{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:40:20Z","timestamp":1770223220599,"version":"3.49.0"},"reference-count":20,"publisher":"American Animal Hospital Association","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 6 yr old neutered male German shepherd dog was evaluated at a veterinary referral hospital following diagnosis of uroabdomen of unknown origin. A positive-contrast retrograde urethrogram identified diffusely irregular margins of the urinary bladder but no active leakage of urine into the peritoneal cavity. An abdominal ultrasound identified severe thickening and loss of wall layering of the apex of the bladder. The dog was initially managed with an indwelling urinary catheter; however, when the catheter was removed 5 days later, the dog developed a recurrent uroabdomen after an episode of dysuria. Subsequent surgical exploration identified numerous (&gt;5), small (1\u20132 cm), black cyst-like nodules within the bladder wall at the apex of the bladder. A partial cystectomy, removing approximately 65% of the cranial bladder, was performed. Histopathology and immunohistochemistry of the bladder identified hemangiosarcoma of the bladder wall with chronic neutrophilic and hemorrhagic cystitis. The dog recovered from surgery without major complication and is still alive 9 mo following surgery. To the authors\u2019 knowledge, this is the first report of successful treatment of canine bladder hemangiosarcoma by partial cystectomy in a dog.<\/jats:p>","DOI":"10.5326\/jaaha-ms-6910","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T11:59:03Z","timestamp":1589543943000},"page":"231-235","source":"Crossref","is-referenced-by-count":3,"title":["Successful Treatment of Urinary Bladder Hemangiosarcoma by Partial Cystectomy in a Dog"],"prefix":"10.5326","volume":"56","author":[{"given":"Sarah","family":"Townsend","sequence":"first","affiliation":[{"name":"From the University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penny J.","family":"Regier","sequence":"additional","affiliation":[{"name":"From the University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil N.","family":"More","sequence":"additional","affiliation":[{"name":"From the University of Florida, Gainesville, Florida."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"Vet J","first-page":"217","article-title":"Management of transitional cell carcinoma of the urinary bladder in dogs: a review","volume":"205","author":"Fulkerson\n              CM","year":"2015","unstructured":"Fulkerson\n              CM\n            , KnappDW. Management of transitional cell carcinoma of the urinary bladder in dogs: a review. Vet J2015;205:217\u201325."},{"key":"bib2","series-title":"J Vet Intern Med","first-page":"136","article-title":"Canine transitional cell carcinoma","volume":"17","author":"Mutsaers\n              AJ","year":"2003","unstructured":"Mutsaers\n              AJ\n            , WidmerWR, KnappDW. Canine transitional cell carcinoma. J Vet Intern Med2003;17:136\u201344."},{"key":"bib3","series-title":"J Vet Intern Med","first-page":"145","article-title":"Canine bladder and urethral tumors: a retrospective study of 115 cases (1980-1985)","volume":"6","author":"Norris\n              AM","year":"2001","unstructured":"Norris\n              AM\n            , LaingEJ, ValliVE, et al.\n          Canine bladder and urethral tumors: a retrospective study of 115 cases (1980-1985). J Vet Intern Med2001;6:145\u201353."},{"key":"bib4","series-title":"J Am Vet Med Assoc","first-page":"56","article-title":"Canine hemangiosarcoma: retrospective analysis of 104 cases","volume":"186","author":"Brown\n              NO","year":"1985","unstructured":"Brown\n              NO\n            , PatnaikAK, MacEwenEG. Canine hemangiosarcoma: retrospective analysis of 104 cases. J Am Vet Med Assoc1985;186:56\u20138."},{"key":"bib5","series-title":"J Am Vet Med Assoc","first-page":"655","article-title":"Hemangiosarcoma of the urinary bladder in a dog","volume":"192","author":"Martinez\n              SA","year":"1988","unstructured":"Martinez\n              SA\n            , SchulmanAJ. Hemangiosarcoma of the urinary bladder in a dog. J Am Vet Med Assoc1988;192:655\u20136."},{"key":"bib6","series-title":"Vet Rec","first-page":"408","article-title":"Breed prevalence and sites of haemangioma and haemangiosarcoma in dogs","volume":"129","author":"Srebernik\n              N","year":"1991","unstructured":"Srebernik\n              N\n            , ApplebyEC. Breed prevalence and sites of haemangioma and haemangiosarcoma in dogs. Vet Rec1991;129:408\u20139."},{"key":"bib7","series-title":"Aust Vet J","first-page":"215","article-title":"Hemangiosarcoma of the urinary bladder in a dog","volume":"82","author":"Liptak\n              JM","year":"2004","unstructured":"Liptak\n              JM\n            , DernellWS, WithrowSJ. Hemangiosarcoma of the urinary bladder in a dog. Aust Vet J2004;82:215\u20137."},{"key":"bib8","series-title":"J Vet Diagn Invest","first-page":"522","article-title":"A retrospective study of visceral and nonvisceral hemangiosarcoma and hemangiomas in domestic animals","volume":"16","author":"Schultheiss\n              PC","year":"2004","unstructured":"Schultheiss\n              PC\n            \n          . A retrospective study of visceral and nonvisceral hemangiosarcoma and hemangiomas in domestic animals. J Vet Diagn Invest2004;16:522\u20136."},{"key":"bib9","series-title":"J Comp Pathol","first-page":"585","article-title":"Haemangiosarcoma in dogs","volume":"88","author":"Okansen\n              A","year":"1978","unstructured":"Okansen\n              A\n            \n          . Haemangiosarcoma in dogs. J Comp Pathol1978;88:585\u201395."},{"key":"bib10","series-title":"J Small Anim Pract","first-page":"426","article-title":"A review of pathological diagnoses made from 87 canine splenic biopsies","volume":"36","author":"Day\n              MJ","year":"1995","unstructured":"Day\n              MJ\n            , LuckeVM, PearsonH. A review of pathological diagnoses made from 87 canine splenic biopsies. J Small Anim Pract1995;36:426\u201333."},{"key":"bib11","series-title":"J Comp Pathol","first-page":"18","article-title":"Primary and secondary heart tumours in dogs and cats","volume":"136","author":"Aupperle\n              H","year":"2007","unstructured":"Aupperle\n              H\n            , MarzI, EllenbergerC, et al.\n          Primary and secondary heart tumours in dogs and cats. J Comp Pathol2007;136:18\u201326."},{"key":"bib12","series-title":"J Am Vet Med Assoc","first-page":"829","article-title":"Prevalence, type and importance of splenic disease in dogs: 1,480 cases (1985-1989)","volume":"200","author":"Spangler\n              WL","year":"1992","unstructured":"Spangler\n              WL\n            , CulbertsonMR. Prevalence, type and importance of splenic disease in dogs: 1,480 cases (1985-1989). J Am Vet Med Assoc1992;200:829\u201334."},{"key":"bib13","series-title":"J Vet Intern Med","first-page":"479","article-title":"Treatment of canine hemangiosarcoma: 2000 and beyond","volume":"14","author":"Clifford\n              CA","year":"2000","unstructured":"Clifford\n              CA\n            , MackinAJ, HenryCJ. Treatment of canine hemangiosarcoma: 2000 and beyond. J Vet Intern Med2000;14:479\u201385."},{"key":"bib14","series-title":"J Am Anim Hosp Assoc","first-page":"417","article-title":"Prognosis for dogs with stage I or II splenic hemangiosarcoma treated by splenectomy alone: 32 cases (1991\u20131993)","volume":"34","author":"Wood\n              CA","year":"1998","unstructured":"Wood\n              CA\n            , MooreAS, GliattoJM, et al.\n          Prognosis for dogs with stage I or II splenic hemangiosarcoma treated by splenectomy alone: 32 cases (1991\u20131993). J Am Anim Hosp Assoc1998;34:417\u201321."},{"key":"bib15","series-title":"J Vet Emerg Crit Care","first-page":"275","article-title":"Evaluation of abdominal fluid: peripheral blood creatinine and potassium ratios for diagnosis of uroperitoneum in dogs","volume":"11","author":"Schmiedt\n              C","year":"2001","unstructured":"Schmiedt\n              C\n            , TobiasK, OttoC. Evaluation of abdominal fluid: peripheral blood creatinine and potassium ratios for diagnosis of uroperitoneum in dogs. J Vet Emerg Crit Care2001;11:275\u201380."},{"key":"bib16","series-title":"Urology","first-page":"778","article-title":"Angiosarcoma of the bladder: a review","volume":"52","author":"Engel\n              JD","year":"1998","unstructured":"Engel\n              JD\n            , KuzelTM, MoceanuMC, et al.\n          Angiosarcoma of the bladder: a review. Urology1998;52:778\u201384."},{"key":"bib17","series-title":"Cancer","first-page":"777","article-title":"Radiation-induced angiosarcoma","volume":"60","author":"Nanus\n              DM","year":"1987","unstructured":"Nanus\n              DM\n            , KelsenD, ClarkDG. Radiation-induced angiosarcoma. Cancer1987;60:777\u20139."},{"key":"bib18","series-title":"South Med J","first-page":"1434","article-title":"Vaginal and bladder angiosarcoma after therapeutic irradiation","volume":"82","author":"Morgan\n              MA","year":"1989","unstructured":"Morgan\n              MA\n            , MoutosDM, PippittCH. Vaginal and bladder angiosarcoma after therapeutic irradiation. South Med J1989;82:1434\u20136."},{"key":"bib19","series-title":"J Am Med Assoc","first-page":"1178","article-title":"Subtotal cystectomy and total bladder regeneration in treatment of bladder cancer","volume":"168","author":"Baker\n              R","year":"1985","unstructured":"Baker\n              R\n            , KelleyT, TehantT, et al.\n          Subtotal cystectomy and total bladder regeneration in treatment of bladder cancer. J Am Med Assoc1985;168:1178\u201385."},{"key":"bib20","series-title":"J Small Anim Pract","first-page":"480","article-title":"Partial cystectomy for urinary bladder neoplasia: surgical technique and outcome in 11 dogs","volume":"37","author":"Stone\n              EA","year":"1996","unstructured":"Stone\n              EA\n            , GeorgeTF, GilsonSD, et al.\n          Partial cystectomy for urinary bladder neoplasia: surgical technique and outcome in 11 dogs. 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