{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T17:42:29Z","timestamp":1768066949990,"version":"3.49.0"},"reference-count":0,"publisher":"POLEMOS S.A.","issue":"170","license":[{"start":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:00:00Z","timestamp":1768003200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vertex Rev Arg Psiquiatr"],"abstract":"<jats:p>La enfermedad demencial se caracteriza por un deterioro progresivo de las habilidades cognitivas y funcionales. Si bien la demencia de mayor prevalencia es la Enfermedad de Alzheimer el amplio espectro de otras formas de presentaci\u00f3n como la demencia vascular, la demencia frontotemporal o la demencia por cuerpos de Lewy, entre otras, implica un gran desaf\u00edo diagn\u00f3stico. Esta instancia resulta altamente complicada ya que generalmente la enfermedad demencial se presenta en sus inicios con una variada superposici\u00f3n de manifestaciones cl\u00ednicas y cognitivas, as\u00ed como con una gran heterogeneidad en los hallazgos en las exploraciones de im\u00e1genes por resonancia magn\u00e9tica que hace dif\u00edcil su precisi\u00f3n. Se describen los perfiles cognitivos de la enfermedad de Alzheimer, la demencia vascular, la demencia frontotemporal en su variable conductual, la demencia con cuerpos de Lewy, las demencias focales como las afasias progresivas primarias, la demencia por enfermedad de Parkinson y el LATE, demencia tard\u00eda con gran similitud a la EA. Considerando que no siempre es posible acceder a estudios de complejidad como los biomarcadores o neuroim\u00e1genes, el objetivo del presente trabajo es brindar un panorama actual de los perfiles cognitivos de inicio y progresi\u00f3n que resulte de utilidad cl\u00ednica y que oriente a un posible diagn\u00f3stico diferencial.<\/jats:p>","DOI":"10.53680\/vertex.v36i170.943","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T14:51:53Z","timestamp":1768056713000},"page":"41-63","source":"Crossref","is-referenced-by-count":0,"title":["Perfiles cognitivos en las demencias"],"prefix":"10.53680","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0879-3397","authenticated-orcid":false,"given":"Edith","family":"Labos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4334-7795","authenticated-orcid":false,"given":"Diana","family":"Cristalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6939-455X","authenticated-orcid":false,"given":"Florencia","family":"Deschle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana","family":"Colli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0119-7074","authenticated-orcid":false,"given":"Waleska","family":"Berrios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0281-6153","authenticated-orcid":false,"given":"Guido","family":"Dorman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2312-0163","authenticated-orcid":false,"given":"Mar\u00eda Cecilia","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvina","family":"Frontera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7421-0598","authenticated-orcid":false,"given":"Marcelo","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Mangone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"M\u00e1rquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7279-6245","authenticated-orcid":false,"given":"Oscar","family":"Porta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5967-4950","authenticated-orcid":false,"given":"Valeria","family":"Rubi\u00f1o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2347-9731","authenticated-orcid":false,"given":"Mar\u00eda Julieta","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7851-9094","authenticated-orcid":false,"given":"Juan","family":"Ollari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"31787","published-online":{"date-parts":[[2026,1,10]]},"container-title":["Vertex Revista Argentina de Psiquiatr\u00eda"],"original-title":[],"link":[{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/943\/732","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/download\/943\/732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T14:51:53Z","timestamp":1768056713000},"score":1,"resource":{"primary":{"URL":"https:\/\/revistavertex.com.ar\/ojs\/index.php\/vertex\/article\/view\/943"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,10]]},"references-count":0,"journal-issue":{"issue":"170","published-online":{"date-parts":[[2026,1,10]]}},"URL":"https:\/\/doi.org\/10.53680\/vertex.v36i170.943","relation":{},"ISSN":["2718-904X","0327-6139"],"issn-type":[{"value":"2718-904X","type":"electronic"},{"value":"0327-6139","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,10]]}}}