{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:12:13Z","timestamp":1758759133596,"version":"3.44.0"},"reference-count":80,"publisher":"Ubiquity Press, Ltd.","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TOHM"],"abstract":"<jats:p>Objectives: This review aims to provide a comprehensive understanding of Lance-Adams Syndrome (LAS), focusing on its pathophysiology, diagnosis, management, and patient outcomes.\nMethods: Utilizing the PICO framework, articles describing known cases of LAS and interventions were included, with no specific comparisons. The search was conducted in Google Scholar, PubMed, and Scopus databases.\nResults: LAS is characterized by action myoclonus and related symptoms. Imbalances in neurotransmitters and involvement of brain areas like the cerebellum, thalamus, and basal ganglia play a role in its pathophysiology. Diagnosis primarily relies on symptom history post-anoxic events, and treatments vary in effectiveness. LAS generally carries a more favorable functional prognosis than early post-anoxic status myoclonus, but often remains chronic and disabling.\nConclusion: LAS is a complex and rare neurological condition requiring early diagnosis and specific interventions. The compiled information provides a comprehensive overview, assisting clinicians in understanding and managing LAS. This review emphasizes the need for ongoing research and individualized patient care strategies, seeking to enhance overall patient quality of life.<\/jats:p>","DOI":"10.5334\/tohm.1074","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T11:31:29Z","timestamp":1758713489000},"page":"45","source":"Crossref","is-referenced-by-count":0,"title":["Lance-Adams Syndrome: An Updated Review of a Rare Post-Hypoxic 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