{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T19:33:15Z","timestamp":1789759995969,"version":"4.0.1"},"reference-count":72,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"abstract":"\n Introduction:<\/jats:bold>\n Reproductive technologies are used more widely today than ever before. This increase in the use of assisted reproductive technology (ART) is directly related to sociodemographic conditions that result in delayed childbirth among age groups with lower fertility. Infertility affects 17% of married couples, and in some countries 6% of children are born with in vitro fertilization (IVF). In this context, the aspect of the influence of reproductive technologies on hormonal indicators of offspring in relation to anthropometric data remains insufficiently examined. The purpose of this cohort study is to compare the hormonal panel and anthropometric data of ART-conceived children with the corresponding data of children conceived naturally.\n <\/jats:p>\n \n Methodology:<\/jats:bold>\n Biochemical tests are used to determine the amount of free triiodothyronine (T3) and total thyroxine (T4), somatotropin, insulin, insulin-like growth factor, glucose, potassium, and sodium cations in blood samples from the experimental and control groups.\n <\/jats:p>\n \n Results:<\/jats:bold>\n The results indicate that the use of assisted reproductive technologies neither altered the endocrine panel of the thyroid gland, nor affected other biochemical parameters. Variations in technologies \u2013 classical IVF, fresh or frozen embryo transfer, intracytoplasmic sperm injection \u2013 also did not affect the quantitative value of the above indicators. Artificial insemination also had no effect on puberty (in both boys and girls). Children born naturally had a greater body weight (3,453 vs 3,160 g,\n p<\/jats:italic>\n \u00a0<\u00a00.001) and height (53 vs 51 cm,\n p<\/jats:italic>\n \u00a0=\u00a00.002). ART children had significantly higher median free T3 levels (3.65 vs 3.48 mU\/L,\n p<\/jats:italic>\n \u00a0=\u00a00.002) and potassium levels (4.8 vs 4.7 mmol\/L,\n p<\/jats:italic>\n \u00a0=\u00a00.013), although within the reference ranges. Glucose levels were also higher in ART children (median 4.45 vs 4.29 mg\/dl,\n p<\/jats:italic>\n \u00a0=\u00a00.01).\n <\/jats:p>\n \n Conclusion:<\/jats:bold>\n Several relationships between biochemical and anthropometric indicators were identified: the correlation between body weight and blood levels of insulin-like growth factor was statistically significant, positive, and weak. The T3 level in the experimental group was found to be statistically significant and directly proportional to body height, and insulin content was inversely proportional to body weight. The data obtained make it possible to verify the safety of using a different range of reproductive technologies.\n <\/jats:p>","DOI":"10.5339\/qmj.2025.9","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T03:30:26Z","timestamp":1745206226000},"source":"Crossref","is-referenced-by-count":1,"title":["Focus on the endocrine system of children born after reproductive technologies in Kazakhstan"],"prefix":"10.5339","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5445-8293","authenticated-orcid":true,"given":"Sevara","family":"Ilmuratova","sequence":"first","affiliation":[{"name":"Department of Science and Consulting, Kazakhstan Medical University KSPH, Almaty, Republic of Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8775-3985","authenticated-orcid":true,"given":"Lyazzat","family":"Manzhuova","sequence":"additional","affiliation":[{"name":"Department of Science and Postgraduate Education, Scientific Center of Pediatrics and Children's Surgery, Almaty, Republic of Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5564-2914","authenticated-orcid":true,"given":"Aigul","family":"Bazarbayeva","sequence":"additional","affiliation":[{"name":"Department of Science and Postgraduate Education, Scientific Center of Pediatrics and Children's Surgery, Almaty, Republic of Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4792-5380","authenticated-orcid":true,"given":"Vyacheslav","family":"Lokshin","sequence":"additional","affiliation":[{"name":"Department of Assisted Reproductive Technologies, International Clinical Center for Reproductology PERSONA, Almaty, Republic of Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0490-8000","authenticated-orcid":true,"given":"Zhanar","family":"Nurgaliyeva","sequence":"additional","affiliation":[{"name":"Department of Childhood Diseases named after Professor N.A. Barlybaeva, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farida","family":"Kussainova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Asfendiyarov Kazakh National Medical University, Almaty, Republic of Kazakhstan*Correspondence: Aigul Bazarbayeva. Email: aigu.bazarbayeva@gmail.com"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3277","reference":[{"issue":"11:","key":"CIT0001","series-title":"Obstet Gynecol","first-page":"5\u201310","article-title":"Management strategies for thrombophilic patients undergoing assisted reproductive technologies","author":"Isenova\n \nSSh\n,","year":"2023;"},{"issue":"(2):","key":"CIT0002","series-title":"Int J Epidemiol","first-page":"365\u2013366f","article-title":"Data resource profile: Committee of Nordic Assisted Reproductive Technology and Safety (CoNARTaS) cohort","volume":"49","author":"Opdahl\n \nS\n,","year":"2020"},{"key":"CIT0003"},{"issue":"3:","key":"CIT0004","series-title":"Hum Reprod Open","first-page":"hoaa032","year":"2021"},{"key":"CIT0005","article-title":"Practical reproductology","author":"Lokshin\n \nVN"},{"issue":"11:","key":"CIT0006","series-title":"Obstet Gynecol","first-page":"31\u201336","article-title":"Cognitive development and neuropsychic health of children conceived by assisted reproductive technologies","author":"Lokshin\n \nVN\n,","year":"2022"},{"issue":"12:","key":"CIT0007","series-title":"BMC Med","first-page":"240","article-title":"Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of pregnancy: a cross-sectional study","author":"Lv\n \nP-P\n,","year":"2014"},{"issue":"(6):","key":"CIT0008","series-title":"J Assist Reprod Genet","first-page":"1267\u20131272","article-title":"Impact of contraception and IVF hormones on metabolic, endocrine, and inflammatory status","volume":"37","author":"Coussa\n \nA\n,","year":"2020"},{"issue":"(1):","key":"CIT0009","series-title":"J Dev Orig Health Dis","first-page":"73\u201382","article-title":"Adult male mice conceived by in vitro fertilization exhibit increased glucocorticoid receptor expression in fat tissue","volume":"7","author":"Simbulan\n \nRK\n,","year":"2016"},{"issue":"25:","key":"CIT0010","series-title":"Middle East Fertil Soc J","first-page":"6","article-title":"Assisted reproductive technology and the risk of gestational diabetes mellitus: a systematic review and meta-analysis","author":"Mohammadi\n \nM\n,","year":"2020"},{"issue":"(4):","key":"CIT0011","series-title":"Hum Reprod Update","first-page":"514\u2013544","article-title":"Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis","volume":"26","author":"Bosdou\n \nJK\n,","year":"2020"},{"issue":"(8):","key":"CIT0012","series-title":"Hum Reprod","first-page":"1548\u20131556","article-title":"Severe maternal morbidity in women with high BMI in IVF and unassisted singleton pregnancies","volume":"33","author":"Dayan\n \nN\n,","year":"2018"},{"issue":"(2):","key":"CIT0013","series-title":"Reprod Biomed Online","first-page":"162\u2013182","article-title":"Health outcomes of children born after IVF\/ICSI: a review of current expert opinion and literature","volume":"28","author":"Fauser\n \nBCJM\n,","year":"2014"},{"issue":"(3):","key":"CIT0014","series-title":"Fertil Steril","first-page":"622\u2013631.e5","article-title":"Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis","volume":"107","author":"Guo\n \nX-Y\n,","year":"2017"},{"issue":"(1):","key":"CIT0015","series-title":"Hum Reprod Open","first-page":"hoz037","article-title":"Increased blood pressure and impaired endothelial function after accelerated growth in IVF\/ICSI children","volume":"2020","author":"Zandstra\n \nH\n,","year":"2020"},{"issue":"(10):","key":"CIT0016","series-title":"Diabetologia","first-page":"2150\u20132157","article-title":"Increased risk of metabolic dysfunction in children conceived by assisted reproductive technology","volume":"63","author":"Cui\n \nL\n,","year":"2020"},{"issue":"(9):","key":"CIT0017","series-title":"PLoS Med","first-page":"e1003723","article-title":"Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: a population-based cohort study","volume":"18","author":"Norrman\n \nE\n,","year":"2021"},{"issue":"(2):","key":"CIT0018","series-title":"Fertil Steril","first-page":"349\u2013359","article-title":"Conception by fertility treatment and cardiometabolic risk in middle childhood","volume":"118","author":"Yeung\n \nEH\n,","year":"2022"},{"issue":"148:","key":"CIT0019","series-title":"Early Hum Dev","first-page":"105132","article-title":"Long-term endocrine disorders in children born from pregnancies conceived following fertility treatments","author":"Steiner\n \nN\n,","year":"2020"},{"issue":"2018:","key":"CIT0020","series-title":"Int J Endocrinol","first-page":"8170518","article-title":"Metabolic syndrome and its components in young adults conceived by ICSI","author":"Belva\n \nF\n,","year":"2018"},{"issue":"(1):","key":"CIT0021","series-title":"Hum Reprod","first-page":"232\u2013239","article-title":"American Heart Association ideal cardiovascular health score and subclinical atherosclerosis in 22-35-year-old adults conceived with and without assisted reproductive technologies","volume":"35","author":"Juonala\n \nM\n,","year":"2020"},{"issue":"(7):","key":"CIT0022","series-title":"PLoS One","first-page":"e0272064","article-title":"Cohort profile: the Growing Up Healthy Study (GUHS) \u2013 a prospective and observational cohort study investigating the long-term health outcomes of offspring conceived after assisted reproductive technologies","volume":"17","author":"Penova-Veselinovic\n \nB\n,","year":"2022"},{"key":"CIT0023","series-title":"WHO Child Growth Standards. Growth velocity based on weight, length and head circumference: methods and development","year":"2009"},{"issue":"(9):","key":"CIT0024","series-title":"J Clin Endocrinol Metab","first-page":"3441\u20133445","article-title":"In vitro fertilization improves childhood growth and metabolism","volume":"92","author":"Miles\n \nHL\n,","year":"2007"},{"issue":"(1):","key":"CIT0025","series-title":"Reprod Med Biol","first-page":"e12506","article-title":"Anthropometric measurements of term singletons at 6 years of age born from fresh and frozen embryo transfer: A multicenter prospective study in Japan","volume":"22","author":"Ueno\n \nK\n,","year":"2023"},{"issue":"(3):","key":"CIT0026","series-title":"Reprod Sci","first-page":"583\u2013590","article-title":"The long-term outcome of children conceived through assisted reproductive technology","volume":"31","author":"Ono\n \nM\n,","year":"2024"},{"issue":"(12):","key":"CIT0027","series-title":"PLoS Med","first-page":"e1004324","article-title":"Overweight or obesity in children born after assisted reproductive technologies in Denmark: a population-based cohort study","volume":"20","author":"Laugesen\n \nK\n,","year":"2023"},{"issue":"(6):","key":"CIT0028","series-title":"PLoS Med","first-page":"e1002817","article-title":"The association between maternal body mass index and child obesity: a systematic review and meta-analysis","volume":"16","author":"Heslehurst\n \nN\n,","year":"2019"},{"issue":"(4):","key":"CIT0029","series-title":"Bull Med Biol Res","first-page":"34\u201341","article-title":"Microbiological diagnostics: from traditional to molecular genetic methods: a literature review","volume":"5","author":"Ivashko\n \nM\n,","year":"2023"},{"issue":"(8):","key":"CIT0030","series-title":"Birth Defects Res","first-page":"630\u2013643","article-title":"Large for gestational age and macrosomia in singletons born after frozen\/thawed embryo transfer (FET) in assisted reproductive technology (ART)","volume":"110","author":"Berntsen\n \nS\n,","year":"2018"},{"issue":"(2):","key":"CIT0031","series-title":"Reprod Biomed Online","first-page":"300\u2013308","article-title":"Maternal and perinatal outcomes in programmed versus natural vitrified-warmed blastocyst transfer cycles","volume":"41","author":"Makhijani\n \nR\n,","year":"2020"},{"issue":"(2):","key":"CIT0032","series-title":"Am J Obstet Gynecol","first-page":"126.e1\u2013126.e18","article-title":"Neonatal and maternal outcome after frozen embryo transfer: Increased risks in programmed cycles","volume":"221","author":"Ernstad\n \nEG\n,","year":"2019"},{"issue":"(1):","key":"CIT0033","series-title":"J Pediatr Urol","first-page":"9\u201320","article-title":"Assisted reproductive technologies and the risk of congenital urogenital tract malformations: A systematic review and meta-analysis","volume":"17","author":"Zhang\n \nZ\n,","year":"2021"},{"issue":"(5\u00a0Suppl.):","key":"CIT0034","series-title":"J Urol","first-page":"1837\u20131842","article-title":"Does intracytoplasmic sperm injection pose an increased risk of genitourinary congenital malformations in offspring compared to in vitro fertilization? A systematic review and meta-analysis","volume":"193","author":"Massaro\n \nPA\n,","year":"2015"},{"issue":"(12):","key":"CIT0035","series-title":"Hum Reprod","first-page":"2811\u20132820","article-title":"Semen quality of young adult ICSI offspring: The first results","volume":"31","author":"Belva\n \nF\n,","year":"2016"},{"issue":"(1):","key":"CIT0036","series-title":"Bull Med Biol Res","first-page":"10\u201314","article-title":"Features of the blood supply of some areas of the head in human fetuses","volume":"5","author":"Komar\n \nTV\n,","year":"2023;"},{"issue":"11:","key":"CIT0001","series-title":"Obstet Gynecol","first-page":"5\u201310","article-title":"Management strategies for thrombophilic patients undergoing assisted reproductive technologies","author":"Isenova\n \nSSh\n,","year":"2023;"},{"issue":"(2):","key":"CIT0002","series-title":"Int J Epidemiol","first-page":"365\u2013366f","article-title":"Data resource profile: Committee of Nordic Assisted Reproductive Technology and Safety (CoNARTaS) cohort","volume":"49","author":"Opdahl\n \nS\n,","year":"2020"},{"key":"CIT0003"},{"issue":"3:","key":"CIT0004","series-title":"Hum Reprod Open","first-page":"hoaa032","year":"2021"},{"key":"CIT0005","article-title":"Practical reproductology","author":"Lokshin\n \nVN"},{"issue":"11:","key":"CIT0006","series-title":"Obstet Gynecol","first-page":"31\u201336","article-title":"Cognitive development and neuropsychic health of children conceived by assisted reproductive technologies","author":"Lokshin\n \nVN\n,","year":"2022"},{"issue":"12:","key":"CIT0007","series-title":"BMC Med","first-page":"240","article-title":"Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of pregnancy: a cross-sectional study","author":"Lv\n \nP-P\n,","year":"2014"},{"issue":"(6):","key":"CIT0008","series-title":"J Assist Reprod Genet","first-page":"1267\u20131272","article-title":"Impact of contraception and IVF hormones on metabolic, endocrine, and inflammatory status","volume":"37","author":"Coussa\n \nA\n,","year":"2020"},{"issue":"(1):","key":"CIT0009","series-title":"J Dev Orig Health Dis","first-page":"73\u201382","article-title":"Adult male mice conceived by in vitro fertilization exhibit increased glucocorticoid receptor expression in fat tissue","volume":"7","author":"Simbulan\n \nRK\n,","year":"2016"},{"issue":"25:","key":"CIT0010","series-title":"Middle East Fertil Soc J","first-page":"6","article-title":"Assisted reproductive technology and the risk of gestational diabetes mellitus: a systematic review and meta-analysis","author":"Mohammadi\n \nM\n,","year":"2020"},{"issue":"(4):","key":"CIT0011","series-title":"Hum Reprod Update","first-page":"514\u2013544","article-title":"Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis","volume":"26","author":"Bosdou\n \nJK\n,","year":"2020"},{"issue":"(8):","key":"CIT0012","series-title":"Hum Reprod","first-page":"1548\u20131556","article-title":"Severe maternal morbidity in women with high BMI in IVF and unassisted singleton pregnancies","volume":"33","author":"Dayan\n \nN\n,","year":"2018"},{"issue":"(2):","key":"CIT0013","series-title":"Reprod Biomed Online","first-page":"162\u2013182","article-title":"Health outcomes of children born after IVF\/ICSI: a review of current expert opinion and literature","volume":"28","author":"Fauser\n \nBCJM\n,","year":"2014"},{"issue":"(3):","key":"CIT0014","series-title":"Fertil Steril","first-page":"622\u2013631.e5","article-title":"Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis","volume":"107","author":"Guo\n \nX-Y\n,","year":"2017"},{"issue":"(1):","key":"CIT0015","series-title":"Hum Reprod Open","first-page":"hoz037","article-title":"Increased blood pressure and impaired endothelial function after accelerated growth in IVF\/ICSI children","volume":"2020","author":"Zandstra\n \nH\n,","year":"2020"},{"issue":"(10):","key":"CIT0016","series-title":"Diabetologia","first-page":"2150\u20132157","article-title":"Increased risk of metabolic dysfunction in children conceived by assisted reproductive technology","volume":"63","author":"Cui\n \nL\n,","year":"2020"},{"issue":"(9):","key":"CIT0017","series-title":"PLoS Med","first-page":"e1003723","article-title":"Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: a population-based cohort study","volume":"18","author":"Norrman\n \nE\n,","year":"2021"},{"issue":"(2):","key":"CIT0018","series-title":"Fertil Steril","first-page":"349\u2013359","article-title":"Conception by fertility treatment and cardiometabolic risk in middle childhood","volume":"118","author":"Yeung\n \nEH\n,","year":"2022"},{"issue":"148:","key":"CIT0019","series-title":"Early Hum Dev","first-page":"105132","article-title":"Long-term endocrine disorders in children born from pregnancies conceived following fertility treatments","author":"Steiner\n \nN\n,","year":"2020"},{"issue":"2018:","key":"CIT0020","series-title":"Int J Endocrinol","first-page":"8170518","article-title":"Metabolic syndrome and its components in young adults conceived by ICSI","author":"Belva\n \nF\n,","year":"2018"},{"issue":"(1):","key":"CIT0021","series-title":"Hum Reprod","first-page":"232\u2013239","article-title":"American Heart Association ideal cardiovascular health score and subclinical atherosclerosis in 22-35-year-old adults conceived with and without assisted reproductive technologies","volume":"35","author":"Juonala\n \nM\n,","year":"2020"},{"issue":"(7):","key":"CIT0022","series-title":"PLoS One","first-page":"e0272064","article-title":"Cohort profile: the Growing Up Healthy Study (GUHS) \u2013 a prospective and observational cohort study investigating the long-term health outcomes of offspring conceived after assisted reproductive technologies","volume":"17","author":"Penova-Veselinovic\n \nB\n,","year":"2022"},{"key":"CIT0023","series-title":"WHO Child Growth Standards. Growth velocity based on weight, length and head circumference: methods and development","year":"2009"},{"issue":"(9):","key":"CIT0024","series-title":"J Clin Endocrinol Metab","first-page":"3441\u20133445","article-title":"In vitro fertilization improves childhood growth and metabolism","volume":"92","author":"Miles\n \nHL\n,","year":"2007"},{"issue":"(1):","key":"CIT0025","series-title":"Reprod Med Biol","first-page":"e12506","article-title":"Anthropometric measurements of term singletons at 6 years of age born from fresh and frozen embryo transfer: A multicenter prospective study in Japan","volume":"22","author":"Ueno\n \nK\n,","year":"2023"},{"issue":"(3):","key":"CIT0026","series-title":"Reprod Sci","first-page":"583\u2013590","article-title":"The long-term outcome of children conceived through assisted reproductive technology","volume":"31","author":"Ono\n \nM\n,","year":"2024"},{"issue":"(12):","key":"CIT0027","series-title":"PLoS Med","first-page":"e1004324","article-title":"Overweight or obesity in children born after assisted reproductive technologies in Denmark: a population-based cohort study","volume":"20","author":"Laugesen\n \nK\n,","year":"2023"},{"issue":"(6):","key":"CIT0028","series-title":"PLoS Med","first-page":"e1002817","article-title":"The association between maternal body mass index and child obesity: a systematic review and meta-analysis","volume":"16","author":"Heslehurst\n \nN\n,","year":"2019"},{"issue":"(4):","key":"CIT0029","series-title":"Bull Med Biol Res","first-page":"34\u201341","article-title":"Microbiological diagnostics: from traditional to molecular genetic methods: a literature review","volume":"5","author":"Ivashko\n \nM\n,","year":"2023"},{"issue":"(8):","key":"CIT0030","series-title":"Birth Defects Res","first-page":"630\u2013643","article-title":"Large for gestational age and macrosomia in singletons born after frozen\/thawed embryo transfer (FET) in assisted reproductive technology (ART)","volume":"110","author":"Berntsen\n \nS\n,","year":"2018"},{"issue":"(2):","key":"CIT0031","series-title":"Reprod Biomed Online","first-page":"300\u2013308","article-title":"Maternal and perinatal outcomes in programmed versus natural vitrified-warmed blastocyst transfer cycles","volume":"41","author":"Makhijani\n \nR\n,","year":"2020"},{"issue":"(2):","key":"CIT0032","series-title":"Am J Obstet Gynecol","first-page":"126.e1\u2013126.e18","article-title":"Neonatal and maternal outcome after frozen embryo transfer: Increased risks in programmed cycles","volume":"221","author":"Ernstad\n \nEG\n,","year":"2019"},{"issue":"(1):","key":"CIT0033","series-title":"J Pediatr Urol","first-page":"9\u201320","article-title":"Assisted reproductive technologies and the risk of congenital urogenital tract malformations: A systematic review and meta-analysis","volume":"17","author":"Zhang\n \nZ\n,","year":"2021"},{"issue":"(5\u00a0Suppl.):","key":"CIT0034","series-title":"J Urol","first-page":"1837\u20131842","article-title":"Does intracytoplasmic sperm injection pose an increased risk of genitourinary congenital malformations in offspring compared to in vitro fertilization? A systematic review and meta-analysis","volume":"193","author":"Massaro\n \nPA\n,","year":"2015"},{"issue":"(12):","key":"CIT0035","series-title":"Hum Reprod","first-page":"2811\u20132820","article-title":"Semen quality of young adult ICSI offspring: The first results","volume":"31","author":"Belva\n \nF\n,","year":"2016"},{"issue":"(1):","key":"CIT0036","series-title":"Bull Med Biol Res","first-page":"10\u201314","article-title":"Features of the blood supply of some areas of the head in human fetuses","volume":"5","author":"Komar\n \nTV\n,","year":"2023;"}],"container-title":["Qatar Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2025\/1\/article-9.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2025\/1\/article-9.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2025\/1\/article-9.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:16:54Z","timestamp":1777310214000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2025\/1\/article-9.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":72,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.5339\/qmj.2025.9","relation":{},"ISSN":["2227-0426"],"issn-type":[{"value":"2227-0426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}