{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:15:23Z","timestamp":1763741723144,"version":"3.45.0"},"reference-count":22,"publisher":"American Animal Hospital Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:title\/>\n                  <jats:p>\n                    A 12 yr old female neutered Carthusian crossbreed cat was presented due to progressive neurological signs. Clinical signs included dehydration, stupor, and anisocoria. Laboratory examination revealed severe hypernatremia, azotemia, hyperglobulinemia, and an erythrocytosis. Clinical signs and hypernatremia suggested an intracranial process. Imaging studies revealed a loss of structure in the cerebrum, hypothalamus, and pituitary gland. Due to a poor prognosis, the cat was euthanatized. Histopathological examination revealed a subacute granulomatous and necrotizing panencephalitis with\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    -typical protozoa. The\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    -induced dysfunction of the hypothalamus and pituitary gland led to diabetes insipidus, which was, in combination with insufficient water intake, the most likely cause for the hypernatremia.\n                  <\/jats:p>","DOI":"10.5326\/jaaha-ms-6257","type":"journal-article","created":{"date-parts":[[2015,11,25]],"date-time":"2015-11-25T15:47:56Z","timestamp":1448466476000},"page":"63-67","source":"Crossref","is-referenced-by-count":3,"title":["Hypernatremia in a Cat with Toxoplasma-Induced Panencephalitis"],"prefix":"10.5326","volume":"52","author":[{"given":"Christiane","family":"Weingart","sequence":"first","affiliation":[{"name":"From the Department of Veterinary Pathology (A.D.G.) and Clinic of Small Animals (C.W., M.B., B.K.), Freie Universit\u00e4t Berlin, Berlin, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Achim D.","family":"Gruber","sequence":"additional","affiliation":[{"name":"From the Department of Veterinary Pathology (A.D.G.) and Clinic of Small Animals (C.W., M.B., B.K.), Freie Universit\u00e4t Berlin, Berlin, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathias","family":"Brunnberg","sequence":"additional","affiliation":[{"name":"From the Department of Veterinary Pathology (A.D.G.) and Clinic of Small Animals (C.W., M.B., B.K.), Freie Universit\u00e4t Berlin, Berlin, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Kohn","sequence":"additional","affiliation":[{"name":"From the Department of Veterinary Pathology (A.D.G.) and Clinic of Small Animals (C.W., M.B., B.K.), Freie Universit\u00e4t Berlin, Berlin, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"i1547-3317-52-1-63-b01","series-title":"Fluid, electrolyte and acid-base disorders in small animal practice. 4th ed","first-page":"45","article-title":"Disorders of sodium and water: hypernatremia and hyponatremia","author":"DiBartola\n              S.","year":"2012","unstructured":"DiBartola\n              S.\n            \n          \n          Disorders of sodium and water: hypernatremia and hyponatremia. 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