{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:18:40Z","timestamp":1791357520212,"version":"4.3.1"},"reference-count":0,"publisher":"POLEMOS S.A.","issue":"167","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vertex Rev Arg Psiquiatr"],"abstract":"<jats:p>Objetivo: Identificar patrones de prescripci\u00f3n psicofarmacol\u00f3gica en usuarios mayores de 18 a\u00f1os del Hospital \u201cDr. Alejandro Korn\u201d de La Plata, Argentina. Metodolog\u00eda: Estudio observacional, descriptivo, transversal. Se relevaron las prescripciones de psicof\u00e1rmacos de personas internadas y ambulatorias. Resultados: 425 usuarios (71 % masculinos), 218 eran ambulatorios en centros de salud mental comunitarios o en las salas; 207 internados en salas de larga (n=86), media (n=34) y corta estancia (n=87), con una mediana (rango) de internaci\u00f3n de 9.5 (1-53.3) a\u00f1os. Los diagn\u00f3sticos m\u00e1s prevalentes fueron esquizofrenia y otras psicosis (71.1 % ) y retraso mental (16.7 %). El 94.6 % recib\u00edan antipsic\u00f3ticos (AP), con 43.1 % de primera generaci\u00f3n (APG) y 77.2 % de segunda generaci\u00f3n; 74.6 % sedantes\/hipn\u00f3ticos, principalmente benzodiazepinas; 42.6 % anticonvulsivantes y 13.4 % antidepresivos. La polifarmacia antipsic\u00f3tica (\u22652 AP) fue de 42.3 %, alcanzando 69.9 % en usuarios de APG. La dosis de AP fue \u2265600 mg equivalentes de clorpromazina (eqCPZ) en 62.9 % y \u22651200 mg eqCPZ en 25.9 %. El 22.4 % de los usuarios de AP recib\u00edan biperideno. Conclusiones: existe una elevada frecuencia de polifarmacia AP, altas dosis de AP y uso de APG.Tambi\u00e9n prescripci\u00f3n frecuente de benzodiazepinas. Es prioritario evaluar la reducci\u00f3n de dosis y deprescripci\u00f3n de los diferentes grupos farmacol\u00f3gicos.\u00a0<\/jats:p>","DOI":"10.53680\/vertex.v36i167.796","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T16:23:13Z","timestamp":1744302193000},"page":"6-16","source":"Crossref","is-referenced-by-count":1,"title":["Patrones de prescripci\u00f3n de psicof\u00e1rmacos en usuarios internados y en atenci\u00f3n ambulatoria comunitaria en el hospital neuropsiqui\u00e1trico \u201cDr. Alejandro Korn\u201d, La Plata, Argentina. Estudio de corte transversal"],"prefix":"10.53680","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6477-9959","authenticated-orcid":false,"given":"Pedro Dami\u00e1n","family":"Gargoloff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6018-8250","authenticated-orcid":false,"given":"Mart\u00edn A.","family":"Urtasun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9579-3667","authenticated-orcid":false,"given":"Ra\u00fal","family":"Riveros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0413-7004","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0500-5866","authenticated-orcid":false,"given":"Mart\u00edn","family":"Ca\u00f1\u00e1s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"31787","published-online":{"date-parts":[[2025,4,10]]},"container-title":["Vertex Revista Argentina de Psiquiatr\u00eda"],"original-title":[],"link":[{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/796\/659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/796\/659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T16:23:13Z","timestamp":1744302193000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/view\/796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,10]]},"references-count":0,"journal-issue":{"issue":"167","published-online":{"date-parts":[[2025,4,10]]}},"URL":"https:\/\/doi.org\/10.53680\/vertex.v36i167.796","relation":{},"ISSN":["2718-904X","0327-6139"],"issn-type":[{"value":"2718-904X","type":"electronic"},{"value":"0327-6139","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,10]]}}}