{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:47:01Z","timestamp":1777312021936,"version":"3.51.4"},"reference-count":36,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"abstract":"\n Background:<\/jats:bold>\n Skin closure techniques in inguinal hernia surgery significantly influence postoperative outcomes, including pain, healing, scar formation, and patient satisfaction. The aim of this study is to evaluate the efficacy of\n N<\/jats:italic>\n -butyl-2-cyanoacrylate tissue adhesive as an alternative to conventional sutures for skin closure in inguinal hernia surgeries.\n <\/jats:p>\n \n Methods:<\/jats:bold>\n A prospective cross-sectional study was conducted at a tertiary care center from November 2023 to October 2025. Seventy patients aged 18\u201360 years undergoing inguinal hernia repair were randomly assigned to two groups: Group 1 (sutures) and Group 2 (tissue adhesive). Exclusion criteria included recurrent or strangulated hernia, allergies to cyanoacrylate\/formaldehyde, and immunocompromised states. Outcomes assessed included pain (VAS), wound healing (Hollander score), scar quality (Vancouver Scar Scale and Visual Analogue Scar Scale), complications, and satisfaction scores.\n <\/jats:p>\n \n Results:<\/jats:bold>\n Group 2 showed significantly lower pain scores at early postoperative intervals (\n p<\/jats:italic>\n < 0.05), shorter wound closure time (8.8 \u00b1 1.4 min vs. 11.7 \u00b1 2.6 min;\n p<\/jats:italic>\n = 0.000), and reduced hospital stay (1.9 \u00b1 0.8 days vs. 3.5 \u00b1 1.6 days;\n p<\/jats:italic>\n = 0.000). No infections were reported in either group. Chronic pain at 30 days was less frequent in Group 2 (\n p<\/jats:italic>\n = 0.046). Wound healing and scar scores favored Group 2 on days 7 and 30 (\n p<\/jats:italic>\n < 0.05). Patient satisfaction was higher in Group 2 across all follow-up visits, while surgeons preferred sutures (\n p<\/jats:italic>\n < 0.05).\n <\/jats:p>\n \n Conclusion:<\/jats:bold>\n N<\/jats:italic>\n -Butyl-2-cyanoacrylate tissue adhesive offers superior early postoperative outcomes and higher patient satisfaction compared to sutures, although surgeons reported greater satisfaction with traditional methods. Tissue adhesive is a viable alternative for skin closure in inguinal hernia surgeries.\n <\/jats:p>","DOI":"10.5339\/qmj.2026.12","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T21:30:34Z","timestamp":1773696634000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of N-butylcyanoacrylate glue and sutures for closure of inguinal skin incision after hernioplasty"],"prefix":"10.5339","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8123-3655","authenticated-orcid":true,"given":"Nandkishor D","family":"Shinde","sequence":"first","affiliation":[{"name":"Department of Surgery, Maharashtra Institute of Medical Sciences and Research (MIMSR), Latur, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6692-1759","authenticated-orcid":true,"given":"Afia","family":"Kausar","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, Department of Surgery, Khaja Bandanawaz University, Kalaburagi, Karnataka, India*Correspondance: Nandkishor D Shinde drnandkishorshinde@gmail.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9545-7203","authenticated-orcid":true,"given":"Anup S","family":"Desai","sequence":"additional","affiliation":[{"name":"Faculty of Medical Sciences, Department of Surgery, Khaja Bandanawaz University, Kalaburagi, Karnataka, India*Correspondance: Nandkishor D Shinde drnandkishorshinde@gmail.com"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3277","reference":[{"key":"B1","series-title":"SAGE Open Med","first-page":"20503121221139150","article-title":"Worldwide magnitude of inguinal hernia: Systematic review and meta-analysis of population-based studies","volume":"10:","author":"Abebe\n \nMS","year":"2022"},{"issue":"(1):","key":"B2","series-title":"Asian J Endosc Surg","first-page":"16\u201323","article-title":"Inguinal hernia repair: Toward Asian guidelines","volume":"8","author":"Lomanto\n \nD","year":"2015"},{"issue":"(3):","key":"B3","series-title":"Jurnalul de chirurgie","first-page":"301\u201319","article-title":"History of inguinal hernia repair","volume":"7","author":"Van Hee\n \nR","year":"2011"},{"issue":"(3):","key":"B4","series-title":"Int J Sci Stud","first-page":"45\u201353","article-title":"Comparison of wound closure using pctylcyanoacrylate tissue adhesive versus subcuticular suture in inguinal hernia surgery","volume":"7","author":"Singh\n \nJP","year":"2019"},{"key":"B5","series-title":"Int Surg J","first-page":"1165\u20137","article-title":"Comparison of tissue adhesive (N-butyl-2-cyanoacrylate) versus conventional suturing in umbilical hernia surgeries","volume":"8","author":"Dua\n \nA","year":"2021;"},{"issue":"(6):","key":"B6","series-title":"Int Wound J","first-page":"43\u201352","article-title":"A comparitive study of two skin closure techniques subcuticular monocryl and vertical mattress suture in cases posted for inguinoscrotal surgeries","volume":"18","author":"Haribabu\n \nA","year":"2019;"},{"issue":"(7):","key":"B7","series-title":"Burns","first-page":"1442\u20138","article-title":"What score on the Vancouver Scar Scale constitutes a hypertrophic scar? Results from a survey of North American burn-care providers","volume":"41","author":"Thompson\n \nCM","year":"2015"},{"issue":"(3):","key":"B8","series-title":"J Oral Biol Craniofac Res","first-page":"173\u20138","article-title":"Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study","volume":"9","author":"Sahu\n \nS","year":"2019"},{"issue":"(6):","key":"B9","series-title":"Plas Reconstr Surg","first-page":"2209\u201319","article-title":"Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery","volume":"102","author":"Toriumi\n \nDM","year":"1998"},{"issue":"(1):","key":"B10","series-title":"Sci Rep","first-page":"11786","article-title":"Glued suture-less peritoneum closure in laparoscopic inguinal hernia repair reduces acute postoperative pain","volume":"14","author":"Huguenin-Dezot\n \nM","year":"2024"},{"issue":"(3):","key":"B11","series-title":"Can J Surg","first-page":"155\u201360","article-title":"A single-surgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair","volume":"53","author":"Testini\n \nM","year":"2010"},{"issue":"(2):","key":"B12","series-title":"J Minim Access Surg","first-page":"118\u201323","article-title":"Randomised controlled trial of n-butyl cyanoacrylate glue fixation versus suture fixation of mesh in laparoscopic totally extraperitoneal hernia repair","volume":"12","author":"Jani\n \nK","year":"2016"},{"issue":"(4):","key":"B13","series-title":"J Clin Neurosci","first-page":"535\u20139","article-title":"Use of skin glue versus traditional wound closure methods in brain surgery: A prospective, randomized, controlled study","volume":"16","author":"Chibbaro\n \nS","year":"2009"},{"issue":"(5\u20136):","key":"B14","series-title":"Pediatr Surg Int","first-page":"553\u20135","article-title":"Comparing wound closure using tissue glue versus subcuticular suture for pediatric surgical incisions: A prospective, randomised trial","volume":"18","author":"Ong\n \nCC","year":"2002"},{"issue":"(9):","key":"B15","series-title":"Arch Dermatol","first-page":"1177\u201380","article-title":"A prospective comparison of octyl cyanoacrylate tissue adhesive (dermabond) and suture for the closure of excisional wounds in children and adolescents","volume":"137","author":"Bernard\n \nL","year":"2001"},{"issue":"(4):","key":"B16","series-title":"Am J Obstet Gynecol","first-page":"406-e1\u2013406.e5","article-title":"Skin closure at cesarean delivery, glue vs subcuticular sutures: a randomized controlled trial","volume":"216","author":"Daykan\n \nY","year":"2017"},{"issue":"(3):","key":"B17","series-title":"Surgery","first-page":"270\u20136","article-title":"Closure of lacerations and incisions with octylcyanoacrylate: A multicenter randomized controlled trial","volume":"131","author":"Singer\n \nAJ","year":"2002"},{"issue":"(1):","key":"B18","series-title":"Natl J Maxillofac Surg","first-page":"15\u20139","article-title":"Comparison of octyl-2-cyanoacrylate and conventional sutures in facial skin closure","volume":"1","author":"Shivamurthy\n \nDM","year":"2010"},{"key":"B1","series-title":"SAGE Open Med","first-page":"20503121221139150","article-title":"Worldwide magnitude of inguinal hernia: Systematic review and meta-analysis of population-based studies","volume":"10:","author":"Abebe\n \nMS","year":"2022"},{"issue":"(1):","key":"B2","series-title":"Asian J Endosc Surg","first-page":"16\u201323","article-title":"Inguinal hernia repair: Toward Asian guidelines","volume":"8","author":"Lomanto\n \nD","year":"2015"},{"issue":"(3):","key":"B3","series-title":"Jurnalul de chirurgie","first-page":"301\u201319","article-title":"History of inguinal hernia repair","volume":"7","author":"Van Hee\n \nR","year":"2011"},{"issue":"(3):","key":"B4","series-title":"Int J Sci Stud","first-page":"45\u201353","article-title":"Comparison of wound closure using pctylcyanoacrylate tissue adhesive versus subcuticular suture in inguinal hernia surgery","volume":"7","author":"Singh\n \nJP","year":"2019"},{"key":"B5","series-title":"Int Surg J","first-page":"1165\u20137","article-title":"Comparison of tissue adhesive (N-butyl-2-cyanoacrylate) versus conventional suturing in umbilical hernia surgeries","volume":"8","author":"Dua\n \nA","year":"2021;"},{"issue":"(6):","key":"B6","series-title":"Int Wound J","first-page":"43\u201352","article-title":"A comparitive study of two skin closure techniques subcuticular monocryl and vertical mattress suture in cases posted for inguinoscrotal surgeries","volume":"18","author":"Haribabu\n \nA","year":"2019;"},{"issue":"(7):","key":"B7","series-title":"Burns","first-page":"1442\u20138","article-title":"What score on the Vancouver Scar Scale constitutes a hypertrophic scar? Results from a survey of North American burn-care providers","volume":"41","author":"Thompson\n \nCM","year":"2015"},{"issue":"(3):","key":"B8","series-title":"J Oral Biol Craniofac Res","first-page":"173\u20138","article-title":"Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study","volume":"9","author":"Sahu\n \nS","year":"2019"},{"issue":"(6):","key":"B9","series-title":"Plas Reconstr Surg","first-page":"2209\u201319","article-title":"Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery","volume":"102","author":"Toriumi\n \nDM","year":"1998"},{"issue":"(1):","key":"B10","series-title":"Sci Rep","first-page":"11786","article-title":"Glued suture-less peritoneum closure in laparoscopic inguinal hernia repair reduces acute postoperative pain","volume":"14","author":"Huguenin-Dezot\n \nM","year":"2024"},{"issue":"(3):","key":"B11","series-title":"Can J Surg","first-page":"155\u201360","article-title":"A single-surgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair","volume":"53","author":"Testini\n \nM","year":"2010"},{"issue":"(2):","key":"B12","series-title":"J Minim Access Surg","first-page":"118\u201323","article-title":"Randomised controlled trial of n-butyl cyanoacrylate glue fixation versus suture fixation of mesh in laparoscopic totally extraperitoneal hernia repair","volume":"12","author":"Jani\n \nK","year":"2016"},{"issue":"(4):","key":"B13","series-title":"J Clin Neurosci","first-page":"535\u20139","article-title":"Use of skin glue versus traditional wound closure methods in brain surgery: A prospective, randomized, controlled study","volume":"16","author":"Chibbaro\n \nS","year":"2009"},{"issue":"(5\u20136):","key":"B14","series-title":"Pediatr Surg Int","first-page":"553\u20135","article-title":"Comparing wound closure using tissue glue versus subcuticular suture for pediatric surgical incisions: A prospective, randomised trial","volume":"18","author":"Ong\n \nCC","year":"2002"},{"issue":"(9):","key":"B15","series-title":"Arch Dermatol","first-page":"1177\u201380","article-title":"A prospective comparison of octyl cyanoacrylate tissue adhesive (dermabond) and suture for the closure of excisional wounds in children and adolescents","volume":"137","author":"Bernard\n \nL","year":"2001"},{"issue":"(4):","key":"B16","series-title":"Am J Obstet Gynecol","first-page":"406-e1\u2013406.e5","article-title":"Skin closure at cesarean delivery, glue vs subcuticular sutures: a randomized controlled trial","volume":"216","author":"Daykan\n \nY","year":"2017"},{"issue":"(3):","key":"B17","series-title":"Surgery","first-page":"270\u20136","article-title":"Closure of lacerations and incisions with octylcyanoacrylate: A multicenter randomized controlled trial","volume":"131","author":"Singer\n \nAJ","year":"2002"},{"issue":"(1):","key":"B18","series-title":"Natl J Maxillofac Surg","first-page":"15\u20139","article-title":"Comparison of octyl-2-cyanoacrylate and conventional sutures in facial skin closure","volume":"1","author":"Shivamurthy\n \nDM","year":"2010"}],"container-title":["Qatar Medical Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2026\/1\/article-12.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2026\/1\/article-12.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.qscience.com\/downloadpdf\/journals\/qmj\/2026\/1\/article-12.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:09:54Z","timestamp":1777309794000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.qscience.com\/view\/journals\/qmj\/2026\/1\/article-12.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":36,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.5339\/qmj.2026.12","relation":{},"ISSN":["2227-0426"],"issn-type":[{"value":"2227-0426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}