{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T17:47:14Z","timestamp":1777312034981,"version":"3.51.4"},"reference-count":66,"publisher":"Hamad bin Khalifa University Press (HBKU Press)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Malignant mesothelioma (MM) is a potentially fatal cancer that originates from the mesothelial surfaces, predominantly the pleura. Asbestos is the principal risk factor with a long latency period between exposure and disease development. The objective of this study was to investigate the clinical and epidemiological characteristics of MM in the State of Qatar.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methodology:<\/jats:bold>\n                    This was a retrospective cohort study of all MM cases diagnosed in the State of Qatar during the period from January 1, 2015, to December 31, 2023. MM cases were identified from the Qatari National Cancer Registry Database and the Hamad Medical Corporation (HMC) Histopathology Database. Demographic, clinical, laboratory, radiologic, and survival data were collected from these two databases.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Among the total 22 MM cases diagnosed during the study period, migrant Egyptians constituted 15\/22 (68.2%). The mean age for the study population was 57.9 \u00b1 9.2 years with an age-standardized incidence rate of 24.1 cases per 1,000,000 individuals per year. The epithelioid histologic type was the predominant type (16\/19; 84.2%), and most patients (13\/14; 92.9%) were diagnosed at an advanced disease stage. The median overall survival (OS) was 16 months. The 1-year OS rate was 60.67%, dropping to 20.22% over 3 years. Though the differences were not statistically significant, patients with epithelioid histology and those with left-sided tumors experienced better OS outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    MM is predominantly a cancer of Egyptian migrants in the State of Qatar, with a comparable incidence to the international rates. Epithelioid histologic type is the most common type in the State of Qatar, and the majority of patients are diagnosed at an advanced disease stage. Despite a better OS rate compared to other countries, the prognosis of MM remains grave.\n                  <\/jats:p>","DOI":"10.5339\/qmj.2026.7","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T21:30:26Z","timestamp":1772659826000},"source":"Crossref","is-referenced-by-count":0,"title":["Malignant mesothelioma in the State of Qatar: A clinico-epidemiological study"],"prefix":"10.5339","volume":"2026","author":[{"given":"Wanis H.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"College of Medicine & Weill Cornell Medicine, Doha, Qatar"},{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuha","family":"Fituri","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadin H.","family":"Abouzeid","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saif Addeen","family":"Khasawneh","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Elgara","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musa","family":"Hussein","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Issam A.","family":"Bozom","sequence":"additional","affiliation":[{"name":"Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyad","family":"Mohsen","sequence":"additional","affiliation":[{"name":"National Centre of Cancer Care, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafedh","family":"Ghazouani","sequence":"additional","affiliation":[{"name":"Quality Management and Improvement Department, Hamad Medical Corporation, Doha, Qatar*Correspondance: Wanis H. Ibrahim wanisian@yahoo.com"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3277","reference":[{"issue":"(1):","key":"B1","series-title":"Ochsner J","first-page":"70\u20139","article-title":"Mesothelioma: a review","volume":"12","author":"Mott\n \nFE","year":"2012"},{"issue":"(5):","key":"B2","series-title":"Ann Epidemiol","first-page":"348\u201359.e11","article-title":"Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis","volume":"27","author":"Mezei\n \nG","year":"2017"},{"issue":"(1):","key":"B3","series-title":"Semin Oncol","first-page":"18\u201325","article-title":"The epidemiology of mesothelioma","volume":"29","author":"Britton\n \nM","year":"2002"},{"issue":"(11):","key":"B4","series-title":"Occup Environ Med","first-page":"760\u20135","article-title":"Incidence of extrapleural malignant mesothelioma and asbestos exposure, from the Italian national register","volume":"67","author":"Marinaccio\n \nA","year":"2010"},{"issue":"(9):","key":"B5","series-title":"Ann Epidemiol","first-page":"688\u201397","article-title":"Mesothelioma from chrysotile asbestos: update","volume":"21","author":"Kanarek\n \nMS","year":"2011"},{"issue":"(7-8):","key":"B6","series-title":"Autoimmun Rev","first-page":"103603","article-title":"Amphibole asbestos as an environmental trigger for systemic autoimmune diseases","volume":"23","author":"Pfau\n \nJC","year":"2024"},{"issue":"(7):","key":"B7","series-title":"J Occup Med","first-page":"718\u201321","article-title":"Latent period for malignant mesothelioma of occupational origin","volume":"34","author":"Lanphear\n \nBP","year":"1992"},{"issue":"(2):","key":"B8","series-title":"Tumori","first-page":"210\u20134","article-title":"Asbestos and SV40 in malignant pleural mesothelioma from a hyperendemic area of north-eastern Italy","volume":"98","author":"Comar\n \nM","year":"2012"},{"issue":"(6B):","key":"B9","series-title":"Anticancer Res","first-page":"4159\u201361","article-title":"No detection of SV40 DNA in mesothelioma tissues from a high incidence area in Sweden","volume":"27","author":"Lundstig\n \nA","year":"2007"},{"issue":"(6):","key":"B10","series-title":"Rev Pneumol Clin","first-page":"427\u201335","article-title":"[Clinical and pathological profile of the pleural malignant mesothelioma: a retrospective study about 30 cases]","volume":"74","author":"Mlika\n \nM","year":"2018"},{"key":"B11","series-title":"In: StatPearls [Internet]","article-title":"Malignant Mesothelioma","author":"Syed\n \nHA","year":"2025"},{"key":"B12","series-title":"Airborne Asbestos Health Assessment Update","author":"United States Environmental Protection Agency","year":"1986"},{"issue":"(7)","key":"B13","series-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans","first-page":"106\u201316","volume":"Vol. 42","author":"International Agency for Research on Cancer"},{"issue":"(1):","key":"B14","series-title":"Ann Occup Environ Med","first-page":"10","article-title":"Systematic review of the effects of asbestos exposure on the risk of cancer between children and adults","volume":"25","author":"Kang\n \nD","year":"2013"},{"key":"B15","series-title":"Countries with asbestos bans","author":"Asbestos and Silica Safety and Eradication Agency. Australian Government"},{"key":"B16","series-title":"Age Standardization of Rates: A New WHO Standard","author":"Ahmad\n \nO","year":"2001"},{"issue":"(1-2):","key":"B17","series-title":"Middle East Law Govern","first-page":"36\u201370","article-title":"Labour migration from Asian to GCC countries: Trends, patterns and policies","volume":"5","author":"Shah\n \nNM","year":"2013"},{"issue":"(6):","key":"B18","series-title":"A ten-year (1998-2007) multicentre study. Arch Med Sci","first-page":"926\u201331","article-title":"Epidemiology of mesothelioma in Egypt","volume":"6","author":"Akl\n \nY","year":"2010"},{"issue":"(1):","key":"B19","series-title":"Thorac Cancer","first-page":"16\u201323","article-title":"Malignant pleural mesothelioma: a retrospective analysis of clinicopathological and survival data","volume":"2","author":"Adel\n \nAM","year":"2011"},{"issue":"(4):","key":"B20","series-title":"Atmos Pollut Res","first-page":"445\u201351","article-title":"Airborne asbestos fibres and mesothelioma in the last 20 years in Egypt: a review","volume":"2","author":"Awad\n \nAH","year":"2011"},{"issue":"Suppl 1:","key":"B21","series-title":"Lung Cancer","first-page":"S17\u201320","article-title":"Epidemic of mesothelioma in Egypt","volume":"49","author":"Gaafar\n \nRM","year":"2005"},{"issue":"(7):","key":"B22","series-title":"Environments","first-page":"76","article-title":"Epidemiology of mesothelioma","volume":"6","author":"Cavone\n \nD","year":"2019"},{"issue":"(17\u201318):","key":"B23","series-title":"Wien Klin Wochenschr","first-page":"611\u20137","article-title":"Management of malignant pleural mesothelioma - part 1: Epidemiology, diagnosis, and staging : Consensus of the Austrian Mesothelioma Interest Group (AMIG)","volume":"128","author":"Geltner\n \nC","year":"2016"},{"issue":"(3-4):","key":"B24","series-title":"Br J Cancer","first-page":"666\u201372","article-title":"The European mesothelioma epidemic","volume":"79","author":"Peto\n \nJ","year":"1999"},{"issue":"(3):","key":"B25","series-title":"Am J Ind Med","first-page":"188\u2013201","article-title":"Malignant mesothelioma in Australia, 1945-2000","volume":"41","author":"Leigh\n \nJ","year":"2002"},{"issue":"(2):","key":"B26","series-title":"Indian J Occup Environ Med","first-page":"82\u20138","article-title":"Global mesothelioma epidemic: trend and features","volume":"18","author":"Bianchi\n \nC","year":"2014"},{"issue":"(8):","key":"B27","series-title":"Scand J Public Health","first-page":"875\u201381","article-title":"Emerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden","volume":"43","author":"J\u00e4rvholm\n \nB","year":"2015"},{"issue":"(11):","key":"B28","series-title":"Cancer Med","first-page":"12208\u201320","article-title":"Epidemiological, therapeutic, and survival trends in malignant pleural mesothelioma: a review of the National Cancer Database","volume":"12","author":"Bou-Samra\n \nP","year":"2023"},{"issue":"(1):","key":"B29","series-title":"Thorac Cancer","first-page":"16\u201323","article-title":"Malignant pleural mesothelioma: a retrospective analysis of clinicopathological and survival data","volume":"2","author":"Adel\n \nAM","year":"2011"},{"issue":"(12):","key":"B30","series-title":"Thorax","first-page":"1260\u20137","article-title":"Incidence, treatment and survival of malignant pleural and peritoneal mesothelioma: a population-based study","volume":"77","author":"van Kooten\n \nJP","year":"2022"},{"issue":"(2):","key":"B31","series-title":"J R Coll Physicians Edinb","first-page":"123\u20136","article-title":"Survival from malignant mesothelioma: where are we now?","volume":"45","author":"Marshall\n \nAD","year":"2015;"},{"issue":"(3):","key":"B32","series-title":"Oman Med J","first-page":"e276","article-title":"Featuring trends in the epidemiology of lung cancer following the publication of the national cancer strategy in Qatar","volume":"36","author":"Ibrahim\n \nWH","year":"2021"},{"issue":"(1):","key":"B33","series-title":"J Clin Oncol","first-page":"145\u201352","article-title":"Prognostic factors in patients with pleural mesothelioma: the European Organization for Research and Treatment of Cancer experience","volume":"16","author":"Curran\n \nD","year":"1998"},{"issue":"(1):","key":"B1","series-title":"Ochsner J","first-page":"70\u20139","article-title":"Mesothelioma: a review","volume":"12","author":"Mott\n \nFE","year":"2012"},{"issue":"(5):","key":"B2","series-title":"Ann Epidemiol","first-page":"348\u201359.e11","article-title":"Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis","volume":"27","author":"Mezei\n \nG","year":"2017"},{"issue":"(1):","key":"B3","series-title":"Semin Oncol","first-page":"18\u201325","article-title":"The epidemiology of mesothelioma","volume":"29","author":"Britton\n \nM","year":"2002"},{"issue":"(11):","key":"B4","series-title":"Occup Environ Med","first-page":"760\u20135","article-title":"Incidence of extrapleural malignant mesothelioma and asbestos exposure, from the Italian national register","volume":"67","author":"Marinaccio\n \nA","year":"2010"},{"issue":"(9):","key":"B5","series-title":"Ann Epidemiol","first-page":"688\u201397","article-title":"Mesothelioma from chrysotile asbestos: update","volume":"21","author":"Kanarek\n \nMS","year":"2011"},{"issue":"(7-8):","key":"B6","series-title":"Autoimmun Rev","first-page":"103603","article-title":"Amphibole asbestos as an environmental trigger for systemic autoimmune diseases","volume":"23","author":"Pfau\n \nJC","year":"2024"},{"issue":"(7):","key":"B7","series-title":"J Occup Med","first-page":"718\u201321","article-title":"Latent period for malignant mesothelioma of occupational origin","volume":"34","author":"Lanphear\n \nBP","year":"1992"},{"issue":"(2):","key":"B8","series-title":"Tumori","first-page":"210\u20134","article-title":"Asbestos and SV40 in malignant pleural mesothelioma from a hyperendemic area of north-eastern Italy","volume":"98","author":"Comar\n \nM","year":"2012"},{"issue":"(6B):","key":"B9","series-title":"Anticancer Res","first-page":"4159\u201361","article-title":"No detection of SV40 DNA in mesothelioma tissues from a high incidence area in Sweden","volume":"27","author":"Lundstig\n \nA","year":"2007"},{"issue":"(6):","key":"B10","series-title":"Rev Pneumol Clin","first-page":"427\u201335","article-title":"[Clinical and pathological profile of the pleural malignant mesothelioma: a retrospective study about 30 cases]","volume":"74","author":"Mlika\n \nM","year":"2018"},{"key":"B11","series-title":"In: StatPearls [Internet]","article-title":"Malignant Mesothelioma","author":"Syed\n \nHA","year":"2025"},{"key":"B12","series-title":"Airborne Asbestos Health Assessment Update","author":"United States Environmental Protection Agency","year":"1986"},{"issue":"(7)","key":"B13","series-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans","first-page":"106\u201316","volume":"Vol. 42","author":"International Agency for Research on Cancer"},{"issue":"(1):","key":"B14","series-title":"Ann Occup Environ Med","first-page":"10","article-title":"Systematic review of the effects of asbestos exposure on the risk of cancer between children and adults","volume":"25","author":"Kang\n \nD","year":"2013"},{"key":"B15","series-title":"Countries with asbestos bans","author":"Asbestos and Silica Safety and Eradication Agency. Australian Government"},{"key":"B16","series-title":"Age Standardization of Rates: A New WHO Standard","author":"Ahmad\n \nO","year":"2001"},{"issue":"(1-2):","key":"B17","series-title":"Middle East Law Govern","first-page":"36\u201370","article-title":"Labour migration from Asian to GCC countries: Trends, patterns and policies","volume":"5","author":"Shah\n \nNM","year":"2013"},{"issue":"(6):","key":"B18","series-title":"A ten-year (1998-2007) multicentre study. 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