{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T00:28:25Z","timestamp":1782520105194,"version":"3.54.5"},"reference-count":30,"publisher":"American Animal Hospital Association","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 5 yr old castrated male whippet presented with a unique presentation of ambulatory paraparesis and subsequent diagnosis of primary intracranial choroid plexus carcinoma, with metastases to the cervical, thoracic, lumbar, and sacral spinal cord segments. Magnetic resonance imaging was performed initially of the thoracolumbar vertebral column and was followed by MRI sequences of the brain for confirmation of the presence of a primary intracranial tumor. The dog was euthanized immediately following diagnostic imaging due to the severity of clinical signs and poor prognosis. Postmortem examination confirmed the presence of a primary choroid plexus carcinoma, with diffuse metastatic lesions to the spinal cord. To the authors\u2019 knowledge, this is the first description of MRI findings of spinal cord metastasis of a choroid plexus carcinoma in a dog. Additionally, this case demonstrates primary clinical signs arising from metastatic lesions. This confirms the importance of extensive neuroimaging investigations when suspecting choroid plexus tumors and evaluating response to treatment regimens.<\/jats:p>","DOI":"10.5326\/jaaha-ms-6479","type":"journal-article","created":{"date-parts":[[2017,8,9]],"date-time":"2017-08-09T16:58:55Z","timestamp":1502297935000},"page":"265-269","source":"Crossref","is-referenced-by-count":8,"title":["Magnetic Resonance Imaging and Clinical Findings Associated with Choroid Plexus Spinal Cord \u201cDrop\u201d Metastases"],"prefix":"10.5326","volume":"53","author":[{"given":"Carmen L.","family":"Yeamans","sequence":"first","affiliation":[{"name":"From the University of Glasgow, Glasgow, United Kingdom (C.L.Y., R.G-Q.); Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia (A.H.); and Idexx Labratories, Sacramento, California (C.G.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Gutierrez-Quintana","sequence":"additional","affiliation":[{"name":"From the University of Glasgow, Glasgow, United Kingdom (C.L.Y., R.G-Q.); Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia (A.H.); and Idexx Labratories, Sacramento, California (C.G.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Haley","sequence":"additional","affiliation":[{"name":"From the University of Glasgow, Glasgow, United Kingdom (C.L.Y., R.G-Q.); Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia (A.H.); and Idexx Labratories, Sacramento, California (C.G.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine G.","family":"Lamm","sequence":"additional","affiliation":[{"name":"From the University of Glasgow, Glasgow, United Kingdom (C.L.Y., R.G-Q.); Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia (A.H.); and Idexx Labratories, Sacramento, California (C.G.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"J Vet Intern Med","first-page":"1143","article-title":"Postmortem Evaluation of 435 Cases of Intracranial Neoplasia in Dogs and Relationship of Neoplasm with Breed, Age, and Body Weight","volume":"27","author":"Song\n              RB","year":"2013","unstructured":"Song\n              RB\n            , ViteCH, BradleyCW, et al. Postmortem Evaluation of 435 Cases of Intracranial Neoplasia in Dogs and Relationship of Neoplasm with Breed, Age, and Body Weight. J Vet Intern Med2013;27:1143\u201352."},{"issue":"20","key":"bib2","series-title":"J Vet Intern Med","first-page":"669","article-title":"Canine Intracranial Primary Neoplasia: 173 cases (1986\u20132003)","volume":"2006","author":"Snyder\n              JM","unstructured":"Snyder\n              JM\n            , ShoferFS, Van WinkleTJ, et al. Canine Intracranial Primary Neoplasia: 173 cases (1986\u20132003). J Vet Intern Med2006;20:669\u201375."},{"issue":"22","key":"bib3","series-title":"J Vet Intern Med","first-page":"1157","article-title":"Choroid Plexus Tumors in 56 Dogs","volume":"2008","author":"Westworth\n              DR","year":"1985\u20132007","unstructured":"Westworth\n              DR\n            , DickinsonPJ, VernauW, et al. Choroid Plexus Tumors in 56 Dogs (1985\u20132007). J Vet Intern Med2008;22:1157\u201365."},{"key":"bib4","series-title":"Vet Pathol","first-page":"55","article-title":"A Histologic and Immunocytochemical Study of Choroid Plexus Tumors of the Dog","volume":"26","author":"Ribas\n              JL","year":"1989","unstructured":"Ribas\n              JL\n            , MenaH, BraundKG, et al. A Histologic and Immunocytochemical Study of Choroid Plexus Tumors of the Dog. Vet Pathol1989;26:55\u201364."},{"key":"bib5","series-title":"J Comp Path","first-page":"183","article-title":"Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog","volume":"126","author":"Cantile\n              C","year":"2002","unstructured":"Cantile\n              C\n            , CampanibD, MenicagliM, et al. Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog. J Comp Path2002;126:183\u201393."},{"key":"bib6","series-title":"Vet Radiol Ultrasound","first-page":"s52","article-title":"Magnetic resonance imaging features of canine intracranial neoplasia","volume":"52","author":"Wisner\n              ER","year":"2011","unstructured":"Wisner\n              ER\n            , DickinsonPJ, HigginsRJ. Magnetic resonance imaging features of canine intracranial neoplasia. Vet Radiol Ultrasound2011;52:s52\u2013s61."},{"key":"bib7","series-title":"Clin Neuro Neurosur","first-page":"165","article-title":"Pathology of choroid plexus papillomas: A review","volume":"100","author":"Gaudio\n              RM","year":"1998","unstructured":"Gaudio\n              RM\n            , TacconiL, RossiMLM. Pathology of choroid plexus papillomas: A review. Clin Neuro Neurosur1998;100:165\u201386."},{"key":"bib8","series-title":"Am J Surg Pathol","first-page":"394","article-title":"Choroid Plexus Neoplasms: Clinicopathologic and immunohistochemical studies","volume":"10","author":"Coffin\n              CM","year":"1986","unstructured":"Coffin\n              CM\n            , WickMR, BraunJT, et al. Choroid Plexus Neoplasms: Clinicopathologic and immunohistochemical studies. Am J Surg Pathol1986;10:394\u201304"},{"key":"bib9","series-title":"Br J Cancer","first-page":"1086","article-title":"Choroid Plexus Tumors","volume":"87","author":"Wolf\n              JEA","year":"2002","unstructured":"Wolf\n              JEA\n            , SajediM, BrantR, et al. Choroid Plexus Tumors. Br J Cancer. 2002;87:1086\u201391."},{"key":"bib10","series-title":"J Neurosurg","first-page":"251","article-title":"Malignant choroid plexus papilloma with extraneural metastasis","volume":"52","author":"Valladeres\n              JB","year":"1980","unstructured":"Valladeres\n              JB\n            , PerryRH, KalbagRM. Malignant choroid plexus papilloma with extraneural metastasis. J Neurosurg1980;52:251\u20135."},{"key":"bib11","series-title":"Acta Psychiatr Neurol","first-page":"299","article-title":"Papilloma of the choroid plexus with pulmonary metastasis","volume":"25","author":"Vraa-Jensen\n              G","year":"1950","unstructured":"Vraa-Jensen\n              G\n            \n          . Papilloma of the choroid plexus with pulmonary metastasis. Acta Psychiatr Neurol1950;25:299\u2013306."},{"key":"bib12","series-title":"J Neurosurg","first-page":"757","article-title":"Diffuse craniospinal seeding from benign fourth ventricle choroid plexus papilloma","volume":"88","author":"Leblanc\n              R","year":"1998","unstructured":"Leblanc\n              R\n            , BekhorS, MelansonD, et al. Diffuse craniospinal seeding from benign fourth ventricle choroid plexus papilloma. J Neurosurg. 1998;88:757\u201360."},{"key":"bib13","series-title":"Case Reports in Veterinary Medicine","article-title":"Canine choroid plexus tumor with intracranial dissemination presenting as multiple cystic lesions","author":"Oura\n              TJ","year":"2013","unstructured":"Oura\n              TJ\n            , EarlyPJ, JenningsSH, et al. Canine choroid plexus tumor with intracranial dissemination presenting as multiple cystic lesions. Case Reports in Veterinary Medicine2013. Available at: http:\/\/dx.doi.org\/10.1155\/2013\/759054."},{"key":"bib14","series-title":"J Neurooncol","first-page":"75","article-title":"Choroid plexus carcinoma presented with spinal dysfunction caused by drop metastasis: a case report","volume":"63","author":"Sawaishi\n              Y","year":"2003","unstructured":"Sawaishi\n              Y\n            , YanoT, YoshidaY, et al. Choroid plexus carcinoma presented with spinal dysfunction caused by drop metastasis: a case report. J Neurooncol2003;63:75\u20139"},{"key":"bib15","series-title":"Vet Pathol","first-page":"381","article-title":"Choroid plexus carcinoma with meningeal carcinomatosis in a dog","volume":"17","author":"Patnaik\n              AK","year":"1980","unstructured":"Patnaik\n              AK\n            , ErlandsonRA, LiebermanPH, et al. Choroid plexus carcinoma with meningeal carcinomatosis in a dog. Vet Pathol1980;17:381\u20135."},{"key":"bib1","series-title":"J Vet Intern Med","first-page":"1143","article-title":"Postmortem Evaluation of 435 Cases of Intracranial Neoplasia in Dogs and Relationship of Neoplasm with Breed, Age, and Body Weight","volume":"27","author":"Song\n              RB","year":"2013","unstructured":"Song\n              RB\n            , ViteCH, BradleyCW, et al. Postmortem Evaluation of 435 Cases of Intracranial Neoplasia in Dogs and Relationship of Neoplasm with Breed, Age, and Body Weight. J Vet Intern Med2013;27:1143\u201352."},{"issue":"20","key":"bib2","series-title":"J Vet Intern Med","first-page":"669","article-title":"Canine Intracranial Primary Neoplasia: 173 cases (1986\u20132003)","volume":"2006","author":"Snyder\n              JM","unstructured":"Snyder\n              JM\n            , ShoferFS, Van WinkleTJ, et al. Canine Intracranial Primary Neoplasia: 173 cases (1986\u20132003). J Vet Intern Med2006;20:669\u201375."},{"issue":"22","key":"bib3","series-title":"J Vet Intern Med","first-page":"1157","article-title":"Choroid Plexus Tumors in 56 Dogs","volume":"2008","author":"Westworth\n              DR","year":"1985\u20132007","unstructured":"Westworth\n              DR\n            , DickinsonPJ, VernauW, et al. Choroid Plexus Tumors in 56 Dogs (1985\u20132007). J Vet Intern Med2008;22:1157\u201365."},{"key":"bib4","series-title":"Vet Pathol","first-page":"55","article-title":"A Histologic and Immunocytochemical Study of Choroid Plexus Tumors of the Dog","volume":"26","author":"Ribas\n              JL","year":"1989","unstructured":"Ribas\n              JL\n            , MenaH, BraundKG, et al. A Histologic and Immunocytochemical Study of Choroid Plexus Tumors of the Dog. Vet Pathol1989;26:55\u201364."},{"key":"bib5","series-title":"J Comp Path","first-page":"183","article-title":"Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog","volume":"126","author":"Cantile\n              C","year":"2002","unstructured":"Cantile\n              C\n            , CampanibD, MenicagliM, et al. Pathological and immunohistochemical studies of choroid plexus carcinoma of the dog. J Comp Path2002;126:183\u201393."},{"key":"bib6","series-title":"Vet Radiol Ultrasound","first-page":"s52","article-title":"Magnetic resonance imaging features of canine intracranial neoplasia","volume":"52","author":"Wisner\n              ER","year":"2011","unstructured":"Wisner\n              ER\n            , DickinsonPJ, HigginsRJ. Magnetic resonance imaging features of canine intracranial neoplasia. Vet Radiol Ultrasound2011;52:s52\u2013s61."},{"key":"bib7","series-title":"Clin Neuro Neurosur","first-page":"165","article-title":"Pathology of choroid plexus papillomas: A review","volume":"100","author":"Gaudio\n              RM","year":"1998","unstructured":"Gaudio\n              RM\n            , TacconiL, RossiMLM. Pathology of choroid plexus papillomas: A review. Clin Neuro Neurosur1998;100:165\u201386."},{"key":"bib8","series-title":"Am J Surg Pathol","first-page":"394","article-title":"Choroid Plexus Neoplasms: Clinicopathologic and immunohistochemical studies","volume":"10","author":"Coffin\n              CM","year":"1986","unstructured":"Coffin\n              CM\n            , WickMR, BraunJT, et al. Choroid Plexus Neoplasms: Clinicopathologic and immunohistochemical studies. Am J Surg Pathol1986;10:394\u201304"},{"key":"bib9","series-title":"Br J Cancer","first-page":"1086","article-title":"Choroid Plexus Tumors","volume":"87","author":"Wolf\n              JEA","year":"2002","unstructured":"Wolf\n              JEA\n            , SajediM, BrantR, et al. Choroid Plexus Tumors. Br J Cancer. 2002;87:1086\u201391."},{"key":"bib10","series-title":"J Neurosurg","first-page":"251","article-title":"Malignant choroid plexus papilloma with extraneural metastasis","volume":"52","author":"Valladeres\n              JB","year":"1980","unstructured":"Valladeres\n              JB\n            , PerryRH, KalbagRM. Malignant choroid plexus papilloma with extraneural metastasis. J Neurosurg1980;52:251\u20135."},{"key":"bib11","series-title":"Acta Psychiatr Neurol","first-page":"299","article-title":"Papilloma of the choroid plexus with pulmonary metastasis","volume":"25","author":"Vraa-Jensen\n              G","year":"1950","unstructured":"Vraa-Jensen\n              G\n            \n          . Papilloma of the choroid plexus with pulmonary metastasis. Acta Psychiatr Neurol1950;25:299\u2013306."},{"key":"bib12","series-title":"J Neurosurg","first-page":"757","article-title":"Diffuse craniospinal seeding from benign fourth ventricle choroid plexus papilloma","volume":"88","author":"Leblanc\n              R","year":"1998","unstructured":"Leblanc\n              R\n            , BekhorS, MelansonD, et al. Diffuse craniospinal seeding from benign fourth ventricle choroid plexus papilloma. J Neurosurg. 1998;88:757\u201360."},{"key":"bib13","series-title":"Case Reports in Veterinary Medicine","article-title":"Canine choroid plexus tumor with intracranial dissemination presenting as multiple cystic lesions","author":"Oura\n              TJ","year":"2013","unstructured":"Oura\n              TJ\n            , EarlyPJ, JenningsSH, et al. Canine choroid plexus tumor with intracranial dissemination presenting as multiple cystic lesions. Case Reports in Veterinary Medicine2013. Available at: http:\/\/dx.doi.org\/10.1155\/2013\/759054."},{"key":"bib14","series-title":"J Neurooncol","first-page":"75","article-title":"Choroid plexus carcinoma presented with spinal dysfunction caused by drop metastasis: a case report","volume":"63","author":"Sawaishi\n              Y","year":"2003","unstructured":"Sawaishi\n              Y\n            , YanoT, YoshidaY, et al. Choroid plexus carcinoma presented with spinal dysfunction caused by drop metastasis: a case report. J Neurooncol2003;63:75\u20139"},{"key":"bib15","series-title":"Vet Pathol","first-page":"381","article-title":"Choroid plexus carcinoma with meningeal carcinomatosis in a dog","volume":"17","author":"Patnaik\n              AK","year":"1980","unstructured":"Patnaik\n              AK\n            , ErlandsonRA, LiebermanPH, et al. Choroid plexus carcinoma with meningeal carcinomatosis in a dog. Vet Pathol1980;17:381\u20135."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/53\/5\/article-p265.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/53\/5\/265\/1745516\/jaaha-ms-6479.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/53\/5\/article-p265.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/53\/5\/article-p265.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:31:18Z","timestamp":1772325078000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/53\/5\/article-p265.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":30,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-6479","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}