{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:55:46Z","timestamp":1777312546631,"version":"3.51.4"},"reference-count":28,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,14]]},"abstract":"<jats:p>Adenosine is frequently used for paroxysmal supraventricular tachycardia (PSVT) treatment in the emergency department (ED). Atrial and ventricular pro-arrhythmic effects of adenosine were described in the literature, but ventricular fibrillation (VF) secondary to adenosine administration was rarely reported (with an incidence of &lt;\u00a01%). Reported herein is the first case of a 72-year-old female patient who developed VF hemodynamic collapse after an intravenous administration of adenosine for PSVT treatment. She had no known pre-excitation or accessory pathway, nor any underlying structural heart disease or prolonged QT syndrome. Raising awareness of this potential life-threatening pro-arrhythmic effect of adenosine is important, given its frequent use for PSVT treatment in the ED.<\/jats:p>","DOI":"10.5339\/qmj.2021.52","type":"journal-article","created":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T10:30:49Z","timestamp":1637922649000},"source":"Crossref","is-referenced-by-count":3,"title":["Adenosine-induced ventricular fibrillation in a patient with supraventricular tachycardia"],"prefix":"10.5339","volume":"2021","author":[{"given":"Shu Yu","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Woodlands Health Campus, National Healthcare Group, Singapore E-mail: shu_yu_lee@whc.sg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohil","family":"Pothiawala","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Woodlands Health Campus, National Healthcare Group, Singapore E-mail: shu_yu_lee@whc.sg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong","family":"Meng Seet","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Sengkang General Hospital, Singhealth Services, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3277","reference":[{"issue":"(2):","key":"CIT0001","series-title":"Qatar Med J","first-page":"33","article-title":"Prehospital conversion of paroxysmal supraventricular tachycardia using the modified Valsalva maneuver: a case report","volume":"34;","year":"2020"},{"issue":"(12):","key":"CIT0002","series-title":"Circ Arrhythm Electrophysiol","first-page":"e006953","article-title":"Supraventricular tachycardia: mechanistic insights deduced from adenosine","volume":"11","year":"2018;"},{"issue":"(13):","key":"CIT0003","series-title":"J Am Coll Cardiol","first-page":"e27\u2013e115","article-title":"2015 ACC\/AHA\/HRS Guideline for the management of adult patients with supraventricular tachycardia: a report of the American college of cardiology\/American heart association task force on clinical practice guidelines and the Heart Rhythm Society","volume":"67","year":"2016;"},{"issue":"(1):","key":"CIT0004","series-title":"Indian Pacing Electrophysiol J","first-page":"36-38","article-title":"An unusual complication of adenosine administration in supraventricular tachycardia","volume":"18","year":"2018;"},{"issue":"(4):","key":"CIT0005","series-title":"Circulation","first-page":"1192\u2013200","article-title":"Adenosine-sensitive ventricular tachycardia: right ventricular abnormalities delineated by magnetic resonance imaging","volume":"96","year":"1997;"},{"issue":"(1):","key":"CIT0006","series-title":"Pacing Clin Electrophysiol","first-page":"140\u2013141","article-title":"Adenosine induced atrial fibrillation precipitating polymorphic ventricular tachycardia","volume":"23","year":"2000;"},{"issue":"(4):","key":"CIT0007","series-title":"J Cardiovasc Electrophysiol","first-page":"491\u2013492","article-title":"Adenosine-induced tachycardia: what is the mechanism","volume":"11","year":"2000;"},{"issue":"(4):","key":"CIT0008","series-title":"Ann Noninvasive Electrocardiol","first-page":"386\u2013390","article-title":"Adenosine-induced ventricular arrhythmias in patients with supraventricular tachycardias","volume":"13","year":"2008;"},{"issue":"(2):","key":"CIT0009","series-title":"J Electrocardiol","first-page":"171\u2013173","article-title":"Torsades de pointes after adenosine administration","volume":"49","year":"2016;"},{"issue":"(1):","key":"CIT0010","series-title":"J Med Case Rep","first-page":"21","article-title":"Adenosine induced ventricular fibrillation in a structurally normal heart: a case report","volume":"11","year":"2017;"},{"issue":"(4):","key":"CIT0011","series-title":"Emerg Med J","first-page":"408\u2013410","article-title":"Proarrhythmic effects of adenosine: a review of the literature","volume":"21","year":"2004;"},{"issue":"(23):","key":"CIT0012","series-title":"Arch Intern Med","first-page":"2701\u20132702","article-title":"Ventricular fibrillation following adenosine administration. A case report","volume":"153","year":"1993;"},{"issue":"(3):","key":"CIT0013","series-title":"Am Heart J","first-page":"794\u2013796","article-title":"Torsades de pointe after intravenous adenosine in the presence of prolonged QT syndrome","volume":"123","year":"1992;"},{"issue":"(5):","key":"CIT0014","series-title":"Circulation","first-page":"1668\u20131675","article-title":"Adenosine increases sympathetic nerve traffic in humans","volume":"83","year":"1991;"},{"issue":"(2):","key":"CIT0001","series-title":"Qatar Med J","first-page":"33","article-title":"Prehospital conversion of paroxysmal supraventricular tachycardia using the modified Valsalva maneuver: a case report","volume":"34;","year":"2020"},{"issue":"(12):","key":"CIT0002","series-title":"Circ Arrhythm Electrophysiol","first-page":"e006953","article-title":"Supraventricular tachycardia: mechanistic insights deduced from adenosine","volume":"11","year":"2018;"},{"issue":"(13):","key":"CIT0003","series-title":"J Am Coll Cardiol","first-page":"e27\u2013e115","article-title":"2015 ACC\/AHA\/HRS Guideline for the management of adult patients with supraventricular tachycardia: a report of the American college of cardiology\/American heart association task force on clinical practice guidelines and the Heart Rhythm Society","volume":"67","year":"2016;"},{"issue":"(1):","key":"CIT0004","series-title":"Indian Pacing Electrophysiol J","first-page":"36-38","article-title":"An unusual complication of adenosine administration in supraventricular tachycardia","volume":"18","year":"2018;"},{"issue":"(4):","key":"CIT0005","series-title":"Circulation","first-page":"1192\u2013200","article-title":"Adenosine-sensitive ventricular tachycardia: right ventricular abnormalities delineated by magnetic resonance imaging","volume":"96","year":"1997;"},{"issue":"(1):","key":"CIT0006","series-title":"Pacing Clin Electrophysiol","first-page":"140\u2013141","article-title":"Adenosine induced atrial fibrillation precipitating polymorphic ventricular tachycardia","volume":"23","year":"2000;"},{"issue":"(4):","key":"CIT0007","series-title":"J Cardiovasc Electrophysiol","first-page":"491\u2013492","article-title":"Adenosine-induced tachycardia: what is the mechanism","volume":"11","year":"2000;"},{"issue":"(4):","key":"CIT0008","series-title":"Ann Noninvasive Electrocardiol","first-page":"386\u2013390","article-title":"Adenosine-induced ventricular arrhythmias in patients with supraventricular tachycardias","volume":"13","year":"2008;"},{"issue":"(2):","key":"CIT0009","series-title":"J Electrocardiol","first-page":"171\u2013173","article-title":"Torsades de pointes after adenosine administration","volume":"49","year":"2016;"},{"issue":"(1):","key":"CIT0010","series-title":"J Med Case Rep","first-page":"21","article-title":"Adenosine induced ventricular fibrillation in a structurally normal heart: a case report","volume":"11","year":"2017;"},{"issue":"(4):","key":"CIT0011","series-title":"Emerg Med J","first-page":"408\u2013410","article-title":"Proarrhythmic effects of adenosine: a review of the literature","volume":"21","year":"2004;"},{"issue":"(23):","key":"CIT0012","series-title":"Arch Intern Med","first-page":"2701\u20132702","article-title":"Ventricular fibrillation following adenosine administration. A case report","volume":"153","year":"1993;"},{"issue":"(3):","key":"CIT0013","series-title":"Am Heart J","first-page":"794\u2013796","article-title":"Torsades de pointe after intravenous adenosine in the presence of prolonged QT syndrome","volume":"123","year":"1992;"},{"issue":"(5):","key":"CIT0014","series-title":"Circulation","first-page":"1668\u20131675","article-title":"Adenosine increases sympathetic nerve traffic in humans","volume":"83","year":"1991;"}],"container-title":["Qatar Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2021\/3\/article-52.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2021\/3\/article-52.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2021\/3\/article-52.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:20:57Z","timestamp":1777310457000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2021\/3\/article-52.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,14]]},"references-count":28,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.5339\/qmj.2021.52","relation":{},"ISSN":["2227-0426"],"issn-type":[{"value":"2227-0426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,14]]}}}