{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T01:48:07Z","timestamp":1751420887398},"reference-count":20,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2011,7,16]],"date-time":"2011-07-16T00:00:00Z","timestamp":1310774400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Gastroenterology"],"published-print":{"date-parts":[[2011,7,16]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Study the functional results and mucosal changes in the ileal pouch after restorative proctocolectomy with J-reservoir for ulcerative colitis. <jats:italic>Material and Methods<\/jats:italic>. Followup study of 125 patients with J-reservoir with one disease-specific- and one general (SF-36) quality of life-questionnaire, rectoscopy with biopsies, and stool samples to evaluate inflammation, dysplasia, presence of <jats:italic>Helicobacter pylori<\/jats:italic>  and calprotectin level. <jats:italic>Results<\/jats:italic>.  Fourteen J-reservoirs were removed or deactivated, leaving 111 patients for followup. The followup time was 6.8 (1\u201315) years. 87.4% of the patients were satisfied. 93.1% had some kind of functional restriction: food- (75.5%), social- (28.9%), physical- (37%) or sexual restriction (15.3%). 18.6% had often or sometimes faecal incontinence. Low daytime faecal frequency was associated with good quality of life. 13 patients (12.6%) had a less favourable result. There was no pouch-dysplasia. Calprotectin levels were increased in patients with visible pouch inflammation or history of pouchitis. HP was diagnosed by RUT in 42.3%, but was not associated with inflammation or pouchitis. <jats:italic>Conclusions<\/jats:italic>. Most patients were satisfied with the J-reservoir in spite of a high frequency of various restrictions. 12.6% (13 patients) had a less favourable functional result, partly due to a high frequency of defecations, pain, pouchitis and inflammation.<\/jats:p>","DOI":"10.5402\/2011\/430171","type":"journal-article","created":{"date-parts":[[2011,8,28]],"date-time":"2011-08-28T08:43:20Z","timestamp":1314521000000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Long-Term Followup of Patients with Active J-Reservoirs after Restorative Proctocolectomy for Ulcerative Colitis with regard to Reservoir Function, Mucosal Changes, and Quality of Life"],"prefix":"10.5402","volume":"2011","author":[{"given":"Ola","family":"R\u00f8kke","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Surgery, Akershus University Hospital, 1478 L\u00f8renskog, Norway"},{"name":"Faculty of Medicine, University of Oslo, 0316 Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Knut","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Diakonissehjemmet Hospital, Haraldsplass, 5021 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torill","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Haukeland University Hospital, 5021 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8lvi-May","family":"Ristesund","sequence":"additional","affiliation":[{"name":"Department of Surgery, Haukeland University Hospital, 5021 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geir Egil","family":"Eide","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research, Haukeland University Hospital, 5021 Bergen, Norway"},{"name":"Research Group on Lifestyle Epidemiology, Department of Public Health and Primary Health Care, University of Bergen, 5020 Bergen, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gitta Erika","family":"Turowski","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ullevaal University Hospital, 0424 Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"6130","key":"1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1136\/bmj.2.6130.85","volume":"2","year":"1978","journal-title":"British Medical Journal"},{"issue":"1","key":"2","first-page":"23","volume":"7","year":"2005","journal-title":"Israel Medical Association Journal"},{"issue":"1","key":"3","first-page":"30","volume":"45","year":"2002","journal-title":"Diseases of the Colon and 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