{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T13:24:44Z","timestamp":1747229084198,"version":"3.40.5"},"reference-count":0,"publisher":"POLEMOS S.A.","issue":"160","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vertex Rev Arg Psiquiatr"],"abstract":"<jats:p>El espectro de enfermedades neurodegenerativas que afectan principalmente a la cognici\u00f3n y el comportamiento abarca desde la enfermedad precl\u00ednica asintom\u00e1tica hasta el deterioro cognitivo muy leve y la demencia franca. La enfermedad de Alzheimer (EA) es la causa m\u00e1s com\u00fan de deterioro de la capacidad cognitiva. Es una enfermedad devastadora que afecta a los pacientes y a toda su familia de cuidadores, lo que supone enormes dificultades socioecon\u00f3micas y psicoemocionales. El diagn\u00f3stico puede complicarse debido a otras formas de demencia que presentan s\u00edntomas y patolog\u00edas similares a la EA. Los marcadores bioqu\u00edmicos para identificar la enfermedad de Alzheimer desempe\u00f1an un papel central en los nuevos criterios diagn\u00f3sticos de la enfermedad y en la reciente definici\u00f3n biol\u00f3gica de la EA. Conocer las caracter\u00edsticas claves y la patolog\u00eda de cada tipo de demencia puede ayudar en el diagn\u00f3stico preciso de los pacientes, a fin de que reciban el tratamiento y los servicios de apoyo adecuados a su condici\u00f3n y mantengan el mayor funcionamiento posible en la vida diaria y la calidad de vida. Por lo tanto es prioritario diferenciar, bas\u00e1ndose en criterios cl\u00ednicos, neuropatolog\u00eda y biomarcadores, la EA y sus variantes at\u00edpicas de otras demencias comunes como el Deterioro Cognitivo Vascular, la Degeneraci\u00f3n Fronto- temporal entre otras, y los trastornos cognitivos menos frecuentes. Este art\u00edculo de revisi\u00f3n presenta datos actualizados relativos a los recientes criterios diagn\u00f3sticos de algunas formas de demencia haciendo hincapi\u00e9 en su utilidad en la pr\u00e1ctica cl\u00ednica habitual. Se exponen los criterios de EA, de Demencia Vascular (DV), de la demencia Fronto-temporal (DFT) y de una forma rara de demencia, descripta en los \u00faltimos a\u00f1os, que se evidencia en pacientes muy a\u00f1osos con un perfil similar a la EA. Se trata de la encefalopat\u00eda predominantemente l\u00edmbica por tdp- 43 relacionada a la edad (LATE).<\/jats:p>","DOI":"10.53680\/vertex.v34i160.460","type":"journal-article","created":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T15:08:36Z","timestamp":1690211316000},"page":"54-78","source":"Crossref","is-referenced-by-count":0,"title":["Criterios diagn\u00f3sticos en la enfermedad demencial \u00bfQu\u00e9 hay de nuevo?"],"prefix":"10.53680","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0879-3397","authenticated-orcid":false,"given":"Edith","family":"Labos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Ver\u00f3nica","family":"Bavec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4334-7795","authenticated-orcid":false,"given":"Diana","family":"Cristalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6939-455X","authenticated-orcid":false,"given":"Florencia","family":"Deschle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5791-3148","authenticated-orcid":false,"given":"Cristian","family":"Isaac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0281-6153","authenticated-orcid":false,"given":"Guido","family":"Dorman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7851-9094","authenticated-orcid":false,"given":"Juan","family":"Ollari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Rubi\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2347-9731","authenticated-orcid":false,"given":"Mar\u00eda Julieta","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31787","published-online":{"date-parts":[[2023,7,10]]},"container-title":["Vertex Revista Argentina de Psiquiatr\u00eda"],"original-title":[],"link":[{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/460\/403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/460\/403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T15:08:36Z","timestamp":1690211316000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/view\/460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,10]]},"references-count":0,"journal-issue":{"issue":"160","published-online":{"date-parts":[[2023,7,10]]}},"URL":"https:\/\/doi.org\/10.53680\/vertex.v34i160.460","relation":{},"ISSN":["2718-904X","0327-6139"],"issn-type":[{"type":"electronic","value":"2718-904X"},{"type":"print","value":"0327-6139"}],"subject":[],"published":{"date-parts":[[2023,7,10]]}}}