{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:29:18Z","timestamp":1778279358002,"version":"3.51.4"},"reference-count":49,"publisher":"American Animal Hospital Association","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Knowledge regarding the etiology and prognosis for canine megaesophagus (ME) is currently limited to small case series that may now be out of date in light of recent advances in the understanding of neurological syndromes and the availability of advanced diagnostic testing. Ninety-nine dogs diagnosed with nonstructural ME were included. Congenital idiopathic ME was present in 10 cases, with complete resolution of clinical signs in a single case. Eighty-nine cases were considered acquired, with most cases being either idiopathic (42.7%) or associated with myasthenia gravis (38.2%). Idiopathic cases represented a smaller percentage of acquired ME than previously reported. Death or euthanasia directly related to ME occurred in almost 50% of acquired cases, whereas clinical signs persisted in \u223c20% of cases and resolved in 30% of cases. A diagnosis of an underlying etiology, in particular myasthenia gravis, was associated with a better outcome in acquired ME. ME continues to be a challenging condition to manage, with a guarded-to-poor prognosis, particularly when an underlying etiology is not identified. Thorough diagnostic testing for an underlying neurological disorder is important in cases with ME as this may allow institution of appropriate treatment and the potential for a better prognosis.<\/jats:p>","DOI":"10.5326\/jaaha-ms-6955","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T19:11:26Z","timestamp":1573585886000},"page":"7-16","source":"Crossref","is-referenced-by-count":3,"title":["Canine Nonstructural Megaesophagus as a Clinical Sign of Potential Neurological Disease: 99 Cases"],"prefix":"10.5326","volume":"56","author":[{"given":"Sergio A.","family":"Gomes","sequence":"first","affiliation":[{"name":"From Dovecote Veterinary Hospital, Derby, United Kingdom (S.A.G.); Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, University of Ghent, Ghent, Belgium (L.V.H., A.V.H.); Anderson Moores Veterinary Specialists, Winchester, United Kingdom (E.J.I.); and Department of Veterinary Medicine, The Queen\u2019s Veterinary School, University of Cambridge, Cambridge, United Kingdom (A.V.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Van Ham","sequence":"additional","affiliation":[{"name":"From Dovecote Veterinary Hospital, Derby, United Kingdom (S.A.G.); Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, University of Ghent, Ghent, Belgium (L.V.H., A.V.H.); Anderson Moores Veterinary Specialists, Winchester, United Kingdom (E.J.I.); and Department of Veterinary Medicine, The Queen\u2019s Veterinary School, University of Cambridge, Cambridge, United Kingdom (A.V.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anouk","family":"Van Ham","sequence":"additional","affiliation":[{"name":"From Dovecote Veterinary Hospital, Derby, United Kingdom (S.A.G.); Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, University of Ghent, Ghent, Belgium (L.V.H., A.V.H.); Anderson Moores Veterinary Specialists, Winchester, United Kingdom (E.J.I.); and Department of Veterinary Medicine, The Queen\u2019s Veterinary School, University of Cambridge, Cambridge, United Kingdom (A.V.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward J.","family":"Ives","sequence":"additional","affiliation":[{"name":"From Dovecote Veterinary Hospital, Derby, United Kingdom (S.A.G.); Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, University of Ghent, Ghent, Belgium (L.V.H., A.V.H.); Anderson Moores Veterinary Specialists, Winchester, United Kingdom (E.J.I.); and Department of Veterinary Medicine, The Queen\u2019s Veterinary School, University of Cambridge, Cambridge, United Kingdom (A.V.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An","family":"Vanhaesebrouck","sequence":"additional","affiliation":[{"name":"From Dovecote Veterinary Hospital, Derby, United Kingdom (S.A.G.); Department of Medicine and Clinical Biology of Small Animals, Faculty of Veterinary Medicine, University of Ghent, Ghent, Belgium (L.V.H., A.V.H.); Anderson Moores Veterinary Specialists, Winchester, United Kingdom (E.J.I.); and Department of Veterinary Medicine, The Queen\u2019s Veterinary School, University of Cambridge, Cambridge, United Kingdom (A.V.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"bib1","series-title":"J Am Anim Hosp Assoc","first-page":"33","article-title":"Megaoesophagus in the dog: A review of 50 cases","volume":"21","author":"Boudrieau\n              RJ","year":"1985","unstructured":"Boudrieau\n              RJ\n            , Rogers, WA. Megaoesophagus in the dog: A review of 50 cases. J Am Anim Hosp Assoc1985;21:33\u201340."},{"key":"bib2","series-title":"J Am Vet Med Assoc","first-page":"1406","article-title":"Risk factors for acquired megaoesophagus in dogs","volume":"211","author":"Gaynor\n              AR","year":"1997","unstructured":"Gaynor\n              AR\n            , ShoferFS, WashabauRJ. Risk factors for acquired megaoesophagus in dogs. J Am Vet Med Assoc1997:211:1406\u201312."},{"key":"bib3","series-title":"Semin Vet Med Surg (Small Anim)","first-page":"37","article-title":"Megaoesophagus in the dog and cat","volume":"5","author":"Guilford, WG","year":"1990","unstructured":"Guilford, WG\n          . Megaoesophagus in the dog and cat. Semin Vet Med Surg (Small Anim)1990;5:37\u201345."},{"key":"bib4","series-title":"Vet Clin North Am Small Anim Pract","first-page":"1007","article-title":"Gastrointestinal motility disorders and gastrointestinal prokinetic therapy","volume":"33","author":"Washabau\n              R","year":"2003","unstructured":"Washabau\n              R\n            \n          . Gastrointestinal motility disorders and gastrointestinal prokinetic therapy. Vet Clin North Am Small Anim Pract2003;33:1007\u201328."},{"key":"bib5","series-title":"Kirk\u2019s Current Vet Therapy XIV","first-page":"486","article-title":"Canine Megaesophagus","author":"Johnson\n              BM","year":"2008","unstructured":"Johnson\n              BM\n            , DeNovoRC, MearsEA. Canine Megaesophagus. In: BonaguraJD, TwedtDC, eds. Kirk\u2019s Current Vet Therapy XIV. Philadelphia: WB Saunders; 2008:486\u201392."},{"key":"bib6","series-title":"Megaoesophagus. Compend Contin Educ Vet","first-page":"E1","volume":"34","author":"Mace\n              S","year":"2012","unstructured":"Mace\n              S\n            , SheltonG, EddlestoneS. Megaoesophagus. Compend Contin Educ Vet2012;34:E1\u20138."},{"key":"bib7","series-title":"Vlaams Diergeneeskd Tijdschr","first-page":"388","article-title":"Megaoesofagus bij hond en kat [Megaoesophagus in the dog and cat]","volume":"78","author":"Van Ham\n              A","year":"2009","unstructured":"Van Ham\n              A\n            , VanhaesebrouckA, PolisI, et al.\n          Megaoesofagus bij hond en kat [Megaoesophagus in the dog and cat]. Vlaams Diergeneeskd Tijdschr2009;78:388\u201399."},{"key":"bib8","series-title":"J Am Vet Med Assoc","first-page":"1622","article-title":"Clinical factors associated with death before discharge and overall survival time in dogs with generalized megaesophagus","volume":"238","author":"McBrearty\n              AR","year":"2011","unstructured":"McBrearty\n              AR\n            , RamseyIK, CourcierEA, et al.\n          Clinical factors associated with death before discharge and overall survival time in dogs with generalized megaesophagus. J Am Vet Med Assoc2011;238:1622\u201328."},{"key":"bib9","series-title":"Brain Res","first-page":"125","article-title":"The origins of innervation of the oesophagus of the dog","volume":"326","author":"Hudson\n              L","year":"1985","unstructured":"Hudson\n              L\n            , CummingsJ. The origins of innervation of the oesophagus of the dog. Brain Res1985;326:125\u201336."},{"key":"bib10","series-title":"Am J Vet Res","first-page":"906","article-title":"Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaoesophagus","volume":"57","author":"Holland\n              C","year":"1996","unstructured":"Holland\n              C\n            , SatchellP, FarrowB. Vagal esophagomotor nerve function and esophageal motor performance in dogs with congenital idiopathic megaoesophagus. Am J Vet Res1996;57:906\u201313."},{"key":"bib11","series-title":"Miller\u2019s Anatomy of the Dog","first-page":"658","article-title":"The brain","author":"Fletcher\n              TF","year":"2013","unstructured":"Fletcher\n              TF\n            , BeitzAJ. The brain. In: EvansHE, de LahuntaA, eds. Miller\u2019s Anatomy of the Dog. 4th ed.St. Louis: Saunders; 2013:658\u2013707."},{"key":"bib12","series-title":"Veterinary Neuroanatomy","first-page":"91","article-title":"Cranial nerves","author":"Thomson\n              CE","year":"2012","unstructured":"Thomson\n              CE\n            , HahnCN. Cranial nerves. In: Veterinary Neuroanatomy. 1st ed.Edinburgh (UK): Elsevier-Saunders; 2012:91\u2013108."},{"key":"bib13","series-title":"J Surg Res","first-page":"160","article-title":"Structure of the canine oesophagus and its sphincters","volume":"4","author":"Mann\n              C","year":"1964","unstructured":"Mann\n              C\n            , ShorterR. Structure of the canine oesophagus and its sphincters. J Surg Res1964;4:160\u20133."},{"key":"bib14","series-title":"J Am Vet Med Assoc","first-page":"411","article-title":"Evaluation of lower motor neuron function in two dogs with megaoesophagus","volume":"169","author":"Strombeck\n              DR","year":"1976","unstructured":"Strombeck\n              DR\n            , TroyaL. Evaluation of lower motor neuron function in two dogs with megaoesophagus. J Am Vet Med Assoc1976;169:411\u20134."},{"key":"bib15","series-title":"Dig Dis Sci","first-page":"76","article-title":"Assessment of the neural defect in a dog with idiopathic megaoesophagus","volume":"32","author":"Tan\n              B","year":"1987","unstructured":"Tan\n              B\n            , DiamantN. Assessment of the neural defect in a dog with idiopathic megaoesophagus. Dig Dis Sci1987;32:76\u201385."},{"key":"bib16","series-title":"Auton Neurosci","first-page":"18","article-title":"Selective vagal afferent dysfunction in dogs with congenital idiopathic megaooesophagus","volume":"99","author":"Holland\n              C","year":"2002","unstructured":"Holland\n              C\n            , SatchellP, FarrowB. Selective vagal afferent dysfunction in dogs with congenital idiopathic megaooesophagus. Auton Neurosci2002;99:18\u201323."},{"key":"bib17","series-title":"Aust Vet J","first-page":"414","article-title":"Oesophageal compliance in naturally occurring canine megaooesophagus","volume":"370","author":"Holland\n              C","year":"1993","unstructured":"Holland\n              C\n            , SatchellP, FarrowB. Oesophageal compliance in naturally occurring canine megaooesophagus. Aust Vet J1993;370:414\u201320."},{"key":"bib18","series-title":"J Vet Intern Med","first-page":"1314","article-title":"Esophageal Dysmotility in Young Dogs","volume":"20","author":"Bexfield\n              N","year":"2006","unstructured":"Bexfield\n              N\n            , WatsonP, Herrtage, M. Esophageal Dysmotility in Young Dogs. J Vet Intern Med2006;20:1314\u20138."},{"key":"bib19","series-title":"Can Vet J","first-page":"232","article-title":"Esophageal achalasia and secondary megaesophagus in a dog","volume":"44","author":"Boria\n              PA","year":"2003","unstructured":"Boria\n              PA\n            , WebsterCRL, BergJ. Esophageal achalasia and secondary megaesophagus in a dog. Can Vet J2003;44:232\u20134."},{"key":"bib20","series-title":"J Vet Intern Med","first-page":"661","article-title":"Achalasia-like disease with esophageal pressurization in a myasthenic dog","volume":"28","author":"Kempf\n              J","year":"2014","unstructured":"Kempf\n              J\n            , BeckmannK, KookPH. Achalasia-like disease with esophageal pressurization in a myasthenic dog. J Vet Intern Med2014;28:661\u20135."},{"key":"bib21","series-title":"Gastroenterol","first-page":"216","article-title":"Manometric characteristics of idiopathic megaesophagus in the dog: An unsuitable animal model for Achalasia in man","volume":"65","author":"Diamant\n              N","year":"1973","unstructured":"Diamant\n              N\n            , SzczepanskiM, MuiH. Manometric characteristics of idiopathic megaesophagus in the dog: An unsuitable animal model for Achalasia in man. Gastroenterol1973;65:216\u201323."},{"key":"bib22","series-title":"J Am Vet Med Assoc","first-page":"443","article-title":"Megaoesophagus in the dog: A clinical survey of 79 cases","volume":"165","author":"Harvey, CE","year":"1974","unstructured":"Harvey, CE, O\u2019Brien, JA, Durie, VR, et al.\n          Megaoesophagus in the dog: A clinical survey of 79 cases. J Am Vet Med Assoc1974;165:443\u20136."},{"key":"bib23","series-title":"J Small Anim Pract","first-page":"256","article-title":"Use of radiographic measurements in distinguishing myasthenia gravis from other causes of canine megaooesophagus","volume":"47","author":"Wray\n              J","year":"2006","unstructured":"Wray\n              J\n            , SparkesA. Use of radiographic measurements in distinguishing myasthenia gravis from other causes of canine megaooesophagus. J Small Anim Pract2006;47:256\u201363."},{"key":"bib24","series-title":"Schweiz Arch Tierheilkd","first-page":"236","article-title":"\u00dcberlebensdauer bei verschiedenen Formen des kaninen Mega\u00f6sophagus [Survival duration for different forms of canine megaesophagus]","volume":"153","author":"Sch\u00f6nfelder\n              J","year":"2011","unstructured":"Sch\u00f6nfelder\n              J\n            , Sch\u00f6nfelderA, NeigerR. \u00dcberlebensdauer bei verschiedenen Formen des kaninen Mega\u00f6sophagus [Survival duration for different forms of canine megaesophagus]. Schweiz Arch Tierheilkd2011;153:236\u20138."},{"key":"bib25","series-title":"Vet Clin North Am Small Anim Pract","first-page":"189","article-title":"Myasthenia gravis and disorders of neuromuscular transmission","volume":"32","author":"Shelton\n              GD","year":"2002","unstructured":"Shelton\n              GD\n            \n          . Myasthenia gravis and disorders of neuromuscular transmission. Vet Clin North Am Small Anim Pract2002;32:189\u2013206"},{"key":"bib26","series-title":"J Am Vet Med Assoc","first-page":"1310","article-title":"Myopathy associated with hyperadrenocorticism in the dog","volume":"174","author":"Greene\n              CE","year":"1979","unstructured":"Greene\n              CE\n            , LorenzMD, MunnellJF, et al.\n          Myopathy associated with hyperadrenocorticism in the dog. J Am Vet Med Assoc1979;174:1310."},{"key":"bib27","series-title":"Vet Clin North Am Small Anim Pract","first-page":"125","article-title":"Neuromuscular complications in endocrine and metabolic disorders","volume":"32","author":"Platt\n              SR","year":"2002","unstructured":"Platt\n              SR\n            \n          . Neuromuscular complications in endocrine and metabolic disorders. Vet Clin North Am Small Anim Pract2002;32:125\u201346."},{"key":"bib28","series-title":"Vet Immunol Immunopathol","first-page":"239","article-title":"Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models","volume":"69","author":"Shelton\n              GD","year":"1999","unstructured":"Shelton\n              GD\n            \n          . Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models. Vet Immunol Immunopathol1999;69:239\u201349."},{"key":"bib29","series-title":"Vet Rec","first-page":"17","article-title":"Acquired idiopathic laryngeal paralysis as a prominent feature of generalized neuromuscular disease in 39 dogs","volume":"158","author":"Jeffery\n              N","year":"2006","unstructured":"Jeffery\n              N\n            , TalbotC, SmithP, et al.\n          Acquired idiopathic laryngeal paralysis as a prominent feature of generalized neuromuscular disease in 39 dogs. Vet Rec2006;158:17\u201321."},{"key":"bib30","series-title":"J Small Anim Pract","first-page":"144","article-title":"Laryngeal paralysis-polyneuropathy complex in young related Pyrenean mountain dogs","volume":"47","author":"Gabriel\n              A","year":"2006","unstructured":"Gabriel\n              A\n            , PonceletL, Van HamL, et al.\n          Laryngeal paralysis-polyneuropathy complex in young related Pyrenean mountain dogs. J Small Anim Pract2006;47:144\u20139."},{"key":"bib31","series-title":"Vet Surg","first-page":"139","article-title":"Esophageal Dysfunction in Dogs with Idiopathic Laryngeal Paralysis: A Controlled Cohort Study","volume":"39","author":"Stanley\n              B","year":"2010","unstructured":"Stanley\n              B\n            , HauptmanJ, FritzM, et al.\n          Esophageal Dysfunction in Dogs with Idiopathic Laryngeal Paralysis: A Controlled Cohort Study. Vet Surg2010; 39:139\u201349."},{"key":"bib32","series-title":"J Vet Intern Med","first-page":"2814","article-title":"Acquired myasthenia gravis. Selective involvement of esophageal, pharyngeal and facial muscles","volume":"4","author":"Shelton\n              GD","year":"1990","unstructured":"Shelton\n              GD\n            , WillardMD, CardinetGHIII, et al.\n          Acquired myasthenia gravis. Selective involvement of esophageal, pharyngeal and facial muscles. J Vet Intern Med1990;4:2814."},{"key":"bib33","series-title":"Res Vet Sci","first-page":"249","article-title":"The neuropathic oesophagus. A radiographic and manometric study on the evolution of megaoesophagus in dogs with developing axonal neuropathy","volume":"48","author":"Satchell\n              P","year":"1990","unstructured":"Satchell\n              P\n            \n          . The neuropathic oesophagus. A radiographic and manometric study on the evolution of megaoesophagus in dogs with developing axonal neuropathy. Res Vet Sci1990;48:249\u201355."},{"key":"bib34","series-title":"Can Vet J","first-page":"66","article-title":"Idiopathic megaoesophagus in the dog: reasons for spontaneous improvement and a possible method of medical therapy","volume":"15","author":"Diamant\n              N","year":"1974","unstructured":"Diamant\n              N\n            , SzczepanskiM, MuiH. Idiopathic megaoesophagus in the dog: reasons for spontaneous improvement and a possible method of medical therapy. Can Vet J1974;15:66\u201371."},{"key":"bib35","series-title":"Am J Vet Res","first-page":"326","article-title":"Hereditary esophageal dysfunction in the Miniature Schnauzer dog","volume":"41","author":"Cox\n              VS","year":"1980","unstructured":"Cox\n              VS\n            , WallaceLJ, AndersonVE, et al.\n          Hereditary esophageal dysfunction in the Miniature Schnauzer dog. Am J Vet Res1980;41:326\u201330."},{"key":"bib36","series-title":"Vet Rec","first-page":"404","article-title":"Sildenafil improves clinical signs and radiographic features in dogs with congenital idiopathic megaesophagus: a randomized controlled trial","volume":"180","author":"Quintavalla\n              F","year":"2017","unstructured":"Quintavalla\n              F\n            , MenozziaA, PozzoliC, et al.\n          Sildenafil improves clinical signs and radiographic features in dogs with congenital idiopathic megaesophagus: a randomized controlled trial. Vet Rec2017;180:404."},{"key":"bib37","series-title":"J Am Vet Med Assoc","first-page":"1428","article-title":"Risk factors for acquired myasthenia gravis in dogs: 1154 cases (1991\u20131995)","volume":"211","author":"Shelton\n              GD","year":"1997","unstructured":"Shelton\n              GD\n            , SchuleA, KassPH. Risk factors for acquired myasthenia gravis in dogs: 1154 cases (1991\u20131995). J Am Vet Med Assoc1997;211:1428\u201331."},{"key":"bib38","series-title":"Vet Clin North Am Small Anim Pract","first-page":"31","article-title":"Electrophysiology in neuromuscular disease","volume":"32","author":"Cuddon, PA","year":"2002","unstructured":"Cuddon, PA\n          . Electrophysiology in neuromuscular disease. Vet Clin North Am Small Anim Pract2002;32:31\u201362."},{"key":"bib39","series-title":"J Vet Intern Med","first-page":"50","article-title":"Clinical forms of acquired myasthenia gravis in dogs: 25 cases (1988\u20131995)","volume":"11","author":"Dewey, C","year":"1997","unstructured":"Dewey, C, Bailey, C, Shelton, et al.\n          Clinical forms of acquired myasthenia gravis in dogs: 25 cases (1988\u20131995). J Vet Intern Med1997;11:50\u20137."},{"key":"bib40","series-title":"J Am Vet Med Assoc","first-page":"664","article-title":"Mycophenolate mofetil treatment in dogs with serologically diagnosed acquired myasthenia gravis: 27 cases (1999\u20132008)","volume":"236","author":"Dewey\n              C","year":"2010","unstructured":"Dewey\n              C\n            , Cerda-GonzalezS, FletcherD, et al.\n          Mycophenolate mofetil treatment in dogs with serologically diagnosed acquired myasthenia gravis: 27 cases (1999\u20132008). J Am Vet Med Assoc2010;236:664\u20138."},{"key":"bib41","series-title":"Neurology","first-page":"2139","article-title":"Spontaneous remission in canine myasthenia gravis: Implications for assessing human MG therapies","volume":"57","author":"Shelton\n              GD","year":"2001","unstructured":"Shelton\n              GD\n            , LindstromJM. Spontaneous remission in canine myasthenia gravis: Implications for assessing human MG therapies. Neurology2001;57:2139\u201341."},{"key":"bib42","series-title":"Vet Radiol Ultrasound","first-page":"108","article-title":"Radiographic findings of canine dysautonomia in twenty-four dogs","volume":"42","author":"Detweiler\n              DA","year":"2001","unstructured":"Detweiler\n              DA\n            , BillerDS, HoskinsonJJ, HarkinKR. Radiographic findings of canine dysautonomia in twenty-four dogs. Vet Radiol Ultrasound2001;42:108\u201312."},{"key":"bib43","series-title":"J Am Vet Med Assoc","first-page":"633","article-title":"Dysautonomia in dogs: 65 cases (1993\u20132000)","volume":"220","author":"Harkin\n              KR","year":"2002","unstructured":"Harkin\n              KR\n            , AndrewsGA, NietfeldJC. Dysautonomia in dogs: 65 cases (1993\u20132000). J Am Vet Med Assoc2002;220:633\u20139."},{"key":"bib44","series-title":"Vet Clin North Am Small Anim Pract","first-page":"251","article-title":"Dysautonomia and autonomic neuropathies","volume":"32","author":"O\u2019Brien\n              DP","year":"2002","unstructured":"O\u2019Brien\n              DP\n            , JohnsonGC. Dysautonomia and autonomic neuropathies. Vet Clin North Am Small Anim Pract2002;32:251\u201365."},{"key":"bib45","series-title":"Vet Clin North Am Small Anim Pract","first-page":"103","article-title":"Muscular dystrophies and other inherited myopathies","volume":"32","author":"Shelton\n              GD","year":"2002","unstructured":"Shelton\n              GD\n            , EngvallE. Muscular dystrophies and other inherited myopathies. Vet Clin North Am Small Anim Pract2002;32:103\u201324."},{"key":"bib46","series-title":"J Am Vet Med Assoc","first-page":"889","article-title":"Reversible megaoesophagus associated with atypical primary hypoadrenocorticism in a dog","volume":"201","author":"Bartges\n              JW","year":"1992","unstructured":"Bartges\n              JW\n            , NielsonDL. Reversible megaoesophagus associated with atypical primary hypoadrenocorticism in a dog. J Am Vet Med Assoc1992;201:889-91."},{"key":"bib47","series-title":"J Small Anim Pract","first-page":"1073","article-title":"Reversible mega-oesophagus in a dog with hypoadrenocorticism","volume":"28","author":"Burrows\n              C","year":"1987","unstructured":"Burrows\n              C\n            \n          . Reversible mega-oesophagus in a dog with hypoadrenocorticism. J Small Anim Pract1987;28:1073\u20138."},{"key":"bib48","series-title":"J Small Anim Pract","first-page":"132","article-title":"Megaooesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog","volume":"36","author":"Whitley\n              N","year":"1995","unstructured":"Whitley\n              N\n            \n          . Megaooesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog. J Small Anim Pract1995;36:132\u20135."},{"key":"bib49","series-title":"Vet Pathol","first-page":"1","article-title":"Malignant histiocytosis of Bernese mountain dogs","volume":"23","author":"Moore\n              P","year":"1986","unstructured":"Moore\n              P\n            , RosinA. Malignant histiocytosis of Bernese mountain dogs. Vet Pathol1986;23:1\u201310."}],"container-title":["Journal of the American Animal Hospital Association"],"original-title":[],"link":[{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/56\/1\/article-p7.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/jaaha\/article-pdf\/56\/1\/7\/2466452\/jaaha-ms-6955.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/56\/1\/article-p7.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/jaaha.kglmeridian.com\/downloadpdf\/journals\/aaha\/56\/1\/article-p7.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:03:38Z","timestamp":1763741018000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaaha.kglmeridian.com\/view\/journals\/aaha\/56\/1\/article-p7.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":49,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.5326\/jaaha-ms-6955","relation":{},"ISSN":["0587-2871","1547-3317"],"issn-type":[{"value":"0587-2871","type":"print"},{"value":"1547-3317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}