{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:05:56Z","timestamp":1791237956068,"version":"4.1.0"},"reference-count":27,"publisher":"Korean Academy of Conservative Dentistry","issue":"4","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2022R1G1A1010061"],"award-info":[{"award-number":["NRF-2022R1G1A1010061"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rde.ac"],"crossmark-restriction":true},"short-container-title":["Restor Dent Endod"],"published-print":{"date-parts":[[2025,11,30]]},"abstract":"<jats:p>Objectives: The aim of this study was to compare the remineralizing capacity of bioactive glass (BGS-7, CGBIO) with other agents.Methods: Twenty caries-free third molars were sectioned and demineralized. Specimens were divided into four groups: (1) control, (2) Clinpro XT varnish (Solventum), (3) 1.23% acidulated phosphate fluoride gel, and (4) a new type of CaO-SiO2-P2O5-B2O3 system of bioactive glass ceramics (BGS-7). Agents were applied and stored in simulated body fluid at 37\u2103 for 2 weeks. Microhardness was measured using the Vickers hardness testing method. Five specimens per group were analyzed using quantitative light-induced fluorescence (QLF) to assess mineral loss. Field-emission scanning electron microscopy (FE-SEM) and energy-dispersive X-ray spectroscopy (EDS) were used to examine the surface morphology and elemental composition. Data were analyzed using paired t-test and one-way analysis of variance (p &lt; 0.05).Results: BGS-7 showed the highest microhardness values and the greatest recovery in QLF analysis (p &lt; 0.05). FE-SEM revealed granular precipitates on demineralized enamel in the BGS-7 group. EDS confirmed the presence of newly formed silicon and fluoride layers.Conclusions: BGS-7 demonstrated superior remineralization capacity compared to other agents, suggesting its potential as an effective remineralizing material.<\/jats:p>","DOI":"10.5395\/rde.2025.50.e33","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T01:45:07Z","timestamp":1760492707000},"page":"e33","update-policy":"https:\/\/doi.org\/10.5395\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The influence of bioactive glass (BGS-7) on enamel remineralization: an in vitro study"],"prefix":"10.5395","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5138-196X","authenticated-orcid":true,"given":"Chaeyoung","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6682-3008","authenticated-orcid":true,"given":"Eunseon","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5445-9923","authenticated-orcid":true,"given":"Kun-Hwa","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3457-1242","authenticated-orcid":true,"given":"Su-Jung","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6869-8562","authenticated-orcid":true,"given":"Yoorina","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3349","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.105489"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.30"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/6539671"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2023-0115"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.identj.2025.04.005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.51847\/tq2fqhs4vz"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0022034519837252"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517709464"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000510180"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/4788668"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/ma12244183"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/ma14133745"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000354655"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1590\/0103-6440201601524"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2025.105579"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-024-05865-2"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2025.105853"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3109\/01480540903373647"},{"key":"ref19","first-page":"540","volume-title":"Quantitative comparison of novel CaO-SiO2-P2O5-B2O3 glass-ceramics (BGS-7) with hydroxyapatite as bone graft extender in rabbit ilium","author":"Lee","year":"2010"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13378"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12040"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2023.01.003"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3390\/jfb14070364"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.4c01680"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4103\/jos.jos_141_21"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.13292"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2021.103633"}],"container-title":["Restorative Dentistry &amp; 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