{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T19:18:14Z","timestamp":1783711094464,"version":"3.55.0"},"reference-count":0,"publisher":"POLEMOS S.A.","issue":"172","license":[{"start":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:00:00Z","timestamp":1783641600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vertex Rev Arg Psiquiatr"],"abstract":"<jats:p>Este documento constituye la cuarta y \u00faltima parte del Primer Consenso Argentino sobre el Manejo de la Esquizofrenia, desarrollado por la Asociaci\u00f3n Argentina de Psiquiatr\u00eda Biol\u00f3gica (AAPB). En continuidad con los objetivos planteados en las secciones previas, esta etapa del consenso se centra en el abordaje integral de la esquizofrenia en poblaciones especiales y en situaciones cl\u00ednicas de alta complejidad. La presente secci\u00f3nincluye una revisi\u00f3n cr\u00edtica y una valoraci\u00f3n experta de la evidencia cient\u00edfica disponible sobre: a) el manejo de la esquizofrenia resistente y ultrarresistente al tratamiento; b) el abordaje de la esquizofrenia en ni\u00f1os y adolescentes; c) el tratamiento de mujeres con esquizofrenia durante el per\u00edodo perinatal; d) el manejo de la esquizofrenia en adultos mayores; e) la prevenci\u00f3n y el abordaje del suicidio en pacientes con esquizofrenia; f) el impacto del estigma y sus implicancias cl\u00ednicas y sociales; g) la relevancia de la actividad f\u00edsica y los h\u00e1bitos saludables en el pron\u00f3stico funcional y cardiometab\u00f3lico; h) los lineamientos actuales para la rehabilitaci\u00f3n psicosocial; i) el abordaje de personas con esquizofrenia en situaci\u00f3n de calle y vulnerabilidad social extrema; y j) los aspectos m\u00e9dico-legales y forenses vinculados a la enfermedad. Finalmente, el documento incorpora una secci\u00f3n especialmente destinada a las asociaciones de familiares y cuidadores de personas con esquizofrenia, destacando el papel central del entorno familiar en el acompa\u00f1amiento terap\u00e9utico, la adherencia al tratamiento y la recuperaci\u00f3n funcional de los pacientes. --- Con la participaci\u00f3n de la Asociaci\u00f3n de Ayuda de Familiares de Personas conEsquizofrenia (AAFE), Argentina.<\/jats:p>","DOI":"10.53680\/vertex.v37i172.1019","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T19:11:08Z","timestamp":1783710668000},"page":"82-147","source":"Crossref","is-referenced-by-count":0,"title":["Primer Consenso Argentino en Esquizofrenia: cuarta parte. 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