{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:59:38Z","timestamp":1763747978860,"version":"3.45.0"},"reference-count":13,"publisher":"American Animal Hospital Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In both dogs and cats, the most common cranial mediastinal masses (CMMs) are lymphoma and thymic epithelial tumors (TETs). Pretreatment differentiation of these tumors using fine needle aspiration or biopsy is essential because lymphomas are treated medically, whereas TETs are treated surgically. The purpose of this retrospective study was to determine whether thoracic radiographic findings can be used to aid clinicians in preliminarily differentiating the two tumor types before cytology or histopathology results become available. Medical records, available cytologic or histologic samples, and thoracic radiographs were evaluated for 62 dogs and 28 cats. Seventeen radiographic criteria were assessed by two examiners, and regression modeling was performed to test for significant predictors of tumor type. In dogs, CMMs with at least two well-defined radiographic margins on a lateral view and CMMs causing a rightward shift of the cardiac silhouette on a ventrodorsal or dorsoventral view were significantly more likely to be TETs than lymphomas (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .001 and\n                    <jats:italic>P<\/jats:italic>\n                    &lt; .01, respectively). No significant predictive variables were identified in cats. Radiographic findings do not eliminate the need for invasive sampling, but in dogs, they may guide the clinician in providing preliminary information to owners regarding the staging and therapeutic measures that may eventually be recommended.\n                  <\/jats:p>","DOI":"10.5326\/jaaha-ms-6907","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T10:48:53Z","timestamp":1558090133000},"page":"187-193","source":"Crossref","is-referenced-by-count":5,"title":["Radiographic Differentiation of Cranial Mediastinal Lymphomas from Thymic Epithelial Tumors in Dogs and Cats"],"prefix":"10.5326","volume":"55","author":[{"given":"Trisha J.","family":"Oura","sequence":"first","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip E.","family":"Hamel","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel H.","family":"Jennings","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perry J.","family":"Bain","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis E.","family":"Jennings","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Berg","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences (T.J.O., P.E.H., J.B.), and Department of Biomedical Sciences (S.H.J., P.J.B.), Cummings School of Veterinary Medicine, Tufts University, Grafton, Massachusetts; and Independent Consultant, Libertyville, Illinois (D.E.J.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"Withrow and MacEwen's Small Animal Clinical Oncology","first-page":"608","article-title":"Hematopoietic tumors","author":"Vail\n              DM","year":"2013","unstructured":"Vail\n              DM\n            , PinkertonME, YoungKM. 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Miller's Anatomy of the Dog. 3rd ed.Philadelphia: Saunders; 1993:753\u201355."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/55\/4\/article-p187.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/55\/4\/187\/2466225\/jaaha-ms-6907.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/55\/4\/article-p187.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/55\/4\/article-p187.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:03:43Z","timestamp":1763741023000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/55\/4\/article-p187.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":13,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-6907","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"type":"print","value":"0587-2871"},{"type":"electronic","value":"1547-3317"}],"subject":[],"published":{"date-parts":[[2019]]}}}