{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T03:08:25Z","timestamp":1774494505315,"version":"3.50.1"},"reference-count":20,"publisher":"American Animal Hospital Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>A 4 yr old castrated male Jack Russell terrier was presented with a 2 mo history of vomiting, anorexia, and weight loss. Abdominal radiographs and ultrasound supported the diagnosis of gastric outflow obstruction. Celiotomy and gastrotomy revealed a large, narrowly based mass originating from the mucosa of the dorsal gastric body, occupying the lumen of the stomach and protruding through the pylorus into the duodenum. A partial gastrectomy was performed to excise the mass along with a 1 cm margin of grossly normal tissue. Giant hypertrophic gastritis was diagnosed via histopathology of the excised tissue. Giant hypertrophic gastritis is a rarely diagnosed disease of canines, characterized by giant gastric folds, hypoalbuminemia, and mucosal hypertrophy. Long-term treatment success has not been previously reported. In the case described herein, surgical excision of the affected gastric tissue provided complete resolution of clinical signs. Twelve mo following surgery, no recurrence of either vomiting or weight loss had been noted and the dog was clinically normal.<\/jats:p>","DOI":"10.5326\/jaaha-ms-5952","type":"journal-article","created":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T23:28:20Z","timestamp":1384212500000},"page":"62-66","source":"Crossref","is-referenced-by-count":11,"title":["Canine Giant Hypertrophic Gastritis Treated Successfully with Partial Gastrectomy"],"prefix":"10.5326","volume":"50","author":[{"given":"Denty P.","family":"Vaughn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Syrcle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim","family":"Cooley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"issue":"2","key":"bib1","series-title":"J Am Anim Hosp Assoc","first-page":"122","article-title":"Giant hypertrophic gastritis (Menetrier\u2019s-like disease) in an Old English sheepdog","volume":"43","author":"Rallis","year":"2007","unstructured":"Rallis\n              TS\n            , PatsikasMN, MylonakisME. Giant hypertrophic gastritis (Menetrier\u2019s-like disease) in an Old English sheepdog. J Am Anim Hosp Assoc2007;43(2):122\u20137."},{"issue":"2","key":"bib2","series-title":"J Am Vet Med Assoc","first-page":"182","article-title":"Focal cystic hypertrophic gastropathy in a dog","volume":"173","author":"Kipnis","year":"1978","unstructured":"Kipnis\n              RM\n            \n          . Focal cystic hypertrophic gastropathy in a dog. J Am Vet Med Assoc1978;173(2):182\u20134."},{"issue":"3","key":"bib3","series-title":"Vet Pathol","first-page":"172","article-title":"A boxer dog with chronic hypertrophic gastritis resembling Menetrier\u2019s disease in man","volume":"13","author":"van der Gaag","year":"1976","unstructured":"van der Gaag\n              I\n            , Happ\u00e9RP, WolvekampWT. A boxer dog with chronic hypertrophic gastritis resembling Menetrier\u2019s disease in man. Vet Pathol1976;13(3):172\u201385."},{"issue":"1","key":"bib4","series-title":"Vet Pathol","first-page":"19","article-title":"Giant hypertrophic gastritis of Basenji dogs","volume":"14","author":"Krunngen","year":"1977","unstructured":"Krunngen\n              HJ\n            \n          . Giant hypertrophic gastritis of Basenji dogs. Vet Pathol1977;14(1):19\u201328."},{"issue":"1","key":"bib5","series-title":"Vet Q","first-page":"30","article-title":"Familial stomatocytosis\u2014hypertrophic gastritis (FSHG), a newly recognised disease in the dog (Drentse patrijshond)","volume":"13","author":"Slappendel","year":"1991","unstructured":"Slappendel\n              RJ\n            , van der GaagI, van NesJJ. Familial stomatocytosis\u2014hypertrophic gastritis (FSHG), a newly recognised disease in the dog (Drentse patrijshond). 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Vet Ther2008;9(2):83\u201393."},{"issue":"3","key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"318","article-title":"Efficacy of oral transmucosal and intravenous administration of buprenorphine before surgery for postoperative analgesia in dogs undergoing ovariohysterectomy","volume":"238","author":"Ko","year":"2011","unstructured":"Ko\n              JC\n            , FreemanLJ, BarlettaM. Efficacy of oral transmucosal and intravenous administration of buprenorphine before surgery for postoperative analgesia in dogs undergoing ovariohysterectomy. J Am Vet Med Assoc2011;238(3):318\u201328."},{"issue":"1","key":"bib9","series-title":"J Clin Invest","first-page":"70","article-title":"M\u00e9n\u00e9trier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach","volume":"117","author":"Coffey","year":"2007","unstructured":"Coffey\n              RJ\n            , WashingtonMK, CorlessCL. M\u00e9n\u00e9trier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach. J Clin Invest2007;117(1):70\u201380."},{"issue":"8","key":"bib10","series-title":"Sci Transl Med","first-page":"8","article-title":"Efficacy of cetuximab in the treatment of Menetrier\u2019s disease","volume":"1","author":"Fiske","year":"2009","unstructured":"Fiske\n              WH\n            , TanksleyJ, NamKT. Efficacy of cetuximab in the treatment of Menetrier\u2019s disease. Sci Transl Med2009;1(8):8ra18."},{"issue":"2","key":"bib1","series-title":"J Am Anim Hosp Assoc","first-page":"122","article-title":"Giant hypertrophic gastritis (Menetrier\u2019s-like disease) in an Old English sheepdog","volume":"43","author":"Rallis","year":"2007","unstructured":"Rallis\n              TS\n            , PatsikasMN, MylonakisME. Giant hypertrophic gastritis (Menetrier\u2019s-like disease) in an Old English sheepdog. J Am Anim Hosp Assoc2007;43(2):122\u20137."},{"issue":"2","key":"bib2","series-title":"J Am Vet Med Assoc","first-page":"182","article-title":"Focal cystic hypertrophic gastropathy in a dog","volume":"173","author":"Kipnis","year":"1978","unstructured":"Kipnis\n              RM\n            \n          . Focal cystic hypertrophic gastropathy in a dog. J Am Vet Med Assoc1978;173(2):182\u20134."},{"issue":"3","key":"bib3","series-title":"Vet Pathol","first-page":"172","article-title":"A boxer dog with chronic hypertrophic gastritis resembling Menetrier\u2019s disease in man","volume":"13","author":"van der Gaag","year":"1976","unstructured":"van der Gaag\n              I\n            , Happ\u00e9RP, WolvekampWT. A boxer dog with chronic hypertrophic gastritis resembling Menetrier\u2019s disease in man. 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Vet Ther2008;9(2):83\u201393."},{"issue":"3","key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"318","article-title":"Efficacy of oral transmucosal and intravenous administration of buprenorphine before surgery for postoperative analgesia in dogs undergoing ovariohysterectomy","volume":"238","author":"Ko","year":"2011","unstructured":"Ko\n              JC\n            , FreemanLJ, BarlettaM. Efficacy of oral transmucosal and intravenous administration of buprenorphine before surgery for postoperative analgesia in dogs undergoing ovariohysterectomy. J Am Vet Med Assoc2011;238(3):318\u201328."},{"issue":"1","key":"bib9","series-title":"J Clin Invest","first-page":"70","article-title":"M\u00e9n\u00e9trier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach","volume":"117","author":"Coffey","year":"2007","unstructured":"Coffey\n              RJ\n            , WashingtonMK, CorlessCL. 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