{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:53:46Z","timestamp":1777312426558,"version":"3.51.4"},"reference-count":36,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"abstract":"\n Background:<\/jats:bold>\n Diabetic striatopathy (DS) typically presents with hemichoreoballism and contralateral striatal lesions on neuroimaging. However, cases of unilateral movement disorders with predominant ipsilateral striatal lesions are rare.\n <\/jats:p>\n \n Case presentation:<\/jats:bold>\n We present a case of DS in a 62-year-old woman from rural India with poorly controlled diabetes mellitus who developed acute-onset right hemichoreoballism. Neuroimaging revealed a predominantly right-sided striatal lesion, illustrating a clinicoradiological discordance\u2014a mismatch between the clinical symptoms and radiological findings. Despite achieving tight glycemic control and administering neuroleptic medications, the involuntary movements demonstrated only partial improvement. Neurological changes persisted on the ipsilateral side of the affected limbs even after 1 year of follow-up. Notably, perioral dyskinesias developed during subsequent follow-up visits.\n <\/jats:p>\n \n Discussion:<\/jats:bold>\n This report highlights the clinical and neuroradiological discordance observed in DS. The potential underlying mechanisms contributing to this paradox are explored and discussed.\n <\/jats:p>\n \n Conclusion:<\/jats:bold>\n The clinical and radiological discordance in DS is a frequent yet under-reported phenomenon. However, the actual mechanistic underpinnings need to be addressed by advanced functional and structural neuroimaging.\n <\/jats:p>","DOI":"10.5339\/qmj.2025.60","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T06:30:48Z","timestamp":1750141848000},"source":"Crossref","is-referenced-by-count":0,"title":["Ipsilateral diabetic striatopathy: A case of clinicoradiological discordance and evolving movement disorders"],"prefix":"10.5339","volume":"2025","author":[{"given":"Subhankar","family":"Chatterjee","sequence":"first","affiliation":[{"name":"Department of Endocrinology & Metabolism, Medical College & Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payel","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Radiology, GNRC Hospital, Barasat, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samya","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine, Bangur Institute of Neurosciences, IPGMER & SSKM Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shambaditya","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine, Bangur Institute of Neurosciences, IPGMER & SSKM Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritwik","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Burdwan Medical College &Hospital, Burdwan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rana","family":"Bhattacharjee","sequence":"additional","affiliation":[{"name":"Department of Endocrinology & Metabolism, Medical College & Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juli\u00e1n","family":"Benito-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Neurology, 12 de Octubre University Hospital, Madrid, Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain"},{"name":"Department of Medicine, Faculty of Medicine, Complutense University, Madrid, Spain*Correspondence: Julian Benito-Leon jbenitol67@gmail.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souvik","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine, Bangur Institute of Neurosciences, IPGMER & SSKM Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3277","reference":[{"key":"CIT0001","series-title":"Diabetes Metab Syndr","first-page":"102997","article-title":"Diabetic striatopathy and other acute onset de novo movement disorders in hyperglycemia","volume":"18","author":"Chatterjee\n \nS","year":"2024;"},{"key":"CIT0002","series-title":"Sci Rep","first-page":"1594","article-title":"\u201cDiabetic striatopathy\u201d: clinical presentations, controversy, pathogenesis, treatments, and outcomes","volume":"10","author":"Chua\n \nCB","year":"2020;"},{"key":"CIT0003","series-title":"Tremor Other Hyperkinet Mov (N Y)","first-page":"50","article-title":"Expanding the spectrum of diabetic striatopathy: insights from a case of hyperglycemia-induced propriospinal myoclonus","volume":"13","author":"Mukherjee\n \nD","year":"2023;"},{"key":"CIT0004","series-title":"Eur J Neurol","first-page":"2241\u20138","article-title":"Acute onset movement disorders in diabetes mellitus: a clinical series of 59 patients","volume":"29","author":"Dubey\n \nS","year":"2022;"},{"key":"CIT0005","series-title":"Eur Neurol","first-page":"371\u20136","article-title":"Neuroimaging of diabetic striatopathy: more questions than answers","volume":"85","author":"Dubey\n \nS","year":"2022;"},{"key":"CIT0006","series-title":"In:","article-title":"Diabetic striatopathy","author":"Chatterjee\n \nS","year":"2000"},{"key":"CIT0007","series-title":"Parkinsonism Relat Disord","first-page":"319\u201321","article-title":"Ipsilateral putamen hyperintensity on T1-weighted MRI in non-ketotic hyperglycemia with hemiballism-hemichorea: a case report","volume":"7","author":"Lin\n \nJJ","year":"2001;"},{"key":"CIT0008","series-title":"J Mov Disord","first-page":"187\u20139","article-title":"Hyperglycemia-associated hemichorea-hemiballismus with predominant ipsilateral putaminal abnormality on neuroimaging","volume":"12","author":"Fong\n \nSL","year":"2019;"},{"key":"CIT0009","series-title":"Neurology","first-page":"e480\u20131","article-title":"Teaching neuroimages: stroke with nondecussating corticospinal tracts causing ipsilateral weakness: straight forward","volume":"96","author":"Zhou\n \nLW","year":"2021;"},{"key":"CIT0010","series-title":"Tremor Other Hyperkinet Mov (N Y)","first-page":"359","article-title":"Ipsilateral hemichorea-hemiballism in a case of postoperative stroke","volume":"6","author":"Kannepalli\n \nNR","year":"2016;"},{"key":"CIT0011","series-title":"Exp Neurol","first-page":"1\u20135","article-title":"Are two leads always better than one: an emerging case for unilateral subthalamic deep brain stimulation in Parkinson\u2019s disease","volume":"214","author":"Alberts\n \nJL","year":"2008;"},{"key":"CIT0012","series-title":"J Neurosurg","first-page":"216\u201322","article-title":"Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor","volume":"102","author":"Slevin\n \nJT","year":"2005;"},{"key":"CIT0013","series-title":"Parkinsonism Relat 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