{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:19:33Z","timestamp":1783142373022,"version":"3.54.6"},"reference-count":29,"publisher":"The Fukushima Society of Medical Science","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FJMS","Fukushima J. Med. Sci."],"published-print":{"date-parts":[[2026]]},"DOI":"10.5387\/fms.25-00029","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T22:09:06Z","timestamp":1771366146000},"page":"267-273","source":"Crossref","is-referenced-by-count":0,"title":["Leukocytoclastic vasculitis of the extremities secondary to pancreatic cancer and &lt;i&gt;Escherichia coli&lt;\/i&gt; abscess; An unusual case of distinct etiologies in the same patient"],"prefix":"10.5387","volume":"72","author":[{"given":"Shuhei","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Fukushima Medical University School of Medicine"},{"name":"Department of Rheumatology, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fukushima Medical University School of Medicine"},{"name":"Department of Rheumatology, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kanno","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhito","family":"Iwao","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Odajima","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Sumichika","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fukushima Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fukushima Medical University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Shimbo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ohta-Nishinouchi Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Migita","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fukushima Medical University School of Medicine"},{"name":"Department of Rheumatology, St. Francis Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3342","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Arora A, Wetter DA, Gonzalez-Santiago TM, Davis MD, Lohse CM. Incidence of leukocytoclastic vasculitis, 1996 to 2010: a population-based study in Olmsted County, Minnesota. <i>Mayo Clin Proc<\/i>, <b>89<\/b>: 1515-1524, 2014.","DOI":"10.1016\/j.mayocp.2014.04.015"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Fraticelli P, Benfaremo D, Gabrielli A. Diagnosis and management of leukocytoclastic vasculitis. <i>Intern Emerg Med<\/i>, <b>16<\/b>: 831-841, 2021.","DOI":"10.1007\/s11739-021-02688-x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Ekenstam E, Callen JP. Cutaneous leukocytoclastic vasculitis. Clinical and laboratory features of 82 patients seen in private practice. <i>Arch Dermatol<\/i>, <b>120<\/b>: 484-489, 1984.","DOI":"10.1001\/archderm.1984.01650400066014"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Sams WM, Jr., Thorne EG, Small P, Mass MF, McIntosh RM, Stanford RE. Leukocytoclastic vasculitis. <i>Arch Dermatol<\/i>, <b>112<\/b>: 219-226, 1976.","DOI":"10.1001\/archderm.1976.01630260039011"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Loricera J, Calvo-R\u00edo V, Ortiz-Sanju\u00e1n F, <i>et al.<\/i> The spectrum of paraneoplastic cutaneous vasculitis in a defined population: incidence and clinical features. <i>Medicine (Baltimore)<\/i>, <b>92<\/b>: 331-343, 2013.","DOI":"10.1097\/MD.0000000000000009"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Bertero L, Massa F, Metovic J, <i>et al.<\/i> Eighth Edition of the UICC Classification of Malignant Tumours: an overview of the changes in the pathological TNM classification criteria-What has changed and why? <i>Virchows Arch<\/i>, <b>472<\/b>: 519-531, 2018.","DOI":"10.1007\/s00428-017-2276-y"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Evans DB, Rich TA, Byrd DR, <i>et al.<\/i> Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas. <i>Arch Surg<\/i>, <b>127<\/b>: 1335-1339, 1992.","DOI":"10.1001\/archsurg.1992.01420110083017"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Verbeke C, H\u00e4berle L, Lenggenhager D, Esposito I. Pathology assessment of pancreatic cancer following neoadjuvant treatment: Time to move on. <i>Pancreatology<\/i>, <b>18<\/b>: 467-476, 2018.","DOI":"10.1016\/j.pan.2018.04.010"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Okusaka T, Nakamura M, Yoshida M, <i>et al.<\/i> Clinical Practice Guidelines for Pancreatic Cancer 2019 From the Japan Pancreas Society: A Synopsis. <i>Pancreas<\/i>, <b>49<\/b>: 326-335, 2020.","DOI":"10.1097\/MPA.0000000000001513"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Uesaka K, Boku N, Fukutomi A, <i>et al<\/i> Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01). <i>Lancet<\/i>, <b>388<\/b>: 248-257, 2016.","DOI":"10.1016\/S0140-6736(16)30583-9"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Sunderk\u00f6tter CH, Zelger B, Chen KR, <i>et al.<\/i> Nomenclature of Cutaneous Vasculitis: Dermatologic Addendum to the 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. <i>Arthritis Rheumatol<\/i>, <b>70<\/b>: 171-184, 2018.","DOI":"10.1111\/ddg.13703"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Pulido-P\u00e9rez A, Avil\u00e9s-Izquierdo JA, Su\u00e1rez-Fern\u00e1ndez R. [Cutaneous vasculitis]. <i>Actas Dermosifiliogr<\/i>, <b>103<\/b>: 179-191, 2012.","DOI":"10.1016\/j.adengl.2011.06.001"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Saboe A, Sari MT, Cool CJ, <i>et al.<\/i> Cutaneous Vasculitis and Generalized Lymphadenopathy Associated with Extended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Endocarditis: A Rare Case Report. <i>Infect Dis Ther<\/i>, <b>10<\/b>: 583-593, 2021.","DOI":"10.1007\/s40121-020-00377-4"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Khatri G, Mahajan V, Raina R. Escherichia coli: an uncommon cause of severe urticarial vasculitis. <i>Our Dermatology Online<\/i>, <b>6<\/b>: 365, 2015.","DOI":"10.7241\/ourd.20153.99"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Longley S, Caldwell JR, Panush RS. Paraneoplastic vasculitis. Unique syndrome of cutaneous angiitis and arthritis associated with myeloproliferative disorders. <i>Am J Med<\/i>, <b>80<\/b>: 1027-1030, 1986.","DOI":"10.1016\/0002-9343(86)90660-1"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Voorburg AM, van Beek FT, Slee PH, Seldenrijk CA, Schramel FM. Vasculitis due to gemcitabine. <i>Lung Cancer<\/i>, <b>36<\/b>: 203-205, 2002.","DOI":"10.1016\/S0169-5002(01)00464-0"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Corella F, Dalmau J, Ro\u00e9 E, Garc\u00eda-Navarro X, Alomar A. Cutaneous vasculitis associated with gemcitabine therapy. <i>Clin Exp Dermatol<\/i>, <b>34<\/b>: 97-99, 2009.","DOI":"10.1111\/j.1365-2230.2008.03014.x"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Geisler JP, Schraith DF, Manahan KJ, Sorosky JI. Gemcitabine associated vasculitis leading to necrotizing enterocolitis and death in women undergoing primary treatment for epithelial ovarian\/peritoneal cancer. <i>Gynecol Oncol<\/i>, <b>92<\/b>: 705-707, 2004.","DOI":"10.1016\/j.ygyno.2003.10.050"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Travers P, Goodman A, Poiesz B. Tumor Lysis Syndrome in a Low-Risk Pancreatic Cancer Patient. <i>Case Rep Oncol<\/i>, <b>14<\/b>: 1310-1314, 2021.","DOI":"10.1159\/000512827"},{"key":"20","unstructured":"20. Brinton T, Yousuf T, Steinecker G, Rydel J. A Case of Tumor Lysis Syndrome in a Patient with Pancreatic Adenocarcinoma Treated with Low-Dose Gemcitabine. <i>Ochsner J<\/i>, <b>15<\/b>: 455-456, 2015."},{"key":"21","unstructured":"21. Loricera J, Blanco R, Hern\u00e1ndez JL,<i>et al.<\/i> Cutaneous vasculitis associated with severe bacterial infections. A study of 27 patients from a series of 766 cutaneous vasculitis. <i>Clin Exp Rheumatol<\/i>, <b>33<\/b>: S-36-43, 2015."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Lewis SM, Williams A, Eisenbarth SC. Structure and function of the immune system in the spleen. <i>Sci Immunol<\/i>, <b>4<\/b>, 2019.","DOI":"10.1126\/sciimmunol.aau6085"},{"key":"23","unstructured":"23. Chia D, Barnett EV, Yamagata J, Knutson D, Restivo C, Furst D. Quantitation and characterization of soluble immune complexes precipitated from sera by polyethylene glycol (PEG). <i>Clin Exp Immunol<\/i>, <b>37<\/b>: 399-407, 1979."},{"key":"24","unstructured":"24. Cupps TR, Fauci AS. The vasculitides. <i>Major Probl Intern Med<\/i>, <b>21<\/b>: 1-211, 1981."},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Farcet JP, Weschsler J, Wirquin V, Divine M, Reyes F. Vasculitis in hairy-cell leukemia. <i>Arch Intern Med<\/i>, <b>147<\/b>: 660-664, 1987.","DOI":"10.1001\/archinte.1987.00370040042008"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Rivero SJ, Alger M, Alarc\u00f3n-Segovia D. Splenectomy for hemocytopenia in systemic lupus erythematosus. A controlled appraisal. <i>Arch Intern Med<\/i>, <b>139<\/b>: 773-776, 1979.","DOI":"10.1001\/archinte.1979.03630440039014"},{"key":"27","unstructured":"27. Asherson RA, Gunter K, Daya D, Shoenfeld Y. Multiple autoimmune diseases in a young woman: tuberculosis and splenectomy as possible triggering factors? Another example of the \u201cmosaic\u201d of autoimmunity. <i>J Rheumatol<\/i>, <b>35<\/b>: 1224-1226, 2008."},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Kleiner-Baumgarten A, Schlaeffer F, Keynan A. Multiple autoimmune manifestations in a splenectomized subject with HLA-B8. <i>Arch Intern Med<\/i>, <b>143<\/b>: 1987-1989, 1983.","DOI":"10.1001\/archinte.1983.00350100171032"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Comer M, Bucknall RC. Digital vasculitis after splenectomy in a patient with Felty\u2019s syndrome. <i>Ann Rheum Dis<\/i>, <b>51<\/b>: 908-909, 1992.","DOI":"10.1136\/ard.51.7.908"}],"container-title":["FUKUSHIMA JOURNAL OF MEDICAL SCIENCE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/fms\/72\/3\/72_25-00029\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T05:06:45Z","timestamp":1783141605000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/fms\/72\/3\/72_25-00029\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5387\/fms.25-00029","relation":{},"ISSN":["0016-2590","2185-4610"],"issn-type":[{"value":"0016-2590","type":"print"},{"value":"2185-4610","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"25-00029"}}