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To diagnose VTE, noninvasive cost-effective diagnostic algorithms including clinical probability assessment and D-dimer measurement may be employed followup by compression ultrasonography for suspected DVT patients and multidetector computed tomography angiography for suspected PE patients. There are pharmacological and mechanical interventions to manage and prevent VTE. The pharmacological approaches mainly target pathways in coagulation cascade nonspecifically: conventional anticoagulants or specifically: new generation of anticoagulants. Excess bleeding is one of the major risk factors for pharmacological interventions. Hence, nonpharmacological or mechanical approaches such as inferior vena cava filters, graduated compression stockings, and intermittent pneumatic compression devices in combination with pharmacological interventions or alone may be a good approach to manage VTE.<\/jats:p>","DOI":"10.5402\/2011\/124610","type":"journal-article","created":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T21:30:25Z","timestamp":1318887025000},"page":"1-7","source":"Crossref","is-referenced-by-count":81,"title":["Venous Thromboembolism: Classification, Risk Factors, Diagnosis, and Management"],"prefix":"10.5402","volume":"2011","author":[{"given":"Fatemeh","family":"Moheimani","sequence":"first","affiliation":[{"name":"Thrombosis and Vascular Diseases Laboratory, Health Innovations Research Institute and School of Medical Sciences, RMIT University, P.O. 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