bib2","series-title":"Vet Surg","first-page":"86","article-title":"Evaluation of hemorrhage, sample size, and collateral damage for five hepatic biopsy methods in dogs","volume":"35","author":"Vasanjee","year":"2006","unstructured":"Vasanjee\n              SC\n            , BubenikLJ, HosgoodG. Evaluation of hemorrhage, sample size, and collateral damage for five hepatic biopsy methods in dogs. Vet Surg2006;35(1):86\u201393."},{"issue":"5","key":"bib3","series-title":"J Am Anim Hosp Assoc","first-page":"352","article-title":"Obtaining quality biopsies of the liver and kidney","volume":"40","author":"Rawlings","year":"2004","unstructured":"Rawlings\n              CA\n            , HowerthEW. Obtaining quality biopsies of the liver and kidney. J Am Anim Hosp Assoc2004;40(5):352\u20138."},{"issue":"9","key":"bib4","series-title":"Am J Vet Res","first-page":"1313","article-title":"Laparoscopic-assisted enterostomy tube placement and full-thickness biopsy of the jejunum with serosal patching in dogs","volume":"63","author":"Rawlings","year":"2002","unstructured":"Rawlings\n              CA\n            , HowerthEW, BementS. Laparoscopic-assisted enterostomy tube placement and full-thickness biopsy of the jejunum with serosal patching in dogs. Am J Vet Res2002;63(9):1313\u20139."},{"issue":"3","key":"bib5","series-title":"J Am Vet Med Assoc","first-page":"317","article-title":"Diagnostic quality of percutaneous kidney biopsy specimens obtained with laparoscopy versus ultrasound guidance in dogs","volume":"223","author":"Rawlings","year":"2003","unstructured":"Rawlings\n              CA\n            , DiamondH, HowerthEW. 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J Am Vet Med Assoc2007;230(5):690\u20136."},{"issue":"1","key":"bib7","series-title":"J Am Vet Med Assoc","first-page":"75","article-title":"Accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990\u20132000)","volume":"224","author":"Wang","year":"2004","unstructured":"Wang\n              KY\n            , PancieraDL, Al-RukibatRK. Accuracy of ultrasound-guided fine-needle aspiration of the liver and cytologic findings in dogs and cats: 97 cases (1990\u20132000). J Am Vet Med Assoc2004;224(1):75\u20138."},{"issue":"10","key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"1483","article-title":"Diagnostic comparison of needle and wedge biopsy specimens of the liver in dogs and cats","volume":"220","author":"Cole","year":"2002","unstructured":"Cole\n              TL\n            , CenterSA, FloodSN. Diagnostic comparison of needle and wedge biopsy specimens of the liver in dogs and cats. J Am Vet Med Assoc2002;220(10):1483\u201390."},{"issue":"4","key":"bib9","series-title":"AJR Am J Roentgenol","first-page":"1025","article-title":"Imaging-guided percutaneous splenic biopsy using a 20- or 22-gauge cutting-edge core biopsy needle for the diagnosis of malignant lymphoma","volume":"181","author":"Lieberman","year":"2003","unstructured":"Lieberman\n              S\n            , LibsonE, MalyB. Imaging-guided percutaneous splenic biopsy using a 20- or 22-gauge cutting-edge core biopsy needle for the diagnosis of malignant lymphoma. AJR Am J Roentgenol2003;181(4):1025\u20137."},{"issue":"6","key":"bib10","series-title":"AJR Am J Roentgenol","first-page":"1591","article-title":"Percutaneous nonvascular splenic intervention: a 10-year review","volume":"179","author":"Lucey","year":"2002","unstructured":"Lucey\n              BC\n            , BolandGW, MaherMM. Percutaneous nonvascular splenic intervention: a 10-year review. AJR Am J Roentgenol2002;179(6):1591\u20136."},{"issue":"4","key":"bib11","series-title":"AJR Am J Roentgenol","first-page":"933","article-title":"Imaging-guided percutaneous biopsy of focal splenic lesions: update on safety and effectiveness","volume":"172","author":"Keogan","year":"1999","unstructured":"Keogan\n              MT\n            , FreedKS, PaulsonEK. Imaging-guided percutaneous biopsy of focal splenic lesions: update on safety and effectiveness. AJR Am J Roentgenol1999;172(4):933\u20137."},{"issue":"12","key":"bib12","series-title":"Cancer","first-page":"2932","article-title":"Ultrasonically guided percutaneous splenic tissue core biopsy in patients with malignant lymphomas","volume":"69","author":"Cavanna","year":"1992","unstructured":"Cavanna\n              L\n            , CivardiG, FornariF. Ultrasonically guided percutaneous splenic tissue core biopsy in patients with malignant lymphomas. 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Compend Contin Educ Pract Vet2005;27:17\u201332."},{"issue":"1","key":"bib17","series-title":"Vet Immunol Immunopathol","first-page":"15","article-title":"Investigation of splenic functions in canine monocytic ehrlichiosis","volume":"62","author":"Harrus","year":"1998","unstructured":"Harrus\n              S\n            , WanerT, KeysaryA. Investigation of splenic functions in canine monocytic ehrlichiosis. Vet Immunol Immunopathol1998;62(1):15\u201327."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/49\/1\/article-p41.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/49\/1\/41\/1335114\/jaaha-ms-5823.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/49\/1\/article-p41.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/49\/1\/article-p41.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T15:58:15Z","timestamp":1763740695000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/49\/1\/article-p41.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":17,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-5823","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}