{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:23:41Z","timestamp":1783664621383,"version":"3.55.0"},"reference-count":37,"publisher":"Ubiquity Press, Ltd.","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01 NS086736"],"award-info":[{"award-number":["R01 NS086736"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TOHM"],"abstract":"<jats:p>Background: Evaluating tremor severity is a critical component of diagnosing and clinically managing patients with essential tremor (ET). We examined the comparability of tremor severity ratings derived from two frequently used tremor rating scales: the Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) rating scale and the Tremor Research Group Essential Tremor Rating Scale (TETRAS).\nMethods: A trained assistant administered and videotaped a neurological examination, including eight items assessing upper limb action tremor (arms outstretched, arms in the wingbeat position, finger-nose-finger maneuver, and drawing of Archimedes spirals). An experienced movement disorders neurologist reviewed the videos and assigned WHIGET and TETRAS ratings. We calculated associations between TETRAS and WHIGET ratings using Spearman rank order correlations. Subsequently, we collapsed these ratings into four tremor severity categories (absent, mild, moderate, severe) and then two broader tremor severity categories (absent\/mild, moderate\/severe). We calculated weighted Kappa coefficients to assess agreement between category assignments based on the TETRAS and the WHIGET.\nResults: Spearman\u2019s r\u2019 s were significant for all items (p\u2019s \u2264 0.001, mean r = 0.89). Weighted Kappa\u2019s revealed substantial to near perfect agreement for all eight items (mean k = 0.86, range = 0.64 to 1.00).\nConclusion: Analyses revealed substantial strength of association and substantial to near perfect agreement between items rated with the WHIGET and TETRAS scales. These data indicated that ratings provided by each scale are highly comparable.<\/jats:p>","DOI":"10.5334\/tohm.874","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T09:25:26Z","timestamp":1711531526000},"page":"14","source":"Crossref","is-referenced-by-count":8,"title":["WHIGET and TETRAS Ratings of Action Tremor in Patients with Essential Tremor: Substantial Association and Agreement"],"prefix":"10.5334","volume":"14","author":[{"given":"Adreanna B.","family":"Hernandez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4867-0663","authenticated-orcid":false,"given":"Diane S.","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Grill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal\u00eda M.","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Burkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8629-6599","authenticated-orcid":false,"given":"Ali","family":"Ghanem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5543-0305","authenticated-orcid":false,"given":"Vibhash D.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2062-362X","authenticated-orcid":false,"given":"Elan D.","family":"Louis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3285","published-online":{"date-parts":[[2024,3,27]]},"reference":[{"key":"key20240327092519_B1","first-page":"959","article-title":"Tremor. Contin. Minneap. Minn","volume":"25","year":"2019"},{"key":"key20240327092519_B2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/mds.10003","article-title":"Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study","volume":"17","year":"2002","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"},{"key":"key20240327092519_B3","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1468-1331.2012.03855.x","article-title":"The primary type of tremor in essential tremor is kinetic rather than postural: cross-sectional observation of tremor phenomenology in 369 cases","volume":"20","year":"2013","journal-title":"Eur. J. Neurol"},{"key":"key20240327092519_B4","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1001\/archneur.55.12.1553","article-title":"Is essential tremor symmetric? Observational data from a community-based study of essential tremor","volume":"55","year":"1998","journal-title":"Arch. Neurol"},{"key":"key20240327092519_B5","first-page":"51","article-title":"Postural and Intention Tremors: A Detailed Clinical Study of Essential Tremor vs. Parkinson\u2019s Disease","volume":"4","year":"2013","journal-title":"Front. Neurol"},{"key":"key20240327092519_B6","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1002\/mds.22370","article-title":"Intention tremor in essential tremor: Prevalence and association with disease duration","volume":"24","year":"2009","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"},{"key":"key20240327092519_B7","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1136\/jnnp.2010.229740","article-title":"Estimating annual rate of decline: prospective, longitudinal data on arm tremor severity in two groups of essential tremor cases","volume":"82","year":"2011","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"key20240327092519_B8","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/B978-0-323-98817-9.00012-0","article-title":"Essential tremor","volume":"196","year":"2023","journal-title":"Handb. Clin. Neurol"},{"key":"key20240327092519_B9","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1111\/ene.12123","article-title":"Essential tremor 10, 20, 30, 40: clinical snapshots of the disease by decade of duration","volume":"20","year":"2013","journal-title":"Eur. J. Neurol"},{"key":"key20240327092519_B10","first-page":"175","article-title":"Worse and Worse and Worse: Essential Tremor Patients\u2019 Longitudinal Perspectives on Their Condition","volume":"7","year":"2016","journal-title":"Front. Neurol"},{"key":"key20240327092519_B11","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1001\/archneur.55.6.823","article-title":"Diagnostic criteria for essential tremor: a population perspective","volume":"55","year":"1998","journal-title":"Arch. Neurol"},{"key":"key20240327092519_B12","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1159\/000109681","article-title":"The Washington Heights-Inwood Genetic Study of Essential Tremor: methodologic issues in essential-tremor research","volume":"16","year":"1997","journal-title":"Neuroepidemiology"},{"key":"key20240327092519_B13","doi-asserted-by":"crossref","first-page":"120202","DOI":"10.1016\/j.jns.2022.120202","article-title":"Tremor rating scales and laboratory tools for assessing tremor","volume":"435","year":"2022","journal-title":"J. Neurol. Sci"},{"key":"key20240327092519_B14","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/mds.870130215","article-title":"Reliability between two observers using a protocol for diagnosing essential tremor","volume":"13","year":"1998","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"},{"key":"key20240327092519_B15","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1001\/archneur.56.7.841","article-title":"Validity of a performance-based test of function in essential tremor","volume":"56","year":"1999","journal-title":"Arch. Neurol"},{"key":"key20240327092519_B16","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/WNF.0b013e3181ebd109","article-title":"A pilot efficacy and tolerability trial of memantine for essential tremor","volume":"33","year":"2010","journal-title":"Clin. Neuropharmacol"},{"key":"key20240327092519_B17","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1007\/s00415-005-0860-6","article-title":"Characterization of tremor in phenylketonuric patients","volume":"252","year":"2005","journal-title":"J. Neurol"},{"key":"key20240327092519_B18","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/lary.20702","article-title":"Clinical characteristics of essential voice tremor: A study of 34 cases","volume":"120","year":"2010","journal-title":"The Laryngoscope"},{"key":"key20240327092519_B19","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/00002826-200311000-00006","article-title":"Low Doses of Topiramate are Effective in Essential Tremor: A Report of Three Cases","volume":"26","year":"2003","journal-title":"Clin. Neuropharmacol"},{"key":"key20240327092519_B20","first-page":"tre-03\u2013192","article-title":"Prevalence of Essential Tremor on Arosa Island, Spain: a Community-based, Door-to-Door Survey","volume":"3","year":"2013","journal-title":"Tremor Hyperkinetic Mov. N. Y. N"},{"key":"key20240327092519_B21","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1212\/01.WNL.0000099075.19951.8C","article-title":"Prevalence of essential tremor: door-to-door neurologic exams in Mersin Province, Turkey","volume":"61","year":"2003","journal-title":"Neurology"},{"key":"key20240327092519_B22","doi-asserted-by":"crossref","first-page":"323","DOI":"10.5152\/TurkArchPediatr.2022.21218","article-title":"Prevalence of Potential Essential Tremor Cases in Turkish Adolescents According to The WHIGET Classification","volume":"57","year":"2022","journal-title":"Turk. Arch. Pediatr"},{"key":"key20240327092519_B23","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1080\/01616412.2019.1628409","article-title":"The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions","volume":"41","year":"2019","journal-title":"Neurol. Res"},{"key":"key20240327092519_B24","first-page":"100066","article-title":"Tremor analysis with wearable sensors correlates with outcome after thalamic deep brain stimulation","volume":"3","year":"2020","journal-title":"Clin. Park. Relat. Disord"},{"issue":"23","key":"key20240327092519_B25","first-page":"00144","article-title":"Voice Analysis in Patients with Essential Tremor","volume":"S0892\u20131997","year":"2023","journal-title":"J. Voice Off. J. Voice Found"},{"key":"key20240327092519_B26","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.parkreldis.2011.04.017","article-title":"Essential tremor quantification during activities of daily living","volume":"17","year":"2011","journal-title":"Parkinsonism Relat. Disord"},{"key":"key20240327092519_B27","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/mds.25162","article-title":"Reliability of a new scale for essential tremor","volume":"27","year":"2012","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"},{"key":"key20240327092519_B28","first-page":"35","article-title":"Transcranial focused ultrasound for the treatment of tremor: A preliminary case series","volume":"17","year":"2023","journal-title":"Brain Stimulat"},{"key":"key20240327092519_B29","doi-asserted-by":"crossref","first-page":"105850","DOI":"10.1016\/j.parkreldis.2023.105850","article-title":"Essential and dystonic head tremor: More similarities than differences","volume":"115","year":"2023","journal-title":"Parkinsonism Relat. Disord"},{"key":"key20240327092519_B30","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/jns.12528","article-title":"The effect of tremor on disability assessment in chronic inflammatory demyelinating polyradiculoneuropathy","volume":"28","year":"2023","journal-title":"J. Peripher. Nerv. Syst. JPNS"},{"key":"key20240327092519_B31","first-page":"36","article-title":"Tremor Research Group Essential Tremor Rating Scale (TETRAS): Assessing Impact of Different Item Instructions and Procedures","volume":"10","author":"Tremor Research Group","year":"2020","journal-title":"Tremor Hyperkinetic Mov. N. Y. N"},{"key":"key20240327092519_B32","doi-asserted-by":"crossref","first-page":"120854","DOI":"10.1016\/j.jns.2023.120854","article-title":"A prospective cohort study of familial versus sporadic essential tremor cases: Do clinical features evolve differently across time?","volume":"454","year":"2023","journal-title":"J. Neurol. Sci"},{"key":"key20240327092519_B33","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.parkreldis.2022.07.018","article-title":"Distribution of rest tremor in patients with Essential Tremor: Does it lateralize with simple kinetic, postural, or intention tremors?","volume":"102","year":"2022","journal-title":"Parkinsonism Relat. Disord"},{"key":"key20240327092519_B34","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/mds.27121","article-title":"Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society","volume":"33","year":"2018","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"},{"key":"key20240327092519_B35","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1037\/h0026256","article-title":"Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit","volume":"70","year":"1968","journal-title":"Psychol. Bull"},{"key":"key20240327092519_B36","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","year":"1977","journal-title":"Biometrics"},{"key":"key20240327092519_B37","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/mds.21412","article-title":"Assessment of interrater and intrarater reliability of the Fahn-Tolosa-Marin Tremor Rating Scale in essential tremor","volume":"22","year":"2007","journal-title":"Mov. Disord. Off. J. Mov. Disord. Soc"}],"container-title":["Tremor and Other Hyperkinetic Movements"],"original-title":[],"link":[{"URL":"https:\/\/account.tremorjournal.org\/index.php\/up-j-tohm\/article\/download\/874\/1825","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/account.tremorjournal.org\/index.php\/up-j-tohm\/article\/download\/874\/1826","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/account.tremorjournal.org\/index.php\/up-j-tohm\/article\/download\/874\/1827","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/account.tremorjournal.org\/index.php\/up-j-tohm\/article\/download\/874\/1825","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T10:45:16Z","timestamp":1782816316000},"score":1,"resource":{"primary":{"URL":"https:\/\/account.tremorjournal.org\/index.php\/up-j-tohm\/article\/view\/874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,27]]},"references-count":37,"URL":"https:\/\/doi.org\/10.5334\/tohm.874","relation":{},"ISSN":["2160-8288"],"issn-type":[{"value":"2160-8288","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,27]]}}}