{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T07:16:27Z","timestamp":1788160587796,"version":"build-2803163510"},"reference-count":38,"publisher":"Korean Academy of Conservative Dentistry","issue":"3","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004595","name":"Universiti Sains Malaysia","doi-asserted-by":"publisher","award":["304\/PPSG\/6315781"],"award-info":[{"award-number":["304\/PPSG\/6315781"]}],"id":[{"id":"10.13039\/501100004595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["rde.ac"],"crossmark-restriction":true},"short-container-title":["Restor Dent Endod"],"published-print":{"date-parts":[[2026,8,31]]},"abstract":"<jats:p>Objectives: This study aimed to determine the relationship between the interfacial properties of proximal cavities (microbial leakage and marginal adaptation) and restorative materials (alkasite, resin composite, and glass hybrid)Methods: This study involved 66 human third molars that were left intact. Standardized Class II cavities were done on the mesial surface. The samples were then divided into five groups: (i) Cention N (CN, Ivoclar Vivadent), (ii) Filtek Z350XT (FZ, 3M ESPE), (iii) EQUIA Forte (GC Corporation), and (iv) two controls. For 40 days, a dual-chamber model containing Streptococcus mutans was used to study microbial leakage. Qualitative assessments of the sectioned samples were also carried out using a scanning electron microscope (SEM). Moreover, this study employed descriptive and Kaplan-Meier analyses, alongside a one-way analysis of variance for additional descriptive comparisons (p &lt; 0.05).Results: Across different restorative materials, notable variations in microbial leakage were recorded. From the supplementary analysis between CN and FZ, a statistically significant difference was demonstrated (p = 0.037). In comparison to other restorative systems, CN also produced a prolonged mean time before microbial leakage occurred. For the interfacial properties of the restorative systems, illustrative information was offered via the SEM images.Conclusions: Regarding microbial leakage, all restorative systems presented their occurrence (despite the constraints of this study). When assessing CN and FZ restorative systems, a slower rate of microbial leakage was also concluded for CN. For the tooth-restoration interface, qualitative data were verified through SEM observations.<\/jats:p>","DOI":"10.5395\/rde.2026.51.e31","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:42:16Z","timestamp":1785224536000},"page":"e31","update-policy":"https:\/\/doi.org\/10.5395\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Microbial leakage and marginal adaptation of alkasite restorative material in Class II cavities: an in vitro study"],"prefix":"10.5395","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8968-9548","authenticated-orcid":true,"given":"Kah 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