{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T16:17:53Z","timestamp":1763741873831,"version":"3.45.0"},"reference-count":10,"publisher":"American Animal Hospital Association","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>A 6 yr old spayed female Chihuahua was referred for a 10 mo history of chronic respiratory compromise. Decreased serum thyroxine and thyroid-stimulating hormone concentrations had been confirmed at a primary clinic, but no treatment was initiated. Serum biochemistries revealed elevated alkaline phosphatase and cholesterol concentrations. An adrenocorticotropic hormone\u2013stimulating test revealed elevated preserum and postserum cortisol concentrations. Fluoroscopy revealed marked epiglottic retroversion (ER) during inhalation. Enlarged bilateral adrenal glands were found on abdominal ultrasonography. Based on these findings, ER and hyperadrenocorticism (HAC) were diagnosed and surgical correction of the ER was planned. Trilostane administration was initiated before surgery to reduce the risk of thrombosis due to HAC. Seven days after the initiation of trilostane therapy, clinical signs of chronic respiratory compromise were resolved. The patient had remained clinically stable without recurrence of respiratory compromise for at least 15 mo at the time of this case report. This case suggests that HAC could contribute to the development of clinical signs of ER, which could potentially be successfully controlled by medical treatment of HAC.<\/jats:p>","DOI":"10.5326\/jaaha-ms-7225","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T14:15:59Z","timestamp":1667225759000},"page":"288-291","source":"Crossref","is-referenced-by-count":0,"title":["Resolution of Signs of Epiglottic Retroversion Following Medical Management of Hyperadrenocorticism in a Dog"],"prefix":"10.5326","volume":"58","author":[{"given":"Shota","family":"Wada","sequence":"first","affiliation":[{"name":"From Veterinary Teaching Hospital, University of Miyazaki, Miyazaki, Japan (S.W.)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kensuke","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Hokkaido University, Hokkaido, Japan (K.N.)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3280","reference":[{"key":"i1547-3317-58-6-288-b1","series-title":"J Am Vet Med Assoc","first-page":"1330","article-title":"Dyspnea caused by epiglottic retroversion in two dogs","volume":"235","year":"2009","unstructured":"Flanders\n              JA\n            \n            \n              Thompson\n              MS.\n            \n          \n          Dyspnea caused by epiglottic retroversion in two dogs.\n\t\t\t\t\tJ Am Vet Med Assoc2009;\n\t\t\t\t\t235:\n\t\t\t\t\t1330\u2013\n\t\t\t\t\t5."},{"key":"i1547-3317-58-6-288-b2","series-title":"J Vet Intern Med","first-page":"1611","article-title":"Clinical features and outcome of dogs with epiglottic retroversion with or without surgical treatment: 24 cases","volume":"29","year":"2015","unstructured":"Skerrett\n              SC,\n            \n            \n              Mcclaran\n              JK,\n            \n            \n              Fox\n              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