{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T10:26:34Z","timestamp":1787048794032,"version":"build-2736575974"},"reference-count":14,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"3","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Antimicrobial resistance (AMR) is a critical global health threat. Local, real-time epidemiological data are the cornerstone of effective antimicrobial stewardship. This study aimed to establish a 2024 baseline for AMR patterns at a major tertiary care center in Qatar to directly guide empirical therapy and stewardship interventions.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    We conducted a retrospective, cross-sectional analysis of 1,656 positive bacterial cultures from blood, urine, and wound samples collected from 1,218 patients between January 1 and December 31, 2024. Antibiotic susceptibility testing was interpreted per European Committee on Antimicrobial Susceptibility Testing (EUCAST) 2024 guidelines. Statistical analysis utilized descriptive statistics and Chi-square tests.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    The most common pathogens were Escherichia coli (30.0%), Staphylococcus aureus (25.0%), and Pseudomonas aeruginosa (15.0%). High resistance rates were observed, with E. coli exhibiting resistance to ceftriaxone (45.0%, 95% CI 40.5\u201349.5) and ciprofloxacin (50.0%, 95% CI 45.5\u201354.5). Methicillin-resistant S. aureus (MRSA) prevalence was 30.0% (95% CI 25.6\u201334.7). Carbapenem-resistant Klebsiella pneumoniae (CRKP) accounted for 5.5% (95% CI 4.4\u20136.7) of all isolates. Multidrug-resistant organisms (MDROs) were identified in 35.0% (95% CI 32.7\u201337.3) of samples, with a significantly higher prevalence in intensive care units (ICUs) (45.0%) compared to other wards (p &lt; 0.001).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    This study documents a high burden of AMR, dominated by Gram-negative pathogens in critical care settings. These findings necessitate a multi-pronged response, including the revision of empirical antibiotic guidelines, enhanced stewardship focused on high-risk agents, and intensified infection control in ICUs. Integrating molecular epidemiology into future prospective surveillance is essential to combat this escalating crisis.\n                  <\/jats:p>","DOI":"10.5339\/qmj.2026.52","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T09:42:02Z","timestamp":1787046122000},"source":"Crossref","is-referenced-by-count":0,"title":["Antimicrobial resistance patterns in a Qatari tertiary care center in 2024: A retrospective study"],"prefix":"10.5339","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6858-3375","authenticated-orcid":true,"given":"Bassem Al","family":"Hariri","sequence":"first","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"},{"name":"College of Medicine, Weill Cornell Medicine, Doha, Qatar"},{"name":"College of Medicine, Qatar University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Eid Nazzal","family":"Alharafsheh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joudi","family":"Alhariri","sequence":"additional","affiliation":[{"name":"College of Medicine, Syrian Private University, Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Mousa","family":"Alnaimat","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Barman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"},{"name":"College of Medicine, Weill Cornell Medicine, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muad Abdi","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatem Mabrouk Taher","family":"Abusriwil","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3277","reference":[{"issue":"10325:","key":"B1","series-title":"The Lancet","first-page":"629","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Murray\n \nCJL","year":"2022;","unstructured":"Murray\n \nCJL\n\n, \n\nIkuta\n \nKS\n\n, \n\nSharara\n \nF\n\n, \n\nSwetschinski\n \nL\n\n, \n\nAguilar\n \nGR\n\n, \n\nGray\n \nA\n\n\n\n. \nGlobal burden of bacterial antimicrobial resistance in 2019: a systematic analysis\n. \nThe Lancet\n. \n2022;\n399\n10325:\n629\n655\n. \n\nhttps:\/\/doi.org\/10.1016\/S0140-6736(21)02724-0"},{"issue":"1:","key":"B2","series-title":"Open Vet J","first-page":"577","article-title":"Antimicrobial resistance from one health perspective in the Middle East: A systematic review","volume":"14","author":"Alkheraije\n \nKA","year":"2024","unstructured":"Alkheraije\n \nKA\n\n\n. \nAntimicrobial resistance from one health perspective in the Middle East: A systematic review\n. \nOpen Vet J\n. \n2024\nJan;\n14\n1:\n577\n585\n. \n\nhttps:\/\/doi.org\/10.5455\/OVJ.2024.v14.i1.53"},{"key":"B3","series-title":"Front. 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