{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T16:08:52Z","timestamp":1785600532029,"version":"3.56.0"},"reference-count":24,"publisher":"American Animal Hospital Association","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Rhinoscopy was performed on 10 dogs with sinonasal aspergillosis (SNA). Direct access to the sinus via the nasal ostium was possible with a flexible endoscope to allow sinuscopy. Debridement of fungal plaques in the frontal sinus and the nasal cavity was performed, and a sinus and nasal deposition therapy with clotrimazole (1%) cream was made under rhinoscopic guidance. No oral medication was administered following the procedure. A rhinoscopic follow-up was performed monthly until cure. Six of ten (60%) dogs presented fungal plaques in the nasal cavity and in the frontal sinus and 4\/10 (40%) dogs presented fungal plaques only in the frontal sinus. Five of ten (50%) dogs were considered to be cured at the first follow-up rhinoscopy, 4\/10 (40%) after the second follow-up, and 1\/10 (10%) after the third. Two dogs had delayed recurrence of SNA rhinoscopically assessed 12 and 21 mo, respectively, after the last clotrimazole treatment. Endoscopic debridement of fungal plaques and clotrimazole (1%) cream deposition therapy seems to be a valuable minimally invasive technique for SNA treatment in dogs without the use of complementary oral medication. Delayed recurrence is a potential finding following treatment of SNA.<\/jats:p>","DOI":"10.5326\/jaaha-ms-6648","type":"journal-article","created":{"date-parts":[[2018,1,26]],"date-time":"2018-01-26T09:11:41Z","timestamp":1516957901000},"page":"103-110","source":"Crossref","is-referenced-by-count":8,"title":["Treatment of Sinonasal Aspergillosis by Debridement and Sinonasal Deposition Therapy with Clotrimazole Under Rhinoscopic Guidance"],"prefix":"10.5326","volume":"54","author":[{"given":"Bertrand","family":"Vedrine","sequence":"first","affiliation":[{"name":"From the Clinique V\u00e9t\u00e9rinaire Seinevet, 5 Place Cauchoise, 76000 Rouen, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc-Andr\u00e9","family":"Fribourg-Blanc","sequence":"additional","affiliation":[{"name":"From the Clinique V\u00e9t\u00e9rinaire Seinevet, 5 Place Cauchoise, 76000 Rouen, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3280","reference":[{"issue":"6","key":"bib1","series-title":"J Small Anim Pract","first-page":"312","article-title":"Combined clotrimazole irrigation and depot therapy for canine nasal aspergillosis","volume":"47","author":"Sissener\n              TR","year":"2006","unstructured":"Sissener\n              TR\n            , BaconNJ, FriendE, et al. 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