{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:32:15Z","timestamp":1778279535708,"version":"3.51.4"},"reference-count":12,"publisher":"American Animal Hospital Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"abstract":"Pyrethroids are popular for use in companion animals due to their relatively low mammalian toxicity and efficacy against arthropods. Nonetheless, pyrethroid intoxication has been reported in cats and dogs, and cats appear to be more susceptible due to difficulty in biotransformation and excretion of pyrethroids. Pyrethroid intoxications are generally due to either the improper use or accidental ingestion of approved products. Methocarbamol, given as intermittent injections, is a common first-line treatment choice for the tremors associated with pyrethroid intoxication. Two cats and one dog were treated with a methocarbamol continuous rate infusion (CRI) for pyrethroid intoxication. Clinical signs of toxicity resolved within a few hr in all three cases, with no adverse drug effects. A methocarbamol CRI can be considered in animals presenting with pyrethroid intoxication.<\/jats:p>","DOI":"10.5326\/jaaha-ms-5835","type":"journal-article","created":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T21:56:58Z","timestamp":1364421418000},"page":"325-328","source":"Crossref","is-referenced-by-count":3,"title":["Methocarbamol CRI for Symptomatic Treatment of Pyrethroid Intoxication: A Report of Three Cases"],"prefix":"10.5326","volume":"49","author":[{"given":"William E.","family":"Draper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz","family":"Bolfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Cottam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"McMichael","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Schubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"J Vet Emerg Crit Care","first-page":"103","article-title":"Permethrin spot-on toxicosis in cats","volume":"10","author":"Richardson","year":"2000","unstructured":"Richardson\n JA\n \n . 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The national veterinary medical series. Hoboken (NJ): John Wiley & Sons; 1996: 241\u20133."},{"key":"bib5","series-title":"Comp Cont Educ Pract Vet","first-page":"707","article-title":"Pyrethrins and pyrethroids in dogs and cats","volume":"16","author":"Hansen","year":"1994","unstructured":"Hansen\n SR\n , StemmeK, VillarD. Pyrethrins and pyrethroids in dogs and cats. Comp Cont Educ Pract Vet1994;16:707\u201312."},{"issue":"6","key":"bib6","series-title":"Aust Vet J","first-page":"219","article-title":"Permethrin toxicity in cats: a retrospective study of 20 cases","volume":"86","author":"Dymond","year":"2008","unstructured":"Dymond\n NL\n , SwiftIM. Permethrin toxicity in cats: a retrospective study of 20 cases. Aust Vet J2008;86(6):219\u201323."},{"issue":"2","key":"bib7","series-title":"J Feline Med Surg","first-page":"61","article-title":"Feline permethrin toxicity: retrospective study of 42 cases","volume":"12","author":"Boland","year":"2010","unstructured":"Boland\n LA\n , AnglesJM. Feline permethrin toxicity: retrospective study of 42 cases. J Feline Med Surg2010;12(2):61\u201371."},{"issue":"19","key":"bib8","series-title":"Vet Rec","first-page":"556","article-title":"Permethrin toxicity in cats","volume":"147","author":"Gray","year":"2000","unstructured":"Gray\n A\n \n . Permethrin toxicity in cats. Vet Rec2000;147(19):556."},{"issue":"2","key":"bib9","series-title":"J Am Vet Med Assoc","first-page":"198","article-title":"Toxicosis in cats erroneously treated with 45 to 65% permethrin products","volume":"215","author":"Meyer","year":"1999","unstructured":"Meyer\n EK\n \n . Toxicosis in cats erroneously treated with 45 to 65% permethrin products. J Am Vet Med Assoc1999;215(2):198\u2013203."},{"issue":"6","key":"bib10","series-title":"J Am Vet Med Assoc","first-page":"800","article-title":"Warning against use of some permethrin products in cats","volume":"213","author":"Volmer","year":"1998","unstructured":"Volmer\n PA\n , KahnSA, KnightMW. Warning against use of some permethrin products in cats. J Am Vet Med Assoc1998;213(6):800\u20131."},{"key":"bib11","series-title":"J Pharmacol Exp Ther","first-page":"75","article-title":"A pharmacological comparison of therapeutically useful centrally acting skeletal muscle relaxants","volume":"129","author":"Roszkowski","year":"1960","unstructured":"Roszkowski\n AP\n \n . A pharmacological comparison of therapeutically useful centrally acting skeletal muscle relaxants. 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