{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T15:40:35Z","timestamp":1772034035225,"version":"3.50.1"},"reference-count":25,"publisher":"American Animal Hospital Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Five dogs were presented with clinical signs compatible with upper airway obstruction, including stridor, stertor, coughing, gagging, and varying degrees of respiratory distress. All dogs had radiographic findings of soft tissue opacity in the area of the pharynx, larynx, or trachea, and several had narrowing of the tracheal lumen. Coagulation abnormalities (prolonged prothrombin time, activated partial thromboplastin time) were present in the four dogs that underwent testing. Four of five dogs were treated for the coagulopathy, presumably due to anticoagulant rodenticide toxicosis, and survived to discharge.Upper airway obstruction is an unusual presentation for anticoagulant rodenticide toxicosis in dogs. Raising the index of suspicion for this treatable condition may help clinicians to identify this sooner.<\/jats:p>","DOI":"10.5326\/jaaha-ms-6658","type":"journal-article","created":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T15:24:18Z","timestamp":1495553058000},"page":"236-241","source":"Crossref","is-referenced-by-count":5,"title":["Upper Airway Obstruction Secondary to Anticoagulant Rodenticide Toxicosis in Five Dogs"],"prefix":"10.5326","volume":"53","author":[{"given":"Corinne","family":"Lawson","sequence":"first","affiliation":[{"name":"From the University of Illinois, Urbana, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauria","family":"O'Brien","sequence":"additional","affiliation":[{"name":"From the University of Illinois, Urbana, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"McMichael","sequence":"additional","affiliation":[{"name":"From the University of Illinois, Urbana, Illinois."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"i1547-3317-53-4-236-b01","series-title":"Vet Med","first-page":"142","article-title":"The 10 Most Common Toxicoses in Dogs","author":"Meadows \n              I,","year":"2006","unstructured":"Meadows \n              I, \n            \n            \n              Gwaltney-Brant \n              S. \n            \n          \n          The 10 Most Common Toxicoses in Dogs. Vet Med2006:142\u20138."},{"key":"i1547-3317-53-4-236-b02","series-title":"Vet Clin North Am Small Anim Pract","first-page":"219","article-title":"An overview of trends in animal poisoning cases in the United States: 2002-2010","volume":"42","author":"McLean \n              MK,","year":"2012","unstructured":"McLean \n              MK, \n            \n            \n              Hansen \n              SR. \n            \n          \n          An overview of trends in animal poisoning cases in the United States: 2002-2010. Vet Clin North Am Small Anim Pract2012;42:219\u201328."},{"key":"i1547-3317-53-4-236-b03","series-title":"J Am Vet Med Assoc","first-page":"516","article-title":"Anticoagulant rodenticide screening in dogs: 123 cases (1996-2003)","volume":"242","author":"Waddell \n              LS,","year":"2013","unstructured":"Waddell \n              LS, \n            \n            \n              Poppenga \n              RH, \n            \n            \n              Drobatz \n              KJ. \n            \n          \n          Anticoagulant rodenticide screening in dogs: 123 cases (1996-2003). J Am Vet Med Assoc2013;242:516\u201321."},{"key":"i1547-3317-53-4-236-b04","series-title":"Vet Clin North Am Small Anim Pract","first-page":"115","article-title":"Diagnosis and therapy of anticoagulant rodenticide intoxications","volume":"18","author":"Mount \n              ME.","year":"1988","unstructured":"Mount \n              ME. \n            \n          \n          Diagnosis and therapy of anticoagulant rodenticide intoxications. Vet Clin North Am Small Anim Pract1988;18:115\u201330."},{"key":"i1547-3317-53-4-236-b05","series-title":"Br J Haematol","first-page":"506","article-title":"Survival Time of Prothrombin and Factors Vii, Ix and X after Completely Synthesis Blocking Doses of Coumarin Derivatives","volume":"9","author":"Hellemans \n              J,","year":"1963","unstructured":"Hellemans \n              J, \n            \n            \n              Vorlat \n              M, \n            \n            \n              Verstraete \n              M. \n            \n          \n          Survival Time of Prothrombin and Factors Vii, Ix and X after Completely Synthesis Blocking Doses of Coumarin Derivatives. Br J Haematol1963;9:506\u201312."},{"key":"i1547-3317-53-4-236-b06","series-title":"J Vet Intern Med","first-page":"23","article-title":"Coagulopathic effects and therapy of brodifacoum toxicosis in dogs","volume":"6","author":"Woody \n              BJ,","year":"1992","unstructured":"Woody \n              BJ, \n            \n            \n              Murphy \n              MJ, \n            \n            \n              Ray \n              AC, \n            \n            et al. \n          Coagulopathic effects and therapy of brodifacoum toxicosis in dogs. J Vet Intern Med1992;6:23\u20138."},{"key":"i1547-3317-53-4-236-b07","series-title":"Small Animal Critical Care Medicine. 2nd ed","first-page":"92","article-title":"Upper Airwy Disease","author":"Clark \n              DL.","year":"2015","unstructured":"Clark \n              DL. \n            \n          \n          Upper Airwy Disease. In: Silverstein DC HK, ed. Small Animal Critical Care Medicine. 2nd ed. St. Louis: Elsevier;2015:92\u2013104."},{"key":"i1547-3317-53-4-236-b08","series-title":"Small Animal Toxicology. 3rd ed","article-title":"Anticoagulant Rodenticides - Small Animal Toxicology","author":"Murphy \n              M.J.","year":"2013","unstructured":"Murphy \n              M.J. \n            \n          \n          Anticoagulant Rodenticides - Small Animal Toxicology. In: Peterson M, ed. Small Animal Toxicology. 3rd ed. St. Louis: Saunders;2013."},{"key":"i1547-3317-53-4-236-b09","series-title":"Vet Clin North Am Small Anim Pract","first-page":"349","article-title":"Common rodenticide toxicoses in small animals","volume":"42","author":"DeClementi \n              C,","year":"2012","unstructured":"DeClementi \n              C, \n            \n            \n              Sobczak \n              BR. \n            \n          \n          Common rodenticide toxicoses in small animals. Vet Clin North Am Small Anim Pract2012;42:349\u201360."},{"key":"i1547-3317-53-4-236-b10","series-title":"J Vet Diagn Invest","first-page":"66","article-title":"Case studies on second-generation anticoagulant rodenticide toxicities in nontarget species","volume":"1","author":"DuVall \n              MD,","year":"1989","unstructured":"DuVall \n              MD, \n            \n            \n              Murphy \n              MJ, \n            \n            \n              Ray \n              AC, \n            \n            et al. \n          Case studies on second-generation anticoagulant rodenticide toxicities in nontarget species. J Vet Diagn Invest1989;1:66\u20138."},{"key":"i1547-3317-53-4-236-b11","series-title":"Veterinary Clinical Biochemistry of Domestic Animals. 6th ed","first-page":"286","article-title":"Hemostasis - Vet Clin Biochem of Domestic Animals","author":"Gentry \n              P,","year":"2008","unstructured":"Gentry \n              P, \n            \n            \n              Burgess \n              H, \n            \n            \n              Wood \n              D. \n            \n          \n          Hemostasis - Vet Clin Biochem of Domestic Animals. In: Kaneko JJ HJ, Bruss ML, eds. Veterinary Clinical Biochemistry of Domestic Animals. 6th ed. Burlington, MA: Elsevier;2008:286\u2013330."},{"key":"i1547-3317-53-4-236-b12","series-title":"Vet Ophthalmol","first-page":"73","article-title":"Anticoagulant rodenticide toxicity in six dogs presenting for ocular disease","volume":"1","author":"Griggs \n              AN,","year":"2015","unstructured":"Griggs \n              AN, \n            \n            \n              Allbaugh \n              RA, \n            \n            \n              Tofflemire \n              KL, \n            \n            et al. \n          Anticoagulant rodenticide toxicity in six dogs presenting for ocular disease. Vet Ophthalmol2015;1:73\u201380."},{"key":"i1547-3317-53-4-236-b13","series-title":"Clinical Veterinary Advisor: Dogs and Cats","first-page":"1028","article-title":"Upper Airway Obstruction","volume":"3rd ed","author":"Megan \n              WD.","year":"2015","unstructured":"Megan \n              WD. \n            \n          \n          Upper Airway Obstruction. In:Etienne Cote D, ed. Clinical Veterinary Advisor: Dogs and Cats. 3rd ed. St. Louis: Elsevier-Mosby; 2015:1028\u20139."},{"key":"i1547-3317-53-4-236-b14","series-title":"Manual of Small Animal Emergency and Critical Care Medicine. 2nd ed","first-page":"139","article-title":"Respiratory Emergencies","author":"Drobatz \n              KJ.","year":"2012","unstructured":"Drobatz \n              KJ. \n            \n          \n          Respiratory Emergencies. In: Macintire DK DK, Haskins SC, Saxon WD, ed. Manual of Small Animal Emergency and Critical Care Medicine. 2nd ed. Ames, IA: Wiley-Blackwell;2012:139\u201391."},{"key":"i1547-3317-53-4-236-b15","series-title":"Blackwell's Five-Minute Veterinary Consult Clinical Companion Small Animal Emergency and Critical Care. 1st ed","first-page":"813","article-title":"Tracheal Collapse","author":"Bach \n              JF.","year":"2010","unstructured":"Bach \n              JF. \n            \n          \n          Tracheal Collapse. In: Mazzaferro EM(ed). Blackwell's Five-Minute Veterinary Consult Clinical Companion Small Animal Emergency and Critical Care. 1st ed. Ames, IA: Blackwell Publishing Ltd.;2010:813\u20138."},{"key":"i1547-3317-53-4-236-b16","series-title":"J Am Vet Med Assoc","first-page":"352","article-title":"Laryngeal obstruction secondary to brodifacoum toxicosis in a dog","volume":"208","author":"Peterson \n              J,","year":"1996","unstructured":"Peterson \n              J, \n            \n            \n              Streeter \n              V. \n            \n          \n          Laryngeal obstruction secondary to brodifacoum toxicosis in a dog. J Am Vet Med Assoc1996;208:352\u20135."},{"key":"i1547-3317-53-4-236-b17","series-title":"J Small Anim Pract","first-page":"577","article-title":"Acute tracheal obstruction associated with anticoagulant rodenticide intoxication in a dog","volume":"40","author":"Blocker \n              TL,","year":"1999","unstructured":"Blocker \n              TL, \n            \n            \n              Roberts \n              BK. \n            \n          \n          Acute tracheal obstruction associated with anticoagulant rodenticide intoxication in a dog. J Small Anim Pract1999;40:577\u201380."},{"key":"i1547-3317-53-4-236-b18","series-title":"J Small Anim Pract","first-page":"161","article-title":"Intramural tracheal haematoma causing acute respiratory obstruction in a dog","volume":"47","author":"Pink \n              JJ.","year":"2006","unstructured":"Pink \n              JJ. \n            \n          \n          Intramural tracheal haematoma causing acute respiratory obstruction in a dog. J Small Anim Pract2006;47:161\u20134."},{"key":"i1547-3317-53-4-236-b19","series-title":"Vet Radiol Ultrasound","first-page":"391","article-title":"Thoracic radiographic features of anticoagulant rodenticide toxicity in fourteen dogs","volume":"34","author":"Berry \n              CR,","year":"1993","unstructured":"Berry \n              CR, \n            \n            \n              Gallaway \n              A, \n            \n            \n              Thrall \n              DE, \n            \n            \n              Carlisle \n              C. \n            \n          \n          Thoracic radiographic features of anticoagulant rodenticide toxicity in fourteen dogs. Vet Radiol Ultrasound1993;34:391\u20136."},{"key":"i1547-3317-53-4-236-b20","series-title":"Am J Med","first-page":"460","article-title":"Unusual complications in the course of anticoagulant therapy","volume":"46","author":"Reussi \n              C,","year":"1969","unstructured":"Reussi \n              C, \n            \n            \n              Schiavi \n              JE, \n            \n            \n              Altman \n              R, \n            \n            et al. \n          Unusual complications in the course of anticoagulant therapy. Am J Med1969;46:460\u20133."},{"key":"i1547-3317-53-4-236-b21","series-title":"Forensic Sci Int","first-page":"13","article-title":"'Superwarfarin' poisoning leading to prolonged coagulopathy","volume":"78","author":"Hui \n              CH,","year":"1996","unstructured":"Hui \n              CH, \n            \n            \n              Lie \n              A, \n            \n            \n              Lam \n              CK, \n            \n            et al. \n          'Superwarfarin' poisoning leading to prolonged coagulopathy. Forensic Sci Int1996;78:13\u20138."},{"key":"i1547-3317-53-4-236-b22","series-title":"Am J Emerg Med","first-page":"674","article-title":"Spontaneous bilateral arytenoid hematoma in a patient on warfarin","volume":"16","author":"Jandreau \n              SW,","year":"1998","unstructured":"Jandreau \n              SW, \n            \n            \n              Mayer \n              D. \n            \n          \n          Spontaneous bilateral arytenoid hematoma in a patient on warfarin. Am J Emerg Med1998;16:674\u20136."},{"key":"i1547-3317-53-4-236-b23","series-title":"J Emerg Med","first-page":"389","article-title":"Anticoagulation and spontaneous retropharyngeal hematoma","volume":"24","author":"Bloom \n              DC,","year":"2003","unstructured":"Bloom \n              DC, \n            \n            \n              Haegen \n              T, \n            \n            \n              Keefe \n              MA. \n            \n          \n          Anticoagulation and spontaneous retropharyngeal hematoma. J Emerg Med2003;24:389\u201394."},{"key":"i1547-3317-53-4-236-b24","series-title":"Can J Anaesth","first-page":"526","article-title":"Epiglottic hematoma: a rare occurrence after tracheal intubation","volume":"53","author":"Hatzakorzian \n              R,","year":"2006","unstructured":"Hatzakorzian \n              R, \n            \n            \n              Shan \n              WL, \n            \n            \n              Backman \n              SB. \n            \n          \n          Epiglottic hematoma: a rare occurrence after tracheal intubation. Can J Anaesth2006;53:526\u20137."},{"key":"i1547-3317-53-4-236-b25","series-title":"J Laryngol Otol","first-page":"381","article-title":"Life-threatening cervico-mediastinal haematoma after carotid sinus massage","volume":"105","author":"Thomas \n              MD,","year":"1991","unstructured":"Thomas \n              MD, \n            \n            \n              Torres \n              A, \n            \n            \n              Garcia-Polo \n              J, \n            \n            et al. \n          Life-threatening cervico-mediastinal haematoma after carotid sinus massage. J Laryngol Otol1991;105:381\u20133."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/53\/4\/article-p236.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/53\/4\/236\/1329375\/jaaha-ms-6658.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/53\/4\/article-p236.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/53\/4\/article-p236.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:01:11Z","timestamp":1763740871000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/53\/4\/article-p236.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":25,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-6658","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}